DIXDC1

Description		DIX domain containing 1
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GO Annotations	Cellular Component	Stress Fiber Cytoplasm Cytosol Cytoskeleton Focal Adhesion Anchoring Junction Postsynapse Glutamatergic Synapse
	Molecular Function	Actin Binding Protein Binding Protein Domain Specific Binding Gamma-tubulin Binding
	Biological Process	Wnt Signaling Pathway Cerebral Cortex Cell Migration Cerebral Cortex Radially Oriented Cell Migration Cell Proliferation In Forebrain Forebrain Ventricular Zone Progenitor Cell Division Positive Regulation Of Wnt Signaling Pathway Regulation Of Actin Cytoskeleton Organization Negative Regulation Of Neuron Differentiation Canonical Wnt Signaling Pathway Regulation Of Microtubule Cytoskeleton Organization Modification Of Postsynaptic Actin Cytoskeleton
Pathways
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Smoking initiation ( 33082346) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		8 interacting genes: APP ATXN1 AXIN1 CDC5L MAP3K4 NDEL1 ULK2 ZDHHC17
Entrez ID		85458
HPRD ID		16804
Ensembl ID		ENSG00000150764
Uniprot IDs		Q155Q3
PDB IDs		3PZ7
Enriched GO Terms of Interacting Partners?		Axonogenesis Cell Projection Morphogenesis Neuron Projection Morphogenesis Collateral Sprouting Developmental Cell Growth Developmental Growth Involved In Morphogenesis Identical Protein Binding Protein Serine/threonine Kinase Binding Regulation Of MAPK Cascade Anatomical Structure Morphogenesis Amyloid-beta Complex Growth Cone Lamellipodium Response To Light Stimulus Visual Behavior Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Visual Learning Cytoplasmic Vesicle Signal Transduction Beta-catenin Destruction Complex Assembly Somatic Sensory System Development Perforant Pathway To Dendrate Granule Cell Synapse Developmental Growth Adult Locomotory Behavior Axo-dendritic Transport Acetylcholine Receptor Activator Activity Associative Learning Positive Regulation Of MAPK Cascade Positive Regulation Of JNK Cascade Lipoprotein Particle Cell Projection Organization Positive Regulation Of Protein Import Response To Radiation Male Germ-line Sex Determination Axial Mesoderm Formation Neuron Projection Extension Postsynaptic Golgi Apparatus Regulation Of Modification Of Synapse Structure, Modulating Synaptic Transmission Neurofilament Cytoskeleton PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Intracellular Transport Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Positive Regulation Of Intracellular Signal Transduction Memory Developmental Process
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