CCDC130 and NINL

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CCDC130	NINL
Gene Name		coiled-coil domain containing 130	ninein-like
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component	Microtubule Organizing Center Cytosol Microtubule
	Molecular Function	Protein Binding	Calcium Ion Binding
	Biological Process	Response To Virus	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization
Pathways			Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: EEF1A1 JUP NINL TRAF2 ZBTB16 ZNF165 ZNF24 ZNF572	45 interactors: AKAP17A APEX2 CCDC130 CCDC146 CCDC33 CCHCR1 CLEC1B DCTN5 EWSR1 EZH2 FAM107A FAM161A GCC1 GPKOW HAUS1 JUNB KANSL1 KAT5 KAT7 L3MBTL4 LRSAM1 LZTS2 MAD1L1 MBIP MCM10 PLK1 RBM41 RCOR3 RGS2 RIBC2 SH2D4A SH3BP5L SPERT SYT17 TCEANC TCEB3 TNNT1 TSPYL4 UTP14A ZFC3H1 ZFHX3 ZNF250 ZNF417 ZNF426 ZNF646
Entrez ID		81576	22981
HPRD ID		11304	11120
Ensembl ID		ENSG00000104957	ENSG00000101004
Uniprot IDs		P13994	Q9Y2I6
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Protein Heterooligomerization Endothelial Cell-cell Adhesion Desmosome Assembly Positive Regulation Of NK T Cell Differentiation Cellular Response To Indole-3-methanol RNA Metabolic Process Regulation Of Metabolic Process Male Germ-line Stem Cell Asymmetric Division Positive Regulation Of T Cell Activation Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Homotypic Cell-cell Adhesion Negative Regulation Of Glial Cell Apoptotic Process Gene Expression Bundle Of His Cell To Purkinje Myocyte Communication Desmosome Organization Positive Regulation Of Cell-cell Adhesion Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Protein Homodimerization Activity Cytoskeletal Anchoring At Plasma Membrane Cellular Response To Nitric Oxide Regulation Of T Cell Activation Positive Regulation Of Cell Activation Regulation Of Immunoglobulin Secretion Response To Nitric Oxide Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Protein Homotrimerization Positive Regulation Of T Cell Cytokine Production Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Adhesion Regulation Of Cell Fate Specification Regulation Of Protein Homodimerization Activity Ventricular Cardiac Muscle Cell Action Potential Regulation Of Lymphocyte Activation Cellular Response To Reactive Nitrogen Species Regulation Of Heart Rate By Cardiac Conduction Protein Oligomerization Nucleobase-containing Compound Metabolic Process Cellular Response To Epidermal Growth Factor Stimulus Regulation Of T Cell Cytokine Production Activation Of NF-kappaB-inducing Kinase Activity	RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Histone Acetylation Internal Peptidyl-lysine Acetylation Gene Expression Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Peptidyl-lysine Modification Protein Acetylation Cellular Nitrogen Compound Metabolic Process Chromatin Organization Protein Localization To Chromatin Chromosome Organization Cell Cycle Histone H4-K5 Acetylation Histone H4-K8 Acetylation Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Chromatin Modification Histone Modification Regulation Of Transcription, DNA-templated Negative Regulation Of Muscle Contraction Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of RNA Metabolic Process Organelle Organization Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Protein Localization To Chromosome Cell Cycle Process Mitotic Spindle Checkpoint Negative Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Chromosome Segregation Mitotic Nuclear Division Inactivation Of MAPK Activity Involved In Osmosensory Signaling Pathway Ubiquitin-dependent Endocytosis Regulation Of Metaphase Plate Congression Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Spindle Checkpoint Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Muscle Cell Differentiation Regulation Of Nitrogen Compound Metabolic Process
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