HOMEZ and SH3RF2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		HOMEZ	SH3RF2
Gene Name		homeobox and leucine zipper encoding	SH3 domain containing ring finger 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm	Nucleoplasm
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity	Protein Phosphatase Inhibitor Activity Protein Binding Protein Phosphatase 1 Binding Zinc Ion Binding Ligase Activity Phosphatase Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated	Negative Regulation Of Phosphatase Activity Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		31 interactors: AEN AES APITD1 DEF6 DGCR6 DNTTIP1 EBF1 EIF4E2 GRB2 HOXC8 KPNA2 LNX1 LRRC7 MAD2L1BP MED18 MRPL11 NCK2 PIN1 PRKAA1 PRKAA2 RBM39 RNF8 RPL9 SDCBP SH3RF2 SMYD1 SNRPB2 SUMO2 TCEB3 TRAF4 ZBTB7A	14 interactors: AMOTL2 APP BANP FASLG GOLGA2 HOMEZ LZTS2 MTUS2 PAK4 PPP1CA PPP1CC RBPMS SPERT UBE2N
Entrez ID		57594	153769
HPRD ID		12167	10229
Ensembl ID		ENSG00000215271	ENSG00000156463
Uniprot IDs		F8WCA3 Q8IX15	Q08AM8 Q8TEC5
PDB IDs		2ECC 2YS9
Enriched GO Terms of Interacting Partners?		Regulation Of Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Response To Ionizing Radiation RNA Metabolic Process Transcription, DNA-templated Nitrogen Compound Metabolic Process Regulation Of Energy Homeostasis Positive Regulation Of Glycolytic Process Negative Regulation Of Cellular Metabolic Process Fatty Acid Homeostasis Biosynthetic Process Histone-serine Phosphorylation Positive Regulation Of Metabolic Process Cellular Response To Glucose Starvation Regulation Of Glycolytic Process Regulation Of Cellular Process Chromatin Modification Negative Regulation Of TOR Signaling Protein Modification By Small Protein Conjugation Regulation Of MAPK Cascade Histone Exchange Cholesterol Biosynthetic Process Insulin Receptor Signaling Pathway Positive Regulation Of Autophagy Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Cellular Protein Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Biosynthetic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Histone Phosphorylation Translational Elongation Histone Modification Sterol Biosynthetic Process Negative Regulation Of Glucosylceramide Biosynthetic Process Cold Acclimation Regulation Of RNA Metabolic Process Anion Homeostasis Chromatin Remodeling	Triglyceride Catabolic Process Entrainment Of Circadian Clock By Photoperiod Photoperiodism Entrainment Of Circadian Clock Acylglycerol Catabolic Process Regulation Of Signal Transduction Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Signaling Cell Surface Receptor Signaling Pathway Cell Cycle Glycogen Metabolic Process Response To Light Stimulus Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Gene Expression Circadian Regulation Of Gene Expression Regulation Of ERBB Signaling Pathway Polysaccharide Metabolic Process Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Synaptic Growth At Neuromuscular Junction Triglyceride Metabolic Process Regulation Of Circadian Rhythm Cell Division Signal Transduction Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Response To Radiation Neutral Lipid Metabolic Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Collateral Sprouting In Absence Of Injury Endosomal Lumen Acidification Positive Regulation Of Cellular Protein Metabolic Process Signaling Retinal Cell Programmed Cell Death Regulation Of Histone Ubiquitination Cell Communication Energy Reserve Metabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Protein Binding Collateral Sprouting Axon Midline Choice Point Recognition Positive Regulation Of Peptidase Activity Positive Regulation Of Protein Metabolic Process Cellular Lipid Catabolic Process Cell Growth Positive Regulation Of Signal Transduction Regulation Of Protein Metabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Necroptotic Signaling Pathway Response To Growth Factor
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