EEA1 and ZFYVE16

Number of citations of the paper that reports this interaction (PMID 14613930)
6

Data Source:
HPRD (in vitro)

		EEA1	ZFYVE16
Gene Name		early endosome antigen 1	zinc finger, FYVE domain containing 16
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Early Endosome Cytosol Serine-pyruvate Aminotransferase Complex Membrane Extrinsic Component Of Plasma Membrane Cytoplasmic Vesicle Early Endosome Membrane Axonal Spine Recycling Endosome Extracellular Vesicular Exosome	Cytoplasm Early Endosome Early Endosome Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Calmodulin Binding 1-phosphatidylinositol Binding Zinc Ion Binding GTP-dependent Protein Binding Protein Homodimerization Activity	Protein Binding 1-phosphatidylinositol Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Protein Transporter Activity Metal Ion Binding
	Biological Process	Endocytosis Vesicle Fusion Synaptic Vesicle To Endosome Fusion Early Endosome To Late Endosome Transport	Protein Targeting To Lysosome Signal Transduction Vesicle Organization Endosomal Transport Regulation Of Endocytosis BMP Signaling Pathway
Pathways		Toll-Like Receptors Cascades Toll Like Receptor 9 (TLR9) Cascade Innate Immune System	Signaling by BMP
Drugs		Inositol 1,3-Bisphosphate
Diseases
GWAS
Protein-Protein Interactions		11 interactors: IGF1R MAPK14 RAB22A RAB5A RAB5B RAB5C STX12 STX6 TOM1 USO1 ZFYVE16	5 interactors: APP EEA1 PPP1CA RNF11 TOM1
Entrez ID		8411	9765
HPRD ID		05460	10319
Ensembl ID		ENSG00000102189	ENSG00000039319
Uniprot IDs		Q15075	Q7Z3T8
PDB IDs		1HYI 1HYJ 1JOC 3MJH	3T7L
Enriched GO Terms of Interacting Partners?		Intracellular Protein Transport Endosomal Transport Cellular Protein Localization Protein Transport Establishment Of Protein Localization Intracellular Transport Protein Localization Establishment Of Localization In Cell Rab Protein Signal Transduction Vesicle-mediated Transport Ras Protein Signal Transduction Cellular Localization Endosome Organization Regulation Of Endocytosis Vesicle Fusion Vesicle Organization Plasma Membrane To Endosome Transport Small GTPase Mediated Signal Transduction Organelle Fusion Cytoplasmic Transport Regulation Of Vesicle-mediated Transport Membrane Fusion Transport Intracellular Signal Transduction Regulation Of Cellular Component Organization Organelle Organization P38MAPK Cascade Inactivation Of MAPKK Activity Vesicle Docking Membrane Docking Endomembrane System Organization Regulation Of Vesicle Size Golgi Vesicle Docking Receptor Internalization Involved In Canonical Wnt Signaling Pathway Regulation Of Endosome Size Positive Regulation Of Brown Fat Cell Differentiation Myoblast Differentiation Involved In Skeletal Muscle Regeneration Regulation Of Brown Fat Cell Differentiation Endocytosis Golgi Ribbon Formation Signal Transduction Positive Regulation Of Steroid Hormone Biosynthetic Process Exocrine Pancreas Development Vesicle Fusion With Golgi Apparatus Positive Regulation Of Hormone Biosynthetic Process 3'-UTR-mediated MRNA Stabilization Stress-induced Premature Senescence Signaling Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Protein Targeting To Lysosome	Endocytosis Synaptic Vesicle To Endosome Fusion Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Endosomal Transport Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling Regulation Of Glycogen Catabolic Process Response To Light Stimulus Vesicle-mediated Transport
Tagcloud ?		appl1 characterised colocalisation colocalises compartments employ endocytic endosome endosomes engages entered escrt gradually intermediates intralumenal labelled localise localises move snx15 solely sorts subpixel suite transit transporting ubiquitinated vacuolar whilst
Tagcloud (Difference) ?		appl1 characterised colocalisation colocalises compartments employ endocytic endosome endosomes engages entered escrt gradually intermediates intralumenal labelled localise localises move snx15 solely sorts subpixel suite transit transporting ubiquitinated vacuolar whilst
Tagcloud (Intersection) ?