MAP3K7 and TGFBR1

  • Number of citations of the paper that reports this interaction (PMID 18758450)
  • 109
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vivo)

MAP3K7

TGFBR1

Gene Name mitogen-activated protein kinase kinase kinase 7 transforming growth factor, beta receptor 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 60 interactors: BBS10 BCL10 CARD11 CHUK COPS5 EIF2AK2 EZH2 FOS GPR25 HGS HIPK2 IKBKAP IKBKB IL17RD IRAK1 MAP2K4 MAP2K6 MAP3K14 MAP3K3 MAP3K5 MAP4K1 MAP4K4 MAPK14 MAPK6 MAPK8 MAPK8IP1 MAVS NAIP NDUFS6 NOD2 NRIP1 PEBP1 PELI3 PINK1 PPM1B PPM1L PPP2R1A PPP5C PRKAA1 PRKAB1 RBX1 RELA RNF19A ROR2 SMAD3 SMAD6 SMAD7 STAT3 STRADB TAB1 TAB2 TGFBR1 TNFRSF11A TRAF3IP2 TRAF6 TRIM8 VRK2 XIAP ZNF593 ZNF746 159 interactors: ACVR1 ACVRL1 AMHR2 ANAPC5 AP2B1 ARHGAP15 ARHGAP31 ARHGEF6 ARL4D ARL8B ASH2L AURKB BAMBI BMPR1B BMPR2 BTBD2 CAV1 CD44 CDC20 CDC42EP4 CDK14 CDK17 CDK4 CDK6 CDKL1 CHN1 CHN2 CHUK CLU CSNK1A1 CSNK2A2 CTNNB1 CUL5 DAB2 DAPK2 DCAF12 DCAF6 DUSP13 EIF2AK4 ENC1 ENG FANCL FBXL12 FBXO34 FKBP1A FNTA GNA13 GNB2 GNB3 IKBKB ITK KATNB1 KCNK18 KLHL1 KLHL35 LIMS1 MAP3K7 MYO3A MYOC NAT8 NEK6 NEK8 NKIRAS1 NRP1 NUAK2 NUP37 OSR1 OXSR1 PAK1 PARD6A PIK3R1 PIK3R2 PLEK PLEKHB1 PLEKHJ1 PLK4 PML POMK PPP2R2A PPP3CC PPP6C PREB PREX2 PRPF4 RAB13 RAB25 RAB33B RAB34 RAB38 RAB3B RAB6B RAN RAP2A RASD2 RASL12 RGS19 RHEBL1 RHOA RHOD RHOG RHOH RHOJ RHPN2 RNF130 RNF146 RNF5 RPAP3 RPS27A RRH RTKN SAMD8 SAT2 SKAP2 SKI SMAD1 SMAD2 SMAD3 SMAD4 SMAD6 SMAD7 SMURF2 SNTG1 SNX6 SOCS6 SQSTM1 STK35 STRAP STUB1 STX8 STYXL1 TGFB1 TGFB2 TGFB3 TGFBR2 TGFBRAP1 TNNT1 TRAF6 TRAP1 TSC22D1 TSSK1B TSSK4 TTC1 TTC27 TTPAL UBA52 UBB UBD UBE2E3 UBE2Z UBXN1 USP4 USP45 VEPH1 WDR13 WDR33 WDR61 XIAP ZAK ZFYVE9
Entrez ID 6885 7046
HPRD ID 04011 01822
Ensembl ID ENSG00000135341 ENSG00000106799
Uniprot IDs O43318 P36897 Q5T7S2
PDB IDs 2EVA 2YIY 4GS6 4L3P 4L52 4L53 1B6C 1IAS 1PY5 1RW8 1TBI 1VJY 2L5S 2PJY 2WOT 2WOU 2X7O 3FAA 3GXL 3HMM 3KCF 3KFD 3TZM
Enriched GO Terms of Interacting Partners?
Tagcloud ?
abrogated  accounts  bcr  called  card  card11  carma1  existence  feedback  generating  ikappab  ikk  ikkbeta  implies  kappab  late  maguk  mathematical  modeling  module  nf  residue  scaffolding  serine  steep  switch  switchlike  tak1  threshold 
calm3  cblb  ccna2  ccnd3  cdk6  cited1  dems  dok  elk3  fyn  git1  hck  lck  module  modules  nonmodule  p85beta  pdgfra  pib5pa  psd93  ptch2  sam68  sh3kbp1  shc  vav2  wilcoxon  yes  zfyve9 
Tagcloud (Difference) ?
abrogated  accounts  bcr  called  card  card11  carma1  existence  feedback  generating  ikappab  ikk  ikkbeta  implies  kappab  late  maguk  mathematical  modeling  nf  residue  scaffolding  serine  steep  switch  switchlike  tak1  threshold 
calm3  cblb  ccna2  ccnd3  cdk6  cited1  dems  dok  elk3  fyn  git1  hck  lck  modules  nonmodule  p85beta  pdgfra  pib5pa  psd93  ptch2  sam68  sh3kbp1  shc  vav2  wilcoxon  yes  zfyve9 
Tagcloud (Intersection) ?
module