YJU2B and CLP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		YJU2B	CLP1
Description		YJU2 splicing factor homolog B	cleavage factor polyribonucleotide kinase subunit 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus U2-type Spliceosomal Complex Post-mRNA Release Spliceosomal Complex	TRNA-intron Endonuclease Complex Nucleus Nucleoplasm Cytosol MRNA Cleavage Factor Complex
	Molecular Function	Protein Binding	Nucleotide Binding Protein Binding ATP Binding Kinase Activity Transferase Activity ATP-dependent Polydeoxyribonucleotide 5'-hydroxyl-kinase Activity Polynucleotide 5'-hydroxyl-kinase Activity ATP-dependent Polynucleotide 5'-hydroxyl-kinase Activity ATP-dependent Polyribonucleotide 5'-hydroxyl-kinase Activity
	Biological Process	MRNA Splicing, Via Spliceosome RNA Splicing Response To Virus	TRNA Splicing, Via Endonucleolytic Cleavage And Ligation RNA Processing MRNA Processing TRNA Processing Cerebellar Cortex Development MRNA 3'-end Processing RISC Complex Assembly Global Gene Silencing By MRNA Cleavage
Pathways			tRNA processing in the nucleus mRNA 3'-end processing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Neuroticism ( 29255261) Schizophrenia ( 25056061 29483656)
Interacting Genes		27 interacting genes: CLP1 EEF1A1 EFHC1 HSF2BP JUP NINL OGT SMARCD1 TRAF2 TRIM55 TRIM63 TSSK3 ZBTB16 ZFP3 ZNF165 ZNF17 ZNF24 ZNF250 ZNF3 ZNF329 ZNF35 ZNF572 ZNF629 ZNF774 ZNF79 ZNF835 ZSCAN23	16 interacting genes: APP CEP164 CPSF3 CREB3 DAGLB FGF16 FTO HCFC1 MEOX2 MESD NUDT21 PCMT1 PRR3 PSMB5 SNF8 YJU2B
Entrez ID		81576	10978
HPRD ID		11304	16382
Ensembl ID		ENSG00000104957	ENSG00000172409
Uniprot IDs		B7Z1U2 P13994	Q92989
PDB IDs			8HMY 8HMZ
Enriched GO Terms of Interacting Partners?		Zinc Ion Binding Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Metal Ion Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process DNA Binding Regulation Of Primary Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Nucleus DNA-binding Transcription Factor Activity, RNA Polymerase II-specific	Release From Viral Latency Co-transcriptional MRNA 3'-end Processing, Cleavage And Polyadenylation Pathway Co-transcriptional RNA 3'-end Processing, Cleavage And Polyadenylation Pathway MRNA Cleavage And Polyadenylation Specificity Factor Complex Positive Regulation Of Monocyte Chemotaxis Amyloid-beta Complex Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Regulation Of Chemotaxis Low-density Lipoprotein Particle Receptor Binding Positive Regulation Of Chemotaxis Amylin Binding Positive Regulation Of Toll Signaling Pathway Chromatin Binding Regulation Of Monocyte Chemotaxis Positive Regulation Of Deacetylase Activity MRNA 3'-end Processing Positive Regulation Of Pro-B Cell Differentiation RNA Repair TRNA Demethylase Activity
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