CAPN2 and PTPRN

Number of citations of the paper that reports this interaction (PMID 11483505)
20

Data Source:
BioGRID (enzymatic study)

		CAPN2	PTPRN
Gene Name		calpain 2, (m/II) large subunit	protein tyrosine phosphatase, receptor type, N
Image
Gene Ontology Annotations	Cellular Component	Chromatin Nucleus Cytoplasm Endoplasmic Reticulum Golgi Apparatus Cytosol Plasma Membrane Focal Adhesion Dendrite Cortical Actin Cytoskeleton Pseudopodium Membrane Raft Extracellular Vesicular Exosome Perinuclear Endoplasmic Reticulum	Integral Component Of Membrane
	Molecular Function	Calcium-dependent Cysteine-type Endopeptidase Activity Calcium Ion Binding Protein Binding Cytoskeletal Protein Binding Cysteine-type Peptidase Activity Protein Heterodimerization Activity	Protein Tyrosine Phosphatase Activity Protein Binding Spectrin Binding GTPase Binding
	Biological Process	Response To Hypoxia Blastocyst Development Proteolysis Myoblast Fusion Protein Autoprocessing Regulation Of Cytoskeleton Organization Proteolysis Involved In Cellular Protein Catabolic Process Cellular Response To Amino Acid Stimulus	Response To Reactive Oxygen Species Protein Dephosphorylation Response To Glucose Cytokine-mediated Signaling Pathway Insulin Secretion Response To Insulin Response To Estrogen Response To CAMP Dense Core Granule Maturation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		17 interactors: ADRBK1 BCL2 BID CAPNS1 CAPNS2 CASP9 CDK5R1 F2RL1 GAS2 KNG1 MAPK1 MAPT NFKBIA NMT1 PTPN1 PTPRN TNS1	13 interactors: CAPN2 CLN8 MADD MAL NOS1 PLP1 PPIA PTPRS PTPRT SNTB2 SNX19 SPTBN4 UBQLN4
Entrez ID		824	5798
HPRD ID		00254	03466
Ensembl ID		ENSG00000162909	ENSG00000054356
Uniprot IDs		B4DN77 P17655 Q59EF6	Q16849 Q96IA0
PDB IDs		1KFU 1KFX 2NQA	2I1Y 2QT7 3N01 3N4W 3NG8 3NP5
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Localization Regulation Of Intracellular Transport Positive Regulation Of Transport Peptidyl-threonine Phosphorylation Apoptotic Process Programmed Cell Death Cell Death Death Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Innate Immune Response Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cell Surface Receptor Signaling Pathway Peptidyl-serine Phosphorylation Defense Response Regulation Of Organelle Organization Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Cellular Component Organization Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Establishment Of Protein Localization Positive Regulation Of Organelle Organization Intrinsic Apoptotic Signaling Pathway Glial Cell Apoptotic Process Positive Regulation Of Mitochondrion Organization Regulation Of Protein Localization Response To Estrogen Neurotrophin TRK Receptor Signaling Pathway Response To Steroid Hormone Immune Response Neurotrophin Signaling Pathway Response To Lipid Intracellular Signal Transduction Regulation Of Immune Response Positive Regulation Of Intracellular Transport Response To Organic Cyclic Compound Enzyme Linked Receptor Protein Signaling Pathway Signal Transduction Regulation Of Cellular Protein Metabolic Process Response To Stress Establishment Of Localization In Cell Pons Development Response To Hormone Regulation Of Apoptotic Process Regulation Of Signal Transduction Regulation Of Mitochondrion Organization Protein Metabolic Process Renal System Process G-protein Coupled Acetylcholine Receptor Signaling Pathway	Myoblast Fusion Central Nervous System Development Syncytium Formation Regulation Of Cellular Protein Metabolic Process Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Adult Walking Behavior Regulation Of Protein Metabolic Process Myotube Differentiation Cell Differentiation Muscle Cell Differentiation Regulation Of Sodium Ion Transport Positive Regulation Of Interleukin-15 Production Positive Regulation Of Adrenergic Receptor Signaling Pathway Involved In Heart Process Positive Regulation Of Chemokine (C-X-C Motif) Ligand 1 Production Cytotoxic T Cell Differentiation TIRAP-dependent Toll-like Receptor 4 Signaling Pathway Uncoating Of Virus Anatomical Structure Development Response To Stimulus Negative Regulation Of Adrenergic Receptor Signaling Pathway Involved In Heart Process Positive Regulation Of Toll-like Receptor 2 Signaling Pathway Dense Core Granule Maturation L-glutamate Uptake Involved In Synaptic Transmission Interaction With Host Spinal Cord Development Adult Locomotory Behavior Positive Regulation Of Adrenergic Receptor Signaling Pathway Negative Regulation Of Adrenergic Receptor Signaling Pathway Positive Regulation Of Toll-like Receptor 3 Signaling Pathway Negative Regulation Of Serotonin Uptake Membrane Raft Polarization Viral Release From Host Cell Developmental Process Muscle Structure Development Signaling Positive Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production Positive Regulation Of The Force Of Heart Contraction Regulation Of Generation Of L-type Calcium Current Cell Communication Regulation Of Neurotransmitter Levels Cell Maturation Myelination Peptidyl-cysteine S-nitrosylation Membrane Raft Localization Axon Ensheathment Regulation Of Adrenergic Receptor Signaling Pathway Age-dependent Response To Oxidative Stress Regulation Of Heart Contraction Adult Behavior Peptidyl-tyrosine Dephosphorylation
Tagcloud ?		1h basilar camk2a camk2b capn1 cisplatin cochlea deacetylases ganglion hair hdacs immunocytochemistry label neurofilament neurotransmitter newborn organotypic ototoxicity panther phalloidin rab3b rhodamine sgns snap25 spiral tnfrsf1a trichostatin tsa vglut1	2j allen atlas b6 bc023892 btg3 bves drd5 edinger egr1 ew ewcp ewpg ghsr housekeeping microdissection neto1 neurogenetic neuropeptides oculomotor peptidergic postn preganglionic projecting publicly punch rcn1 ucn westphal
Tagcloud (Difference) ?		1h basilar camk2a camk2b capn1 cisplatin cochlea deacetylases ganglion hair hdacs immunocytochemistry label neurofilament neurotransmitter newborn organotypic ototoxicity panther phalloidin rab3b rhodamine sgns snap25 spiral tnfrsf1a trichostatin tsa vglut1	2j allen atlas b6 bc023892 btg3 bves drd5 edinger egr1 ew ewcp ewpg ghsr housekeeping microdissection neto1 neurogenetic neuropeptides oculomotor peptidergic postn preganglionic projecting publicly punch rcn1 ucn westphal
Tagcloud (Intersection) ?