TXN2 and STN1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TXN2	STN1
Description		thioredoxin 2	STN1 subunit of CST complex
Image
GO Annotations	Cellular Component	Nucleolus Mitochondrion Mitochondrial Matrix	Chromosome, Telomeric Region Fibrillar Center Nucleus Nucleoplasm Chromosome Intermediate Filament Cytoskeleton CST Complex
	Molecular Function	Protein Binding Protein-disulfide Reductase Activity	Nucleic Acid Binding DNA Binding Single-stranded DNA Binding Protein Binding Telomeric DNA Binding Single-stranded Telomeric DNA Binding
	Biological Process	Cell Redox Homeostasis	Telomere Maintenance Telomere Maintenance Via Telomere Lengthening Telomere Capping Negative Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of DNA Replication Regulation Of DNA Metabolic Process
Pathways		Degradation of cysteine and homocysteine Detoxification of Reactive Oxygen Species	Polymerase switching on the C-strand of the telomere Telomere C-strand synthesis initiation
Drugs
Diseases
GWAS			Chronic obstructive pulmonary disease ( 30804561) Leukocyte telomere length ( 32109421) Myocardial infarction ( 33532862) Systemic lupus erythematosus ( 33272962) Telomere length ( 33941849) Uterine fibroids ( 30194396 31488892) White matter integrity (mean diffusivity) ( 32358547)
Interacting Genes		78 interacting genes: ABI3 AGTRAP ALDOB ANKRD36B AP2B1 BCAS2 CCDC197 CDCA4 CEP70 CGGBP1 CHMP1A CIB4 CRACR2B CSTPP1 DCTD DDIT3 ETHE1 FAM9B FHL5 GOLGA6L9 GPRASP2 GPRASP3 GTPBP2 GUCD1 HAUS1 HAUS8 KAZN KRT18 KRT27 KRT40 LCN2 MAGEA11 MAGEA4 MAGEB2 MAPRE2 MAPRE3 MDFI MEOX2 MIPOL1 MLH1 MRFAP1 MRFAP1L1 MTUS2 MYL9 NUTM1 ODAD1 PEX19 POMC PPCDC PPP1R16B PSME3 RABAC1 RABGEF1 RBM45 REEP6 RPIA SAT1 SCYL3 SHARPIN SPTA1 SSNA1 STN1 STUB1 SYCE1 TFIP11 THAP1 TIFA TMOD4 TRIM21 TRIP6 TTC32 UCHL5 UQCC2 VIM VPS52 ZBTB14 ZMYND12 ZSCAN32	18 interacting genes: AIRIM APP C14orf119 CDK3 GOLGA2 LRRK2 MFHAS1 MKRN3 MVP NTAQ1 RCOR3 TEN1 TOLLIP TPP1 TRIML2 TUBGCP4 TXN2 ZDHHC17
Entrez ID		25828	79991
HPRD ID		07161	14872
Ensembl ID		ENSG00000100348	ENSG00000107960
Uniprot IDs		Q99757	Q9H668
PDB IDs		1UVZ 1W4V 1W89	4JOI 4JQF 6W6W 7U5C 8D0B 8D0K 8SOJ 8SOK
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Protein Binding Microtubule Organizing Center Organelle Organization Cytoskeleton Organization Cytoskeleton Membraneless Organelle Assembly Spindle Assembly Regulation Of Microtubule Cytoskeleton Organization Spindle Organization Synaptonemal Complex Microtubule Cytoskeleton Organization Cytoplasm Microtubule-based Process	Golgi-associated Vesicle Protein Metabolic Process Cellular Response To Catecholamine Stimulus Cellular Response To Manganese Ion Response To Catecholamine Response To Manganese Ion Amyloid-beta Complex Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Growth Cone Lamellipodium Regulation Of Toll-like Receptor Signaling Pathway Regulation Of Response To Calcium Ion Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Recycling Endosome Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of CAMP/PKA Signal Transduction Negative Regulation Of Notch Signaling Pathway Microtubule Nucleation Perforant Pathway To Dendrate Granule Cell Synapse Protein-N-terminal Glutamine Amidohydrolase Activity Cellular Response To Curcumin Caveola Neck GTP-dependent Protein Kinase Activity Wnt Signalosome Assembly Negative Regulation Of Protein Localization To Nucleus
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?