CASP2 and CASP8

  • Number of citations of the paper that reports this interaction (PMID 8962078)
  • 66
  • Data Source:
  • BioGRID (enzymatic study)

CASP2

CASP8

Gene Name caspase 2, apoptosis-related cysteine peptidase caspase 8, apoptosis-related cysteine peptidase
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 30 interactors: ADCYAP1 BID BIRC2 CASP10 CASP14 CASP3 CASP7 CASP8 CCND3 CFLAR CRADD CSNK2A1 DCTN1 DSP EEF1A1 GOLGA3 GRB2 KPNA2 MDM2 MZB1 NLRP1 NOD1 NOL3 PIDD1 RAI1 RB1 RPL30 RXRA SUMO1 UBE2I 91 interactors: APAF1 APP AR ATG4D BCAP31 BCL2 BCL2L1 BFAR BID BIRC6 CASP1 CASP10 CASP14 CASP2 CASP3 CASP4 CASP6 CASP7 CASP8AP2 CASP9 CDH1 CDK11B CDKN1B CFLAR CHD3 CHUK COPS6 CRADD CTNNB1 DEDD DEDD2 EDA2R EIF2AK2 FADD FAF1 FAS FYN GMEB1 GRIA1 GZMB HDAC7 HECTD3 HIP1 IKBKB IKBKG ILK KRT18 MAP1LC3B MAP3K14 MAP4K4 MAPK1 MAPK3 MAPT NOD1 NOL3 NR1H4 PARK2 PARK7 PARP1 PARP2 PCYT1A PDIA6 PEA15 PIAS1 PICALM PLA2G4B PLEC PLIN4 PRDX6 PRKCI PRKCZ PSEN1 PSEN2 RALBP1 RB1 RIPK1 RIPK2 RYBP SNRPD3 SRF STK24 SUMO1 TFCP2 TNFRSF10A TNFRSF10B TOPORS TRAF1 TRAF2 TRAF6 USO1 VIM
Entrez ID 835 841
HPRD ID 02800 03459
Ensembl ID ENSG00000106144 ENSG00000064012
Uniprot IDs C9JRR9 D3DXD8 D3DXD9 P42575 Q14790
PDB IDs 1PYO 2P2C 3R5J 3R6G 3R6L 3R7B 3R7N 3R7S 3RJM 1F9E 1I4E 1QDU 1QTN 2C2Z 2FUN 2K7Z 2Y1L 3H11 3KJN 3KJQ 4JJ7
Enriched GO Terms of Interacting Partners?
Tagcloud ?
amplified  array  athymic  caspase  counterparts  delayed  e1a  emu  enhances  extended  lymphoma  maintenance  mammary  mmtv  mycn  neu  neuroblastoma  nude  observations  oncogene  paraspinal  predominantly  ras  subset  surprisingly  th  thoracic  tumorigenesis  vascularized 
10mum  abeta42  abeta43  aif  carnosic  cascades  casp3  casp4  casp9  casps  concurrently  diterpene  herbs  ingestion  initiator  labiate  monomer  neurotoxicity  neurotrophic  oligomerization  oligomers  parp  phenolic  ribose  rosemary  sage  serves  sy5y 
Tagcloud (Difference) ?
amplified  array  athymic  caspase  counterparts  delayed  e1a  emu  enhances  extended  lymphoma  maintenance  mammary  mmtv  mycn  neu  neuroblastoma  nude  observations  oncogene  paraspinal  predominantly  ras  subset  surprisingly  th  thoracic  tumorigenesis  vascularized 
10mum  abeta42  abeta43  aif  carnosic  cascades  casp3  casp4  casp9  casps  concurrently  diterpene  herbs  ingestion  initiator  labiate  monomer  neurotoxicity  neurotrophic  oligomerization  oligomers  parp  phenolic  ribose  rosemary  sage  serves  sy5y 
Tagcloud (Intersection) ?