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CAPN2
Description
calpain 2
Image
GO Annotations
Cellular Component
Chromatin
Nucleus
Cytoplasm
Lysosome
Endoplasmic Reticulum
Golgi Apparatus
Cytosol
Plasma Membrane
Focal Adhesion
External Side Of Plasma Membrane
Membrane
Dendrite
Cortical Actin Cytoskeleton
Pseudopodium
Cell Projection
Neuronal Cell Body
Membrane Raft
Extracellular Exosome
Perinuclear Endoplasmic Reticulum
Presynapse
Postsynapse
Calpain Complex
Molecular Function
Calcium-dependent Cysteine-type Endopeptidase Activity
Calcium Ion Binding
Protein Binding
Cytoskeletal Protein Binding
Peptidase Activity
Cysteine-type Peptidase Activity
Hydrolase Activity
Enzyme Binding
Protein-containing Complex Binding
Metal Ion Binding
Biological Process
Response To Hypoxia
Blastocyst Development
Proteolysis
Myoblast Fusion
Female Pregnancy
Response To Mechanical Stimulus
Positive Regulation Of Cardiac Muscle Cell Apoptotic Process
Protein Autoprocessing
Protein Catabolic Process
Regulation Of Interleukin-6 Production
Cellular Response To Interferon-beta
Response To Hydrogen Peroxide
Behavioral Response To Pain
Synaptic Vesicle Endocytosis
Regulation Of Cytoskeleton Organization
Proteolysis Involved In Protein Catabolic Process
Cellular Response To Lipopolysaccharide
Cellular Response To Amino Acid Stimulus
Vascular Endothelial Cell Response To Laminar Fluid Shear Stress
Vascular Endothelial Cell Response To Oscillatory Fluid Shear Stress
Protein Catabolic Process At Postsynapse
Positive Regulation Of Myoblast Fusion
Positive Regulation Of Phosphatidylcholine Biosynthetic Process
Pathways
Degradation of the extracellular matrix
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells
Drugs
Diseases
GWAS
Blood protein levels (
30072576
)
Carotenoid levels (alpha-carotene) (
28002826
)
Febrile seizures (MMR vaccine-related) (
25344690
)
Gut microbiota relative abundance (Eubacterium belonging to family Erysipelotrichaceae) (
33208821
)
Waist circumference (
31170924
)
Novel Interacting Genes
1 novel interacting genes:
TUBA4A
Interacting Genes
23 interacting genes:
ATG5
ATXN3
BCL2
BID
CAPNS1
CAPNS2
CASP9
CDK5R1
DUX4
F2RL1
GAS2
GRK2
KCTD7
KNG1
MAPK1
MTDH
NFKBIA
NMT1
PBXIP1
PTPN1
PTPRN
TNS1
ZFYVE21
Entrez ID
824
HPRD ID
00254
Ensembl ID
ENSG00000162909
Uniprot IDs
B4DN77
P17655
Q59EF6
PDB IDs
1KFU
1KFX
2NQA
Enriched GO Terms of Interacting Partners
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Regulation Of Cell Communication
Cytoplasm
Regulation Of Signaling
Cytosol
Epithelial Cell Apoptotic Process
Response To Nutrient Levels
Positive Regulation Of Programmed Cell Death
Cellular Response To Nutrient Levels
Calpain Complex
Lipopolysaccharide-mediated Signaling Pathway
Regulation Of Signal Transduction
B Cell Receptor Signaling Pathway
Vasodilation
Positive Regulation Of Apoptotic Process
Regulation Of Programmed Cell Death
Calcium-dependent Cysteine-type Endopeptidase Activity
Cellular Response To Starvation
Regulation Of Autophagy
Apoptotic Process
Programmed Cell Death
Cell Death
Regulation Of Cell Population Proliferation
Response To Starvation
Pseudopodium
Viral Genome Replication
Regulation Of Biological Quality
G Protein-coupled Acetylcholine Receptor Signaling Pathway
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Peptidyl-threonine Phosphorylation
Neuron Apoptotic Process
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Regulation Of Apoptotic Process
Release Of Cytochrome C From Mitochondria
Protease Binding
Negative Regulation Of Intracellular Signal Transduction
Positive Regulation Of Organelle Organization
Regulation Of Cellular Localization
Cellular Response To Topologically Incorrect Protein
Regulation Of Establishment Of Protein Localization
Protein Phosphatase 2A Binding
Regulation Of Cellular Response To Stress
Ubiquitin Protein Ligase Binding
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Response To Iron Ion
NF-kappaB Binding
Regulation Of Transport
Cellular Response To Stress
Regulation Of Intracellular Signal Transduction
Stem Cell Development
Tagcloud
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