TXN2 and RBM45

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		TXN2	RBM45
Description		thioredoxin 2	RNA binding motif protein 45
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GO Annotations	Cellular Component	Nucleolus Mitochondrion Mitochondrial Matrix	Nucleus Nucleoplasm Cytoplasm Ribonucleoprotein Complex
	Molecular Function	Protein Binding Protein-disulfide Reductase Activity	Nucleic Acid Binding RNA Binding Protein Binding Identical Protein Binding
	Biological Process	Cell Redox Homeostasis	Nervous System Development Cell Differentiation
Pathways		Degradation of cysteine and homocysteine Detoxification of Reactive Oxygen Species
Drugs
Diseases
GWAS			Refractive error ( 32231278)
Interacting Genes		78 interacting genes: ABI3 AGTRAP ALDOB ANKRD36B AP2B1 BCAS2 CCDC197 CDCA4 CEP70 CGGBP1 CHMP1A CIB4 CRACR2B CSTPP1 DCTD DDIT3 ETHE1 FAM9B FHL5 GOLGA6L9 GPRASP2 GPRASP3 GTPBP2 GUCD1 HAUS1 HAUS8 KAZN KRT18 KRT27 KRT40 LCN2 MAGEA11 MAGEA4 MAGEB2 MAPRE2 MAPRE3 MDFI MEOX2 MIPOL1 MLH1 MRFAP1 MRFAP1L1 MTUS2 MYL9 NUTM1 ODAD1 PEX19 POMC PPCDC PPP1R16B PSME3 RABAC1 RABGEF1 RBM45 REEP6 RPIA SAT1 SCYL3 SHARPIN SPTA1 SSNA1 STN1 STUB1 SYCE1 TFIP11 THAP1 TIFA TMOD4 TRIM21 TRIP6 TTC32 UCHL5 UQCC2 VIM VPS52 ZBTB14 ZMYND12 ZSCAN32	16 interacting genes: ALX1 FANCL FXR1 FXR2 MEMO1 MIR15B MIR200A MIR205 MIR25 MIR29A MIR34B NTAQ1 OGT TNPO2 TRAF1 TXN2
Entrez ID		25828	129831
HPRD ID		07161	09927
Ensembl ID		ENSG00000100348	ENSG00000155636
Uniprot IDs		Q99757	Q8IUH3
PDB IDs		1UVZ 1W4V 1W89	7CSX 7CSZ 8WQ3 8WQ5
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Protein Binding Microtubule Organizing Center Organelle Organization Cytoskeleton Organization Cytoskeleton Membraneless Organelle Assembly Spindle Assembly Regulation Of Microtubule Cytoskeleton Organization Spindle Organization Synaptonemal Complex Microtubule Cytoskeleton Organization Cytoplasm Microtubule-based Process	MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression MRNA 3'-UTR Binding Regulatory NcRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing RISC Complex Negative Regulation Of Gene Expression Negative Regulation Of Translation Regulation Of Translation Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Negative Regulation Of Vasculature Development Negative Regulation Of Angiogenesis Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Positive Regulation Of Translation Negative Regulation Of Developmental Process MiRNA-mediated Gene Silencing By Inhibition Of Translation Regulation Of Developmental Process Positive Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Endothelial Cell Migration Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Connective Tissue Replacement Negative Regulation Of Multicellular Organismal Process Negative Regulation Of Metabolic Process Negative Regulation Of Vascular Endothelial Growth Factor Production Regulation Of Connective Tissue Replacement MRNA Destabilization RNA Destabilization Translation Regulator Activity Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Positive Regulation Of MRNA Catabolic Process Positive Regulation Of Tissue Remodeling Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Protein Metabolic Process Regulation Of Multicellular Organismal Development Regulation Of Angiogenesis Negative Regulation Of Cell Migration Regulation Of Vasculature Development Negative Regulation Of Amyloid-beta Formation Dentate Gyrus Development Regulation Of Long-term Neuronal Synaptic Plasticity Negative Regulation Of Cell Motility Negative Regulation Of Amyloid Precursor Protein Catabolic Process Positive Regulation Of MRNA Metabolic Process Negative Regulation Of Locomotion Regulation Of Endothelial Cell Proliferation Regulation Of Vascular Endothelial Cell Proliferation Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
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