TXN2 and SCYL3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TXN2	SCYL3
Description		thioredoxin 2	SCY1 like pseudokinase 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleolus Mitochondrion Mitochondrial Matrix	Golgi Membrane Cytoplasm Endoplasmic Reticulum Golgi Apparatus Cytosol Lamellipodium Cell Projection
	Molecular Function	Protein Binding Protein-disulfide Reductase Activity	Protein Binding ATP Binding Kinase Activity Identical Protein Binding
	Biological Process	Cell Redox Homeostasis	Inflammatory Response Intracellular Protein Localization Cell Migration Spinal Cord Motor Neuron Differentiation Neuron Development
Pathways		Degradation of cysteine and homocysteine Detoxification of Reactive Oxygen Species
Drugs
Diseases
GWAS			Acute anterior uveitis in ankylosing spondylitis ( 32492107)
Interacting Genes		78 interacting genes: ABI3 AGTRAP ALDOB ANKRD36B AP2B1 BCAS2 CCDC197 CDCA4 CEP70 CGGBP1 CHMP1A CIB4 CRACR2B CSTPP1 DCTD DDIT3 ETHE1 FAM9B FHL5 GOLGA6L9 GPRASP2 GPRASP3 GTPBP2 GUCD1 HAUS1 HAUS8 KAZN KRT18 KRT27 KRT40 LCN2 MAGEA11 MAGEA4 MAGEB2 MAPRE2 MAPRE3 MDFI MEOX2 MIPOL1 MLH1 MRFAP1 MRFAP1L1 MTUS2 MYL9 NUTM1 ODAD1 PEX19 POMC PPCDC PPP1R16B PSME3 RABAC1 RABGEF1 RBM45 REEP6 RPIA SAT1 SCYL3 SHARPIN SPTA1 SSNA1 STN1 STUB1 SYCE1 TFIP11 THAP1 TIFA TMOD4 TRIM21 TRIP6 TTC32 UCHL5 UQCC2 VIM VPS52 ZBTB14 ZMYND12 ZSCAN32	7 interacting genes: EZR GABARAPL1 GABARAPL2 LHX8 SHANK3 TCAF1 TXN2
Entrez ID		25828	57147
HPRD ID		07161	07459
Ensembl ID		ENSG00000100348	ENSG00000000457
Uniprot IDs		Q99757	Q8IZE3
PDB IDs		1UVZ 1W4V 1W89
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Protein Binding Microtubule Organizing Center Organelle Organization Cytoskeleton Organization Cytoskeleton Membraneless Organelle Assembly Spindle Assembly Regulation Of Microtubule Cytoskeleton Organization Spindle Organization Synaptonemal Complex Microtubule Cytoskeleton Organization Cytoplasm Microtubule-based Process	Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding GABA Receptor Binding Organelle Assembly Beta-tubulin Binding Autophagosome Maturation Mitophagy Autophagosome Membrane Autophagy Of Mitochondrion ATPase Binding Autophagosome Terminal Web Assembly Positive Regulation Of Anion Channel Activity Autophagosome Organization Autophagosome Assembly Guanylate Kinase-associated Protein Clustering Protein Localization To Cell Cortex Intestinal D-glucose Absorption Positive Regulation Of Monoatomic Anion Transport Phospholipid Binding Positive Regulation Of Synapse Structural Plasticity Striatal Medium Spiny Neuron Differentiation Protein-containing Complex Disassembly Intestinal Hexose Absorption Synaptic Receptor Adaptor Activity Membrane To Membrane Docking Regulation Of Microvillus Length Macroautophagy Negative Regulation Of Cell Volume AMPA Glutamate Receptor Clustering NMDA Glutamate Receptor Clustering Vacuole Organization Cellular Response To Starvation Microvillus Assembly Postsynaptic Density Assembly Regulation Of Synapse Structural Plasticity Microvillus Organization Regulation Of Cellular Component Size Positive Regulation Of Early Endosome To Late Endosome Transport Positive Regulation Of Protein Localization To Early Endosome Establishment Of Centrosome Localization Microtubule Binding Regulation Of Cell Projection Size Negative Regulation Of P38MAPK Cascade Cortical Microtubule Organization Astral Microtubule Organization Response To Starvation Cellular Response To Nutrient Levels Tat Protein Binding Vocal Learning
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