HOMEZ and MRPL11

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		HOMEZ	MRPL11
Gene Name		homeobox and leucine zipper encoding	mitochondrial ribosomal protein L11
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm	Mitochondrial Inner Membrane Mitochondrial Ribosome
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity	Structural Constituent Of Ribosome Protein Binding Poly(A) RNA Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated	Translation Organelle Organization Mitochondrial Translation Mitochondrial Translational Initiation Mitochondrial Translational Elongation Mitochondrial Translational Termination
Pathways			Mitochondrial translation Organelle biogenesis and maintenance Mitochondrial translation elongation Mitochondrial translation initiation Mitochondrial translation termination
Drugs
Diseases
GWAS			Bipolar disorder ( 21926972)
Protein-Protein Interactions		31 interactors: AEN AES APITD1 DEF6 DGCR6 DNTTIP1 EBF1 EIF4E2 GRB2 HOXC8 KPNA2 LNX1 LRRC7 MAD2L1BP MED18 MRPL11 NCK2 PIN1 PRKAA1 PRKAA2 RBM39 RNF8 RPL9 SDCBP SH3RF2 SMYD1 SNRPB2 SUMO2 TCEB3 TRAF4 ZBTB7A	15 interactors: APP CAMK2B CAMK2D CRYAB FSD2 HMBOX1 HOMEZ JAKMIP2 KRT40 PNMA1 SLC16A9 TAX1BP1 TFCP2 THAP1 VPS52
Entrez ID		57594	65003
HPRD ID		12167	14739
Ensembl ID		ENSG00000215271	ENSG00000174547
Uniprot IDs		F8WCA3 Q8IX15	Q9Y3B7
PDB IDs		2ECC 2YS9
Enriched GO Terms of Interacting Partners?		Regulation Of Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Response To Ionizing Radiation RNA Metabolic Process Transcription, DNA-templated Nitrogen Compound Metabolic Process Regulation Of Energy Homeostasis Positive Regulation Of Glycolytic Process Negative Regulation Of Cellular Metabolic Process Fatty Acid Homeostasis Biosynthetic Process Histone-serine Phosphorylation Positive Regulation Of Metabolic Process Cellular Response To Glucose Starvation Regulation Of Glycolytic Process Regulation Of Cellular Process Chromatin Modification Negative Regulation Of TOR Signaling Protein Modification By Small Protein Conjugation Regulation Of MAPK Cascade Histone Exchange Cholesterol Biosynthetic Process Insulin Receptor Signaling Pathway Positive Regulation Of Autophagy Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Cellular Protein Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Biosynthetic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Histone Phosphorylation Translational Elongation Histone Modification Sterol Biosynthetic Process Negative Regulation Of Glucosylceramide Biosynthetic Process Cold Acclimation Regulation Of RNA Metabolic Process Anion Homeostasis Chromatin Remodeling	Regulation Of Cellular Response To Heat Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Immune Response Defense Response Cellular Response To Heat Innate Immune Response Inhibitory G-protein Coupled Receptor Phosphorylation Neuromuscular Process Controlling Balance Developmental Cell Growth Regulation Of Cell Cycle Regulation Of Synapse Structure Or Activity Regulation Of Mitotic Cell Cycle Synaptic Growth At Neuromuscular Junction Activation Of Meiosis Involved In Egg Activation Embryonic Ectodermal Digestive Tract Development Response To Heat Response To Inorganic Substance Collateral Sprouting In Absence Of Injury Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction Cardiac Muscle Cell Contraction Response To Abiotic Stimulus Peptidyl-serine Phosphorylation Regulation Of Cell Cycle Process Interferon-gamma-mediated Signaling Pathway Neuromuscular Process Regulation Of Generation Of L-type Calcium Current Activation Of Meiosis Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Collateral Sprouting Axon Midline Choice Point Recognition Positive Regulation Of Rac Protein Signal Transduction Regulation Of Histone Deacetylase Activity Cellular Response To Interferon-gamma Cell Growth Regulation Of RNA Metabolic Process Immune System Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Ectodermal Cell Differentiation Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Regulation Of Growth Response To Interferon-gamma Axon Choice Point Recognition Negative Regulation Of Sodium Ion Transmembrane Transport Regulation Of Relaxation Of Cardiac Muscle Regulation Of Synaptic Transmission, Cholinergic
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