PARP2 and CENPB

Number of citations of the paper that reports this interaction (PMID 12217960)
17

Data Source:
HPRD (in vivo)

		PARP2	CENPB
Gene Name		poly (ADP-ribose) polymerase 2	centromere protein B, 80kDa
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus	Chromosome, Centromeric Region Nucleus Chromosome
	Molecular Function	DNA Binding NAD+ ADP-ribosyltransferase Activity Protein Binding	Chromatin Binding Satellite DNA Binding Centromeric DNA Binding Sequence-specific DNA Binding
	Biological Process	DNA Repair Base-excision Repair Protein ADP-ribosylation Extrinsic Apoptotic Signaling Pathway	Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: BUB3 CASP8 CENPA CENPB PARP1 XRCC1	17 interactors: ANXA7 APP CDKN1A CSNK2B FBXO25 GADD45A GFI1B GSK3B HAND2 NR3C1 PARP1 PARP2 PIN1 RPS6KA6 SMN1 TAC1 TK1
Entrez ID		10038	1059
HPRD ID		09660	00314
Ensembl ID		ENSG00000129484	ENSG00000125817
Uniprot IDs		Q9UGN5	P07199
PDB IDs		3KCZ 3KJD	1BW6 1HLV 1UFI
Enriched GO Terms of Interacting Partners?		Macrophage Differentiation Base-excision Repair Myeloid Leukocyte Differentiation Syncytiotrophoblast Cell Differentiation Involved In Labyrinthine Layer Development Regulation Of Growth Rate Protein Poly-ADP-ribosylation TRAIL-activated Apoptotic Signaling Pathway	Regulation Of Binding Negative Regulation Of Phosphorylation Regulation Of Signaling Anatomical Structure Development Cellular Metabolic Process Response To External Stimulus Positive Regulation Of Transcription Regulatory Region DNA Binding Regulation Of Phosphorylation Response To Organic Substance System Development Positive Regulation Of Cellular Metabolic Process Response To Stress Regulation Of DNA Binding Response To Hormone Apoptotic Process Regulation Of Signal Transduction Regulation Of Phosphorus Metabolic Process Signal Transduction In Response To DNA Damage Negative Regulation Of Cellular Metabolic Process Developmental Process Behavior Programmed Cell Death Cell Death Death Regulation Of Protein Phosphorylation Response To Abiotic Stimulus Multicellular Organismal Development Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Binding Tube Development Positive Regulation Of Protein Phosphorylation Suckling Behavior Regulation Of Protein Kinase Activity Cellular Protein Modification Process Regulation Of Transcription Regulatory Region DNA Binding Positive Regulation Of Protein Metabolic Process Axon Guidance Protein ADP-ribosylation Regulation Of Kinase Activity Response To Glucocorticoid Signal Transduction Negative Regulation Of MAPK Cascade Positive Regulation Of Metabolic Process Response To Corticosteroid Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Import Into Nucleus Cellular Response To DNA Damage Stimulus Positive Regulation Of Phosphorylation Response To Organic Cyclic Compound Response To Inorganic Substance
Tagcloud ?		abt actively adp azd bsi continues crystal detailed explored guide heightened indications inhibitors insight manifesting modes parp1 parp5a parp5b poly rational relevance ribose stranded tankyrase tnks1 tnks2 valuable	agreement altman asian bland cenpa cohen fibrillarin iif immunoassay interstitial kappa ku lia limits nc ncs nor90 oa outside plots pmscl100 ro52 ro60 rp155 sle ssc stored telangiectasia utility
Tagcloud (Difference) ?		abt actively adp azd bsi continues crystal detailed explored guide heightened indications inhibitors insight manifesting modes parp1 parp5a parp5b poly rational relevance ribose stranded tankyrase tnks1 tnks2 valuable	agreement altman asian bland cenpa cohen fibrillarin iif immunoassay interstitial kappa ku lia limits nc ncs nor90 oa outside plots pmscl100 ro52 ro60 rp155 sle ssc stored telangiectasia utility
Tagcloud (Intersection) ?