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HIST1H2AL and GADD45A
Number of citations of the paper that reports this interaction (PMID
10022855
)
48
Data Source:
HPRD
(in vivo)
HIST1H2AL
GADD45A
Gene Name
histone cluster 1, H2al
growth arrest and DNA-damage-inducible, alpha
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleosome
Nucleus
Extracellular Vesicular Exosome
Nucleus
Cytoplasm
Molecular Function
DNA Binding
Protein Binding
Enzyme Binding
Protein Heterodimerization Activity
Core Promoter Binding
Protein Binding
Biological Process
Biological_process
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Activation Of MAPKKK Activity
DNA Repair
Negative Regulation Of Protein Kinase Activity
Apoptotic Process
Cell Cycle Arrest
Centrosome Cycle
Signal Transduction In Response To DNA Damage
Positive Regulation Of Apoptotic Process
Positive Regulation Of JNK Cascade
Cellular Response To Mechanical Stimulus
Cellular Response To Ionizing Radiation
Positive Regulation Of P38MAPK Cascade
Positive Regulation Of Reactive Oxygen Species Metabolic Process
Pathways
Chromatin modifying enzymes
HDACs deacetylate histones
Chromatin organization
HATs acetylate histones
RMTs methylate histone arginines
Drugs
Diseases
GWAS
Protein-Protein Interactions
5 interactors:
BRD7
CRP
GADD45A
SAP30
TERF2IP
65 interactors:
ADAP1
ASCC2
AURKA
BAG6
C14orf1
CCNB1
CDK1
CDK11A
CDKN1A
CENPB
CHD3
CLEC3B
DCTN2
DNAJC13
EEF1A1
EEF1G
FAM83D
FAS
FBN3
FTL
GADD45GIP1
GAPDH
GBP2
GNB2
HIST1H1A
HIST1H2AL
HIST2H2BE
HIST3H3
HIST4H4
IGHM
IGSF21
JMJD1C
KHSRP
LMO4
MAP3K4
MAPK14
MASP1
MDM2
MICAL1
MIDN
MPP1
NPM1
NRBP1
NUCB2
PCNA
PFKFB4
PPARA
PSMC3
PTN
PTPRK
QARS
RAI1
RBPJ
RPS2
RXRA
SH3GLB1
SPTBN4
SYNE4
TLE1
TP53
UBE2D1
UBR1
VIM
ZHX1
ZNF135
Entrez ID
8332
1647
HPRD ID
09103
00528
Ensembl ID
ENSG00000198374
ENSG00000116717
Uniprot IDs
A4FTV9
P0C0S8
A5JUZ3
P24522
PDB IDs
2KG4
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Reactive Oxygen Species Metabolic Process
Negative Regulation Of DNA Recombination At Telomere
Negative Regulation Of Cellular Metabolic Process
Regulation Of Reactive Oxygen Species Metabolic Process
Regulation Of Chromosome Organization
Protection From Non-homologous End Joining At Telomere
Telomere Capping
Protein Localization To Chromosome, Telomeric Region
Negative Regulation Of Vasodilation
Activation Of MAPKKK Activity
Positive Regulation Of P38MAPK Cascade
Positive Regulation Of Superoxide Anion Generation
Telomere Maintenance Via Telomerase
Negative Regulation Of Telomere Maintenance
Opsonization
Regulation Of Double-strand Break Repair Via Homologous Recombination
Regulation Of Superoxide Anion Generation
Regulation Of Interleukin-8 Secretion
Regulation Of P38MAPK Cascade
Regulation Of Metabolic Process
Negative Regulation Of Macrophage Derived Foam Cell Differentiation
Negative Regulation Of Cell Cycle
Negative Regulation Of Lipid Storage
Regulation Of Telomere Maintenance
RNA-dependent DNA Replication
Positive Regulation Of Histone Acetylation
Regulation Of Cellular Component Organization
Negative Regulation Of DNA Recombination
Positive Regulation Of Peptidyl-lysine Acetylation
Positive Regulation Of Protein Acetylation
Regulation Of Double-strand Break Repair
Nucleobase-containing Compound Metabolic Process
Protein Localization To Chromosome
Response To Lead Ion
Telomere Maintenance Via Telomere Lengthening
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Gene Expression
Transcription, DNA-templated
Acute-phase Response
Cellular Nitrogen Compound Metabolic Process
RNA Biosynthetic Process
Regulation Of Macrophage Derived Foam Cell Differentiation
Regulation Of Vasodilation
Regulation Of Histone Acetylation
Cellular Response To Calcium Ion
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Metabolic Process
Cell Cycle
Cell Cycle Process
Regulation Of Gene Expression
Mitotic Cell Cycle
Mitotic Cell Cycle Process
Cellular Response To Organic Substance
Regulation Of Protein Metabolic Process
Organelle Organization
DNA Packaging
DNA Conformation Change
Negative Regulation Of Cellular Metabolic Process
Apoptotic Process
Programmed Cell Death
Regulation Of Cellular Protein Metabolic Process
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Chromosome Organization
Cell Aging
Protein Complex Assembly
Chromatin Organization
Negative Regulation Of Cell Cycle
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Cell Death
Death
Positive Regulation Of Protein Metabolic Process
Cell Cycle Checkpoint
Positive Regulation Of Cellular Protein Catabolic Process
Response To Organic Substance
DNA Damage Checkpoint
Chromatin Assembly Or Disassembly
Stress-induced Premature Senescence
Immune Response
Mitotic Cell Cycle Checkpoint
Positive Regulation Of Cellular Protein Metabolic Process
Signal Transduction In Response To DNA Damage
Negative Regulation Of Gene Expression
Mitotic DNA Damage Checkpoint
Immune System Process
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Negative Regulation Of Cell Death
Positive Regulation Of Metabolic Process
Innate Immune Response
Mitotic DNA Integrity Checkpoint
Response To Toxic Substance
Positive Regulation Of Cell Cycle
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Mitotic Cell Cycle
Positive Regulation Of Proteolysis
Cellular Response To Oxygen Levels
Tagcloud
?
2h5
accompanies
anova
dynactin
gtf2h5
invites
keuls
macaques
malfunctioning
nbn1
ndd
ndds
newman
ovx
perimenopausal
presenilin1
proteosome
psen1
rad23a
raphe
scna
serotonin
speculation
subserving
symptomology
ube2d3
ube3a
ubea5
ubiquinase
Tagcloud (Difference)
?
2h5
accompanies
anova
dynactin
gtf2h5
invites
keuls
macaques
malfunctioning
nbn1
ndd
ndds
newman
ovx
perimenopausal
presenilin1
proteosome
psen1
rad23a
raphe
scna
serotonin
speculation
subserving
symptomology
ube2d3
ube3a
ubea5
ubiquinase
Tagcloud (Intersection)
?