TXN2 and VPS52

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TXN2	VPS52
Gene Name		thioredoxin 2	vacuolar protein sorting 52 homolog (S. cerevisiae)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleolus Mitochondrion Mitochondrial Matrix Dendrite Neuronal Cell Body	Golgi Apparatus Endosome Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Peptide-methionine (S)-S-oxide Reductase Activity Protein Disulfide Oxidoreductase Activity Protein Complex Binding Peptide-methionine (R)-S-oxide Reductase Activity	Protein Binding Syntaxin Binding
	Biological Process	Response To Reactive Oxygen Species Response To Hypoxia Glycerol Ether Metabolic Process Response To Nutrient Response To Hormone Response To Glucose Response To Organic Cyclic Compound Cellular Response To Nutrient Levels Response To Drug Cell Redox Homeostasis Response To Axon Injury Oxidation-reduction Process	Ectodermal Cell Differentiation Protein Transport Embryonic Ectodermal Digestive Tract Development
Pathways		Detoxification of Reactive Oxygen Species
Drugs
Diseases
GWAS
Protein-Protein Interactions		34 interactors: AGTRAP ALDOB AP2B1 CCDC114 DCTD FAM9B GPRASP2 KRT18 KRT40 MAGEA11 MAPRE2 MAPRE3 MLH1 MRFAP1L1 MTUS2 PPCDC PSME3 RABAC1 RABGEF1 RBM45 REEP6 RPIA SCYL3 SHARPIN SSNA1 STUB1 THAP1 TIFA TRIM21 TRIP6 UCHL5 VIM VPS52 ZBTB14	49 interactors: AAMP ARNT2 ATP6V1D C1orf109 CACNA1A CCDC146 CCDC33 DDX6 EPM2AIP1 FAM184A GFM2 GOLGA1 HAUS1 HEATR1 KANK2 KIAA1217 KIF5B KLC3 LMO4 MAPK3 METTL13 MFAP1 MRPL11 NFKBIB NOP2 PPP1R18 PRKAA1 PRKAA2 RAB4A RNF41 SH2D4A STX11 TBC1D22B TCEANC TEAD4 THAP11 TPM3 TRAF6 TSSK3 TSTD2 TXLNA TXN2 USP2 VPS28 VPS51 VPS53 VPS54 WTAP ZMAT2
Entrez ID		25828	6293
HPRD ID		07161	09142
Ensembl ID		ENSG00000100348	ENSG00000223501
Uniprot IDs		B4DX69 Q99757	B4DNI9 Q8N1B4
PDB IDs		1UVZ 1W4V 1W89
Enriched GO Terms of Interacting Partners?		Protein Polyubiquitination Cell Cycle Protein Ubiquitination Protein Modification By Small Protein Conjugation Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Protein Autoubiquitination Negative Regulation Of Kit Signaling Pathway Meiotic Metaphase I Plate Congression Golgi To Plasma Membrane CFTR Protein Transport Meiotic Spindle Midzone Assembly Regulation Of Proteasomal Protein Catabolic Process I-kappaB Kinase/NF-kappaB Signaling Signal Transduction Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Positive Regulation Of Chaperone-mediated Protein Complex Assembly Negative Regulation Of Mitotic Recombination Positive Regulation Of Microtubule Plus-end Binding Fructose Catabolic Process Embryonic Ectodermal Digestive Tract Development Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Viral Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Ubiquitin-protein Transferase Activity Execution Phase Of Apoptosis Nucleotide Metabolic Process Positive Regulation Of Ligase Activity Negative Regulation Of Protein Deubiquitination Regulation Of CD40 Signaling Pathway Protein Linear Polyubiquitination Positive Regulation Of Cell Cycle Apoptotic Process Signaling Nicotinamide Nucleotide Metabolic Process Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Mitotic Recombination Pentose-phosphate Shunt, Non-oxidative Branch Fructose 1,6-bisphosphate Metabolic Process Male Meiosis Chromosome Segregation Positive Regulation Of Viral Entry Into Host Cell Programmed Cell Death Cell Communication Protein Complex Assembly Cell Cycle Process Regulation Of Cytokine-mediated Signaling Pathway Cell Death Nucleobase-containing Small Molecule Metabolic Process Death Negative Regulation Of Interleukin-6 Secretion Ciliary Receptor Clustering Involved In Smoothened Signaling Pathway	Anion Homeostasis Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Establishment Of Localization In Cell Insulin Receptor Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Response To Insulin Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Regulation Of Energy Homeostasis TRIF-dependent Toll-like Receptor Signaling Pathway Autophagy Cellular Localization Retrograde Transport, Endosome To Golgi Positive Regulation Of Glycolytic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Intracellular Transport MyD88-dependent Toll-like Receptor Signaling Pathway Fatty Acid Homeostasis Regulation Of Generation Of Precursor Metabolites And Energy Toll-like Receptor 4 Signaling Pathway Interleukin-1-mediated Signaling Pathway Endosomal Transport Cellular Response To Insulin Stimulus Gene Expression Regulation Of Circadian Rhythm Histone-serine Phosphorylation Cellular Response To Glucose Starvation Toll-like Receptor Signaling Pathway RNA Metabolic Process Regulation Of Glycolytic Process Response To Peptide Hormone Response To Hormone Negative Regulation Of TOR Signaling Response To Peptide Cholesterol Biosynthetic Process Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Cerebellar Molecular Layer Development Negative Regulation Of Apolipoprotein Binding Negative Regulation Of Glucosylceramide Biosynthetic Process Cold Acclimation Positive Regulation Of Autophagy Activation Of MAPK Activity Activation Of Innate Immune Response Organelle Disassembly Cellular Response To Peptide Hormone Stimulus Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Tagcloud ?			biosynthetic buildup cargo cathepsin correspond cycling endosomes explaining garp hydrolase hydrolases impairs intermediates lysosomes missorting mprs recycling relies retrograde shiga sorting swollen tgn tgn46 undegraded vesicles vps53 vps54 wobbler
Tagcloud (Difference) ?			biosynthetic buildup cargo cathepsin correspond cycling endosomes explaining garp hydrolase hydrolases impairs intermediates lysosomes missorting mprs recycling relies retrograde shiga sorting swollen tgn tgn46 undegraded vesicles vps53 vps54 wobbler
Tagcloud (Intersection) ?