HOMEZ and MED18

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		HOMEZ	MED18
Gene Name		homeobox and leucine zipper encoding	mediator complex subunit 18
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm	Mediator Complex
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity	RNA Polymerase II Transcription Cofactor Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter
Pathways			PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-Protein Interactions		31 interactors: AEN AES APITD1 DEF6 DGCR6 DNTTIP1 EBF1 EIF4E2 GRB2 HOXC8 KPNA2 LNX1 LRRC7 MAD2L1BP MED18 MRPL11 NCK2 PIN1 PRKAA1 PRKAA2 RBM39 RNF8 RPL9 SDCBP SH3RF2 SMYD1 SNRPB2 SUMO2 TCEB3 TRAF4 ZBTB7A	8 interactors: CAMK2B HOMEZ MED20 MED31 MED9 THOC7 TRIM39 USP49
Entrez ID		57594	54797
HPRD ID		12167	17476
Ensembl ID		ENSG00000215271	ENSG00000130772
Uniprot IDs		F8WCA3 Q8IX15	B4DJL3 Q9BUE0
PDB IDs		2ECC 2YS9
Enriched GO Terms of Interacting Partners?		Regulation Of Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Response To Ionizing Radiation RNA Metabolic Process Transcription, DNA-templated Nitrogen Compound Metabolic Process Regulation Of Energy Homeostasis Positive Regulation Of Glycolytic Process Negative Regulation Of Cellular Metabolic Process Fatty Acid Homeostasis Biosynthetic Process Histone-serine Phosphorylation Positive Regulation Of Metabolic Process Cellular Response To Glucose Starvation Regulation Of Glycolytic Process Regulation Of Cellular Process Chromatin Modification Negative Regulation Of TOR Signaling Protein Modification By Small Protein Conjugation Regulation Of MAPK Cascade Histone Exchange Cholesterol Biosynthetic Process Insulin Receptor Signaling Pathway Positive Regulation Of Autophagy Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Cellular Protein Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Biosynthetic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Histone Phosphorylation Translational Elongation Histone Modification Sterol Biosynthetic Process Negative Regulation Of Glucosylceramide Biosynthetic Process Cold Acclimation Regulation Of RNA Metabolic Process Anion Homeostasis Chromatin Remodeling	RNA Metabolic Process Gene Expression Inhibitory G-protein Coupled Receptor Phosphorylation Histone H2B Conserved C-terminal Lysine Deubiquitination Activation Of Meiosis Involved In Egg Activation Nucleobase-containing Compound Metabolic Process Cellular Metabolic Process Heterocycle Metabolic Process Activation Of Meiosis Cellular Aromatic Compound Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Synaptic Transmission, Cholinergic Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Viral MRNA Export From Host Cell Nucleus Nitrogen Compound Metabolic Process Negative Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Skeletal Muscle Adaptation Regulation Of Synapse Structural Plasticity Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Dendritic Spine Morphogenesis RNA Splicing Positive Regulation Of Synapse Maturation Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of Meiotic Nuclear Division Histone Deubiquitination Egg Activation Regulation Of Synapse Maturation Regulation Of Protein Catabolic Process MRNA Processing Positive Regulation Of Dendritic Spine Development Intracellular Transport Of Virus Regulation Of Cellular Response To Heat Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Dendritic Spine Morphogenesis
Tagcloud ?			aba abscisic arabidopsis associates conveys cues deregulated engender evolutionarily flowering frigida4 glutaredoxins grx480 grxs13 h5 insensitive mediator multifunctional occupancy reinforcing termination terminator thioredoxin tri trx underpinning yang1 yin yy1
Tagcloud (Difference) ?			aba abscisic arabidopsis associates conveys cues deregulated engender evolutionarily flowering frigida4 glutaredoxins grx480 grxs13 h5 insensitive mediator multifunctional occupancy reinforcing termination terminator thioredoxin tri trx underpinning yang1 yin yy1
Tagcloud (Intersection) ?