USO1 and GBF1

Number of citations of the paper that reports this interaction (PMID 12634853)
26

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		USO1	GBF1
Gene Name		USO1 vesicle transport factor	golgi brefeldin A resistant guanine nucleotide exchange factor 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Nucleolus Endoplasmic Reticulum Golgi Apparatus Golgi Stack Cytosol ER To Golgi Transport Vesicle Membrane Membrane Perinuclear Region Of Cytoplasm	Golgi Membrane Mitochondrion Peroxisome Endoplasmic Reticulum Lumen Golgi Apparatus Golgi Stack Cis-Golgi Network Trans-Golgi Network Membrane
	Molecular Function	Protein Transporter Activity Poly(A) RNA Binding	ARF Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Mitotic Cell Cycle Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Transcytosis Golgi Vesicle Docking Vesicle Fusion With Golgi Apparatus Membrane Fusion	Retrograde Vesicle-mediated Transport, Golgi To ER Post-Golgi Vesicle-mediated Transport Organelle Organization Viral Process Vesicle-mediated Transport Regulation Of ARF Protein Signal Transduction Positive Regulation Of GTPase Activity COPI Coating Of Golgi Vesicle Membrane Organization
Pathways		Mitotic Prophase Golgi Cisternae Pericentriolar Stack Reorganization Cell Cycle, Mitotic M Phase	Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance VxPx cargo-targeting to cilium COPI Mediated Transport Assembly of the primary cilium trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding Golgi to ER Retrograde Transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		24 interactors: AKAP9 BET1L C1orf94 CASP3 CASP8 CSNK2B DUSP12 EEA1 GABPB1 GAK GBF1 GOLGA2 GOLGB1 GOSR1 GOSR2 NSF PHYKPL PLCG1 RAB1A SCFD1 STX5 STXBP1 XPO7 YKT6	3 interactors: PNPLA2 USO1 YWHAG
Entrez ID		8615	8729
HPRD ID		09135	04740
Ensembl ID		ENSG00000138768	ENSG00000107862
Uniprot IDs		O60763	Q149P0 Q149P1 Q92538
PDB IDs		2W3C
Enriched GO Terms of Interacting Partners?		Membrane Fusion Golgi Vesicle Transport Vesicle-mediated Transport Vesicle Organization Membrane Organization Retrograde Transport, Endosome To Golgi Vesicle Docking Membrane Docking ER To Golgi Vesicle-mediated Transport Endosomal Transport Intracellular Transport Establishment Of Localization In Cell Cytoplasmic Transport Vesicle Fusion Protein Transport Establishment Of Protein Localization Cellular Localization Organelle Fusion Golgi Organization Establishment Of Vesicle Localization Post-Golgi Vesicle-mediated Transport Vesicle Localization Endomembrane System Organization Protein Localization Transport Organelle Organization Positive Regulation Of Protein Metabolic Process Establishment Of Organelle Localization Vesicle Docking Involved In Exocytosis Positive Regulation Of Metabolic Process Intra-Golgi Vesicle-mediated Transport Endocytosis Vesicle Fusion With Golgi Apparatus Organelle Localization Positive Regulation Of Cellular Metabolic Process Secretion By Cell Exocytosis Secretion Regulation Of Cellular Localization Cell Morphogenesis Regulation Of Vesicle-mediated Transport Positive Regulation Of Cellular Protein Metabolic Process Cell Morphogenesis Involved In Differentiation Retrograde Vesicle-mediated Transport, Golgi To ER Synaptic Vesicle Endocytosis Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Synaptic Vesicle Recycling Regulation Of Protein Metabolic Process Regulation Of Intracellular Transport Regulation Of Kinase Activity	Golgi Vesicle Docking Acylglycerol Acyl-chain Remodeling Negative Regulation Of Sequestering Of Triglyceride Vesicle Fusion With Golgi Apparatus Positive Regulation Of Triglyceride Catabolic Process Transcytosis Lipid Particle Organization Negative Regulation Of Lipid Storage Organelle Organization Triglyceride Catabolic Process Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Mitotic Cell Cycle Acylglycerol Catabolic Process Positive Regulation Of Lipid Catabolic Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Membrane Organization Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Triglyceride Metabolic Process Intracellular Protein Transport Lipid Storage Vesicle Fusion Regulation Of Lipid Catabolic Process Regulation Of Lipid Storage Positive Regulation Of Mitochondrion Organization Cell Cycle Cellular Protein Localization Organelle Fusion Protein Transport Vesicle Docking Establishment Of Protein Localization Membrane Docking Regulation Of Mitochondrion Organization Intracellular Transport Triglyceride Metabolic Process ER To Golgi Vesicle-mediated Transport
Tagcloud ?		absorbed altogether autophagosomes biogenesis coat compartment copi copii cups endosomal enter exit export golgi grh1 pik1 relocates relocation return sec7 secrete sed5 snare sort starvation tethering unconventional vacuole vps34	accumulated arf arf1 arfgef caenorhabditis cdc48 cerevisiae coat contact contacts elegans evolutionarily fractionated fzo1 gem1 gtpase initiating interacted mitochondria mitochondrial mitofusin modifying resolved saccharomyces traffic unexpected vesicular worms
Tagcloud (Difference) ?		absorbed altogether autophagosomes biogenesis compartment copi copii cups endosomal enter exit export golgi grh1 pik1 relocates relocation return sec7 secrete sed5 snare sort starvation tethering unconventional vacuole vps34	accumulated arf arf1 arfgef caenorhabditis cdc48 cerevisiae contact contacts elegans evolutionarily fractionated fzo1 gem1 gtpase initiating interacted mitochondria mitochondrial mitofusin modifying resolved saccharomyces traffic unexpected vesicular worms
Tagcloud (Intersection) ?		coat