CAPN2 and TNS1

Number of citations of the paper that reports this interaction (PMID 11023826)
9

Data Source:
HPRD (in vitro, in vivo)

		CAPN2	TNS1
Gene Name		calpain 2, (m/II) large subunit	tensin 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Chromatin Nucleus Cytoplasm Endoplasmic Reticulum Golgi Apparatus Cytosol Plasma Membrane Focal Adhesion Dendrite Cortical Actin Cytoskeleton Pseudopodium Membrane Raft Extracellular Vesicular Exosome Perinuclear Endoplasmic Reticulum	Cytoplasm Cytoskeleton Focal Adhesion Cell Surface
	Molecular Function	Calcium-dependent Cysteine-type Endopeptidase Activity Calcium Ion Binding Protein Binding Cytoskeletal Protein Binding Cysteine-type Peptidase Activity Protein Heterodimerization Activity	Actin Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Response To Hypoxia Blastocyst Development Proteolysis Myoblast Fusion Protein Autoprocessing Regulation Of Cytoskeleton Organization Proteolysis Involved In Cellular Protein Catabolic Process Cellular Response To Amino Acid Stimulus	Cell-substrate Junction Assembly Fibroblast Migration
Pathways
Drugs
Diseases
GWAS			Height ( 21998595 20881960) Pulmonary function ( 20010834) Pulmonary function (interaction) ( 23284291)
Protein-Protein Interactions		17 interactors: ADRBK1 BCL2 BID CAPNS1 CAPNS2 CASP9 CDK5R1 F2RL1 GAS2 KNG1 MAPK1 MAPT NFKBIA NMT1 PTPN1 PTPRN TNS1	6 interactors: CAPN2 KLF10 OSGEP PPP1CC PTK2 YWHAZ
Entrez ID		824	7145
HPRD ID		00254	02512
Ensembl ID		ENSG00000162909	ENSG00000079308
Uniprot IDs		B4DN77 P17655 Q59EF6	A1L0S7 E9PGF5 Q59G71 Q86VB0 Q9HBL0
PDB IDs		1KFU 1KFX 2NQA
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Localization Regulation Of Intracellular Transport Positive Regulation Of Transport Peptidyl-threonine Phosphorylation Apoptotic Process Programmed Cell Death Cell Death Death Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Innate Immune Response Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cell Surface Receptor Signaling Pathway Peptidyl-serine Phosphorylation Defense Response Regulation Of Organelle Organization Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Cellular Component Organization Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Establishment Of Protein Localization Positive Regulation Of Organelle Organization Intrinsic Apoptotic Signaling Pathway Glial Cell Apoptotic Process Positive Regulation Of Mitochondrion Organization Regulation Of Protein Localization Response To Estrogen Neurotrophin TRK Receptor Signaling Pathway Response To Steroid Hormone Immune Response Neurotrophin Signaling Pathway Response To Lipid Intracellular Signal Transduction Regulation Of Immune Response Positive Regulation Of Intracellular Transport Response To Organic Cyclic Compound Enzyme Linked Receptor Protein Signaling Pathway Signal Transduction Regulation Of Cellular Protein Metabolic Process Response To Stress Establishment Of Localization In Cell Pons Development Response To Hormone Regulation Of Apoptotic Process Regulation Of Signal Transduction Regulation Of Mitochondrion Organization Protein Metabolic Process Renal System Process G-protein Coupled Acetylcholine Receptor Signaling Pathway	Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Cellular Response To Organonitrogen Compound Regulation Of Circadian Rhythm Cellular Response To Growth Factor Stimulus Response To Growth Factor Threonylcarbamoyladenosine Biosynthetic Process Cellular Response To Organic Substance Circadian Rhythm Response To Organonitrogen Compound Netrin-activated Signaling Pathway Golgi Reassembly Platelet Activation Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Organelle Organization Threonylcarbamoyladenosine Metabolic Process Histamine Secretion By Mast Cell Negative Regulation Of Synapse Assembly Response To Organic Substance Establishment Of Golgi Localization Signal Complex Assembly Golgi Inheritance Histamine Secretion Rhythmic Process Protein Autoprocessing Establishment Of Organelle Localization Cellular Response To Peptide Histamine Transport Golgi Localization Adenosine Metabolic Process Negative Regulation Of Anoikis Organelle Localization Establishment Of Nucleus Localization Blood Coagulation Regulation Of Anoikis Hemostasis Mast Cell Degranulation Response To Stress Production Of Molecular Mediator Involved In Inflammatory Response Triglyceride Catabolic Process Myoblast Fusion Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Entrainment Of Circadian Clock By Photoperiod Response To Peptide Mast Cell Mediated Immunity Cellular Metabolic Process Growth Hormone Receptor Signaling Pathway Regulation Of Cytoskeleton Organization
Tagcloud ?		1h basilar camk2a camk2b capn1 cisplatin cochlea deacetylases ganglion hair hdacs immunocytochemistry label neurofilament neurotransmitter newborn organotypic ototoxicity panther phalloidin rab3b rhodamine sgns snap25 spiral tnfrsf1a trichostatin tsa vglut1	aberration aberrations algorithms cgh characterised cin coca confirms crc custom deleted deletions driver fmcr gained gains hybridisation ifnar1 ifnar2 kcnma1 microsatellite mss nfkbia oncogenes prdm16 rassf3 rpa3 scna silico
Tagcloud (Difference) ?		1h basilar camk2a camk2b capn1 cisplatin cochlea deacetylases ganglion hair hdacs immunocytochemistry label neurofilament neurotransmitter newborn organotypic ototoxicity panther phalloidin rab3b rhodamine sgns snap25 spiral tnfrsf1a trichostatin tsa vglut1	aberration aberrations algorithms cgh characterised cin coca confirms crc custom deleted deletions driver fmcr gained gains hybridisation ifnar1 ifnar2 kcnma1 microsatellite mss nfkbia oncogenes prdm16 rassf3 rpa3 scna silico
Tagcloud (Intersection) ?