TRIM8 and MAP3K7

  • Number of citations of the paper that reports this interaction (PMID 22084099)
  • 11
  • Data Source:
  • BioGRID (enzymatic study)

TRIM8

MAP3K7

Gene Name tripartite motif containing 8 mitogen-activated protein kinase kinase kinase 7
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 45 interactors: BRAP CBL CCNH ITSN1 MAP3K7 MKRN3 MSL2 OTUB2 PCGF5 RAD18 RC3H2 RCHY1 RNF111 RNF113A RNF138 RNF141 RNF181 RNF41 RNF7 SIAH1 SOCS1 TNFAIP3 TRAF5 TRIM15 TRIM2 TRIM21 TRIM24 TRIM25 TRIM39 TRIM43 TRIM47 TRIM9 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2L6 UBE2V1 UBE2W UHRF2 USP2 USP21 USP39 USP7 XIAP 60 interactors: BBS10 BCL10 CARD11 CHUK COPS5 EIF2AK2 EZH2 FOS GPR25 HGS HIPK2 IKBKAP IKBKB IL17RD IRAK1 MAP2K4 MAP2K6 MAP3K14 MAP3K3 MAP3K5 MAP4K1 MAP4K4 MAPK14 MAPK6 MAPK8 MAPK8IP1 MAVS NAIP NDUFS6 NOD2 NRIP1 PEBP1 PELI3 PINK1 PPM1B PPM1L PPP2R1A PPP5C PRKAA1 PRKAB1 RBX1 RELA RNF19A ROR2 SMAD3 SMAD6 SMAD7 STAT3 STRADB TAB1 TAB2 TGFBR1 TNFRSF11A TRAF3IP2 TRAF6 TRIM8 VRK2 XIAP ZNF593 ZNF746
Entrez ID 81603 6885
HPRD ID 06934 04011
Ensembl ID ENSG00000171206 ENSG00000135341
Uniprot IDs Q9BZR9 O43318
PDB IDs 2EVA 2YIY 4GS6 4L3P 4L52 4L53
Enriched GO Terms of Interacting Partners?
Tagcloud ?
aggressive  ccrcc  chemotherapeutic  cytotoxic  defective  deficit  define  dramatically  enhancer  impairing  impairs  inactivated  inactivation  link  mdm2  mechanistic  modulator  p53  rcc  re  regulators  renders  restoring  stabilizes  suppress  treating  tumours  way  wild 
abrogated  accounts  bcr  called  card  card11  carma1  existence  feedback  generating  ikappab  ikk  ikkbeta  implies  kappab  late  maguk  mathematical  modeling  module  nf  residue  scaffolding  serine  steep  switch  switchlike  tak1  threshold 
Tagcloud (Difference) ?
aggressive  ccrcc  chemotherapeutic  cytotoxic  defective  deficit  define  dramatically  enhancer  impairing  impairs  inactivated  inactivation  link  mdm2  mechanistic  modulator  p53  rcc  re  regulators  renders  restoring  stabilizes  suppress  treating  tumours  way  wild 
abrogated  accounts  bcr  called  card  card11  carma1  existence  feedback  generating  ikappab  ikk  ikkbeta  implies  kappab  late  maguk  mathematical  modeling  module  nf  residue  scaffolding  serine  steep  switch  switchlike  tak1  threshold 
Tagcloud (Intersection) ?