Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
SHARPIN and TXN2
Number of citations of the paper that reports this interaction (PMID
21988832
)
14
Data Source:
BioGRID
(two hybrid)
SHARPIN
TXN2
Gene Name
SHANK-associated RH domain interactor
thioredoxin 2
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Postsynaptic Density
Cell Junction
Dendrite
LUBAC Complex
Nucleolus
Mitochondrion
Mitochondrial Matrix
Dendrite
Neuronal Cell Body
Molecular Function
Protein Binding
Zinc Ion Binding
Polyubiquitin Binding
Protein Complex Binding
Identical Protein Binding
Peptide-methionine (S)-S-oxide Reductase Activity
Protein Disulfide Oxidoreductase Activity
Protein Complex Binding
Peptide-methionine (R)-S-oxide Reductase Activity
Biological Process
Mitochondrion Organization
Brain Development
Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Apoptotic Nuclear Changes
Keratinization
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of Inflammatory Response
Protein Homooligomerization
Protein Linear Polyubiquitination
Regulation Of CD40 Signaling Pathway
Response To Reactive Oxygen Species
Response To Hypoxia
Glycerol Ether Metabolic Process
Response To Nutrient
Response To Hormone
Response To Glucose
Response To Organic Cyclic Compound
Cellular Response To Nutrient Levels
Response To Drug
Cell Redox Homeostasis
Response To Axon Injury
Oxidation-reduction Process
Pathways
Detoxification of Reactive Oxygen Species
Drugs
Diseases
GWAS
Protein-Protein Interactions
10 interactors:
ITGA1
ITGA2
ITGAD
ITGAL
ITGAM
SHANK1
SHANK2
TXN2
UBC
UBE2D3
34 interactors:
AGTRAP
ALDOB
AP2B1
CCDC114
DCTD
FAM9B
GPRASP2
KRT18
KRT40
MAGEA11
MAPRE2
MAPRE3
MLH1
MRFAP1L1
MTUS2
PPCDC
PSME3
RABAC1
RABGEF1
RBM45
REEP6
RPIA
SCYL3
SHARPIN
SSNA1
STUB1
THAP1
TIFA
TRIM21
TRIP6
UCHL5
VIM
VPS52
ZBTB14
Entrez ID
81858
25828
HPRD ID
15463
07161
Ensembl ID
ENSG00000179526
ENSG00000100348
Uniprot IDs
Q6PJD5
Q9H0F6
B4DX69
Q99757
PDB IDs
4EMO
1UVZ
1W4V
1W89
Enriched GO Terms of Interacting Partners
?
Integrin-mediated Signaling Pathway
Activated T Cell Proliferation
Extracellular Matrix Organization
Extracellular Structure Organization
T Cell Proliferation
Toll-like Receptor 4 Signaling Pathway
Response To Hypoxia
Response To Wounding
Toll-like Receptor Signaling Pathway
Lymphocyte Proliferation
Mononuclear Cell Proliferation
Leukocyte Proliferation
Positive Regulation Of Immune System Process
Vocalization Behavior
Blood Coagulation
Pattern Recognition Receptor Signaling Pathway
Hemostasis
Innate Immune Response-activating Signal Transduction
Cell Communication
Activation Of Innate Immune Response
Cell-matrix Adhesion
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Positive Regulation Of Innate Immune Response
Cell Surface Receptor Signaling Pathway
Cell Adhesion
Cellular Extravasation
Regulation Of Body Fluid Levels
Positive Regulation Of Phosphatase Activity
Wound Healing
Cell-substrate Adhesion
Immune System Process
Immune Response
Regulation Of Immune System Process
Leukocyte Migration
Response To Stress
Regulation Of Innate Immune Response
Social Behavior
Cell Proliferation
Negative Regulation Of Type I Interferon Production
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Positive Regulation Of Dephosphorylation
Negative Regulation Of ERBB Signaling Pathway
T Cell Aggregation
T Cell Activation
Lymphocyte Aggregation
Leukocyte Aggregation
Neutrophil Chemotaxis
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Neutrophil Migration
Regulation Of DNA-templated Transcription In Response To Stress
Protein Polyubiquitination
Cell Cycle
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Intermediate Filament Cytoskeleton Organization
Intermediate Filament-based Process
Protein Autoubiquitination
Negative Regulation Of Kit Signaling Pathway
Meiotic Metaphase I Plate Congression
Golgi To Plasma Membrane CFTR Protein Transport
Meiotic Spindle Midzone Assembly
Regulation Of Proteasomal Protein Catabolic Process
I-kappaB Kinase/NF-kappaB Signaling
Signal Transduction
Cellular Component Disassembly Involved In Execution Phase Of Apoptosis
Positive Regulation Of Chaperone-mediated Protein Complex Assembly
Negative Regulation Of Mitotic Recombination
Positive Regulation Of Microtubule Plus-end Binding
Fructose Catabolic Process
Embryonic Ectodermal Digestive Tract Development
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Viral Process
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Positive Regulation Of Ubiquitin-protein Transferase Activity
Execution Phase Of Apoptosis
Nucleotide Metabolic Process
Positive Regulation Of Ligase Activity
Negative Regulation Of Protein Deubiquitination
Regulation Of CD40 Signaling Pathway
Protein Linear Polyubiquitination
Positive Regulation Of Cell Cycle
Apoptotic Process
Signaling
Nicotinamide Nucleotide Metabolic Process
Regulation Of Ubiquitin-protein Transferase Activity
Regulation Of Mitotic Recombination
Pentose-phosphate Shunt, Non-oxidative Branch
Fructose 1,6-bisphosphate Metabolic Process
Male Meiosis Chromosome Segregation
Positive Regulation Of Viral Entry Into Host Cell
Programmed Cell Death
Cell Communication
Protein Complex Assembly
Cell Cycle Process
Regulation Of Cytokine-mediated Signaling Pathway
Cell Death
Nucleobase-containing Small Molecule Metabolic Process
Death
Negative Regulation Of Interleukin-6 Secretion
Ciliary Receptor Clustering Involved In Smoothened Signaling Pathway
Tagcloud
?
1l
chain
composed
conjugation
consists
deeply
elusive
fluorescein
fret
fungal
gliotoxin
hoil
hoip
hts
ibr
linear
lubac
malignancy
metabolite
modulator
nemo
ring
searched
selectively
tb3
termini
though
throughput
ubiquitin
Tagcloud (Difference)
?
1l
chain
composed
conjugation
consists
deeply
elusive
fluorescein
fret
fungal
gliotoxin
hoil
hoip
hts
ibr
linear
lubac
malignancy
metabolite
modulator
nemo
ring
searched
selectively
tb3
termini
though
throughput
ubiquitin
Tagcloud (Intersection)
?