USO1 and RAB1A

Number of citations of the paper that reports this interaction (PMID 10903204)
122

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		USO1	RAB1A
Gene Name		USO1 vesicle transport factor	RAB1A, member RAS oncogene family
Image
Gene Ontology Annotations	Cellular Component	Golgi Membrane Nucleolus Endoplasmic Reticulum Golgi Apparatus Golgi Stack Cytosol ER To Golgi Transport Vesicle Membrane Membrane Perinuclear Region Of Cytoplasm	Golgi Membrane Early Endosome Endoplasmic Reticulum Membrane Cytosol Melanosome Extracellular Vesicular Exosome
	Molecular Function	Protein Transporter Activity Poly(A) RNA Binding	GTPase Activity Protein Binding GTP Binding GDP Binding
	Biological Process	Mitotic Cell Cycle Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Transcytosis Golgi Vesicle Docking Vesicle Fusion With Golgi Apparatus Membrane Fusion	Autophagic Vacuole Assembly Mitotic Cell Cycle Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Endocytosis Autophagy Golgi Organization Vesicle-mediated Transport Cell Migration Virion Assembly Growth Hormone Secretion Melanosome Transport Rab Protein Signal Transduction Substrate Adhesion-dependent Cell Spreading Cilium Assembly Defense Response To Bacterium Vesicle Transport Along Microtubule Interleukin-8 Secretion Cargo Loading Into COPII-coated Vesicle Establishment Of Endothelial Intestinal Barrier Positive Regulation Of Glycoprotein Metabolic Process
Pathways		Mitotic Prophase Golgi Cisternae Pericentriolar Stack Reorganization Cell Cycle, Mitotic M Phase	Mitotic Prophase Golgi Cisternae Pericentriolar Stack Reorganization Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		24 interactors: AKAP9 BET1L C1orf94 CASP3 CASP8 CSNK2B DUSP12 EEA1 GABPB1 GAK GBF1 GOLGA2 GOLGB1 GOSR1 GOSR2 NSF PHYKPL PLCG1 RAB1A SCFD1 STX5 STXBP1 XPO7 YKT6	28 interactors: ADCK1 CAPNS1 CDKN1A CHM CHML CREB1 FSCN1 GOLGA2 GOLGA5 GORASP2 HIVEP1 MAPRE3 MICAL1 MICALL1 OCRL PSMD7 RABAC1 RABEP1 RABGGTA RABGGTB RABIF RFK RUSC2 SLC16A8 SYT5 TBC1D17 USO1 ZNF593
Entrez ID		8615	5861
HPRD ID		09135	01538
Ensembl ID		ENSG00000138768	ENSG00000138069
Uniprot IDs		O60763	B7Z8M7 P62820 Q5U0I6
PDB IDs		2W3C	2FOL 2WWX 3L0I 3SFV 3TKL 4FMB 4FMC 4FMD 4FME 4IRU 4JVS
Enriched GO Terms of Interacting Partners?		Membrane Fusion Golgi Vesicle Transport Vesicle-mediated Transport Vesicle Organization Membrane Organization Retrograde Transport, Endosome To Golgi Vesicle Docking Membrane Docking ER To Golgi Vesicle-mediated Transport Endosomal Transport Intracellular Transport Establishment Of Localization In Cell Cytoplasmic Transport Vesicle Fusion Protein Transport Establishment Of Protein Localization Cellular Localization Organelle Fusion Golgi Organization Establishment Of Vesicle Localization Post-Golgi Vesicle-mediated Transport Vesicle Localization Endomembrane System Organization Protein Localization Transport Organelle Organization Positive Regulation Of Protein Metabolic Process Establishment Of Organelle Localization Vesicle Docking Involved In Exocytosis Positive Regulation Of Metabolic Process Intra-Golgi Vesicle-mediated Transport Endocytosis Vesicle Fusion With Golgi Apparatus Organelle Localization Positive Regulation Of Cellular Metabolic Process Secretion By Cell Exocytosis Secretion Regulation Of Cellular Localization Cell Morphogenesis Regulation Of Vesicle-mediated Transport Positive Regulation Of Cellular Protein Metabolic Process Cell Morphogenesis Involved In Differentiation Retrograde Vesicle-mediated Transport, Golgi To ER Synaptic Vesicle Endocytosis Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Synaptic Vesicle Recycling Regulation Of Protein Metabolic Process Regulation Of Intracellular Transport Regulation Of Kinase Activity	Protein Geranylgeranylation Protein Prenylation Positive Regulation Of Catalytic Activity Regulation Of Catalytic Activity Positive Regulation Of Hydrolase Activity Positive Regulation Of GTPase Activity Mitotic Cell Cycle Regulation Of GTPase Activity Membrane Fusion Positive Regulation Of Metabolic Process Protein Transport Establishment Of Protein Localization Visual Perception Sensory Perception Of Light Stimulus Slow Endocytic Recycling Riboflavin Biosynthetic Process FMN Biosynthetic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Membrane Organization Positive Regulation Of Microtubule Plus-end Binding Golgi Vesicle Docking Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Cell Cycle Positive Regulation Of Cell Cycle Arrest Cellular Process Positive Regulation Of NAD(P)H Oxidase Activity DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Cell Cycle Apoptotic Process Protein Localization Vesicle-mediated Transport Programmed Cell Death Signal Transduction In Response To DNA Damage Establishment Of Localization In Cell Mitotic DNA Damage Checkpoint Cell Death Death Intestinal Epithelial Cell Maturation Riboflavin Metabolic Process Regulation Of Cell Cycle Arrest Intracellular Transport Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Mitotic DNA Integrity Checkpoint
Tagcloud ?		absorbed altogether autophagosomes biogenesis coat compartment copi copii cups endosomal enter exit export golgi grh1 pik1 relocates relocation return sec7 secrete sed5 snare sort starvation tethering unconventional vacuole vps34	added become broadly characterises eevs enveloped exploits facilitating golgi growing gtpase highlighting ievs immunofluorescence imvs list maintenance mature numerous optimal proviral refined replication require stranded vaccinia vacv virions wrapping
Tagcloud (Difference) ?		absorbed altogether autophagosomes biogenesis coat compartment copi copii cups endosomal enter exit export grh1 pik1 relocates relocation return sec7 secrete sed5 snare sort starvation tethering unconventional vacuole vps34	added become broadly characterises eevs enveloped exploits facilitating growing gtpase highlighting ievs immunofluorescence imvs list maintenance mature numerous optimal proviral refined replication require stranded vaccinia vacv virions wrapping
Tagcloud (Intersection) ?		golgi