HIST1H2AL and BRD7

Number of citations of the paper that reports this interaction (PMID 12489984)
15

Data Source:
HPRD (in vitro)

		HIST1H2AL	BRD7
Gene Name		histone cluster 1, H2al	bromodomain containing 7
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleosome Nucleus Extracellular Vesicular Exosome	Nucleus Cytoplasm
	Molecular Function	DNA Binding Protein Binding Enzyme Binding Protein Heterodimerization Activity	P53 Binding Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Transcription Factor Binding Histone Binding Transcription Regulatory Region DNA Binding Lysine-acetylated Histone Binding
	Biological Process	Biological_process	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Cell Cycle Negative Regulation Of Cell Proliferation Wnt Signaling Pathway Positive Regulation Of Histone Acetylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways		Chromatin modifying enzymes HDACs deacetylate histones Chromatin organization HATs acetylate histones RMTs methylate histone arginines
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: BRD7 CRP GADD45A SAP30 TERF2IP	27 interactors: AGR2 BARD1 BHLHE40 BRD3 BTBD2 DVL1 FTH1 HAP1 HIST1H2AL HIST2H2BE HIST2H3C HIST3H3 HIST4H4 HNRNPUL1 IRF2 LAMA4 LRIF1 NEFL PAFAH1B3 PCBD1 PSMD11 PTPN13 RBFOX2 RIF1 RPLP1 SERPINB9 TRIM24
Entrez ID		8332	29117
HPRD ID		09103	12531
Ensembl ID		ENSG00000198374	ENSG00000166164
Uniprot IDs		A4FTV9 P0C0S8	Q9NPI1
PDB IDs			2I7K
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Reactive Oxygen Species Metabolic Process Negative Regulation Of DNA Recombination At Telomere Negative Regulation Of Cellular Metabolic Process Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Chromosome Organization Protection From Non-homologous End Joining At Telomere Telomere Capping Protein Localization To Chromosome, Telomeric Region Negative Regulation Of Vasodilation Activation Of MAPKKK Activity Positive Regulation Of P38MAPK Cascade Positive Regulation Of Superoxide Anion Generation Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Opsonization Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Superoxide Anion Generation Regulation Of Interleukin-8 Secretion Regulation Of P38MAPK Cascade Regulation Of Metabolic Process Negative Regulation Of Macrophage Derived Foam Cell Differentiation Negative Regulation Of Cell Cycle Negative Regulation Of Lipid Storage Regulation Of Telomere Maintenance RNA-dependent DNA Replication Positive Regulation Of Histone Acetylation Regulation Of Cellular Component Organization Negative Regulation Of DNA Recombination Positive Regulation Of Peptidyl-lysine Acetylation Positive Regulation Of Protein Acetylation Regulation Of Double-strand Break Repair Nucleobase-containing Compound Metabolic Process Protein Localization To Chromosome Response To Lead Ion Telomere Maintenance Via Telomere Lengthening Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Transcription, DNA-templated Acute-phase Response Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process Regulation Of Macrophage Derived Foam Cell Differentiation Regulation Of Vasodilation Regulation Of Histone Acetylation Cellular Response To Calcium Ion Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Intracellular Signal Transduction	Gene Expression Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process RNA Metabolic Process Regulation Of RNA Metabolic Process Retrograde Axon Cargo Transport Transcription, DNA-templated Telomere Maintenance DNA Methylation On Cytosine DNA Modification Chromatin Silencing At RDNA Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Neuromuscular Process Negative Regulation Of Biosynthetic Process Anterograde Axon Cargo Transport Cellular Response To Estrogen Stimulus Chromatin Silencing Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Neurotrophin Production Positive Regulation Of Nonmotile Primary Cilium Assembly Regulation Of Metabolic Process Axon Cargo Transport Regulation Of Gene Expression, Epigenetic Positive Regulation Of Protein Catabolic Process DNA Methylation Demethylation Mucus Secretion Intracellular Sequestering Of Iron Ion Negative Regulation Of MRNA 3'-end Processing Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Homeostatic Process Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Cell Projection Organization Neuromuscular Process Controlling Balance Convergent Extension Involved In Neural Plate Elongation
Tagcloud ?			aza clinically cofactor dc demethylating disturbing ectopic endogenous finding glioma gliomas hypermethylation implicated inactivated inactivation intracranial lrrc4 magnetic microrna mir negatively pathological researches resonance restoration silencing transcriptional transplanted verified
Tagcloud (Difference) ?			aza clinically cofactor dc demethylating disturbing ectopic endogenous finding glioma gliomas hypermethylation implicated inactivated inactivation intracranial lrrc4 magnetic microrna mir negatively pathological researches resonance restoration silencing transcriptional transplanted verified
Tagcloud (Intersection) ?