SNAPC5 and ARHGEF38

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SNAPC5	ARHGEF38
Description		small nuclear RNA activating complex polypeptide 5	Rho guanine nucleotide exchange factor 38
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Nuclear Body	Cytoplasm
	Molecular Function	RNA Polymerase III General Transcription Initiation Factor Activity Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity	Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Transcription By RNA Polymerase II Transcription Initiation At RNA Polymerase III Promoter SnRNA Transcription By RNA Polymerase II SnRNA Transcription By RNA Polymerase III
Pathways		RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter	NRAGE signals death through JNK G alpha (12/13) signalling events
Drugs
Diseases
GWAS			Chronic obstructive pulmonary disease ( 28166215) High density lipoprotein cholesterol levels ( 30498476) Post bronchodilator FEV1/FVC ratio ( 26634245) Regular attendance at a religious group ( 29970889) Serum bilirubin levels in metabolic syndrome ( 30621171) Weight ( 28548082)
Interacting Genes		43 interacting genes: AMOT ARHGEF38 BATF BFSP2 BLOC1S1 BRCC3 CBY2 CCDC196 CDCA8 CREB5 CREBBP CYTH1 CYTH4 DDIT3 EMILIN1 FAM9C GALR1 GORAB GRIPAP1 HMG20B ITGB3BP JUN LMO2 MBD3L1 MCRS1 MYF5 NDEL1 NMI NOL4 NUDT10 NUP62 POLR2J RNF4 S100Z SNAPC1 SNAPC4 STMN4 TRAPPC2 TRAPPC2B TXLNB ZNF177 ZNF559-ZNF177 ZNRD2	1 interacting genes: SNAPC5
Entrez ID		10302	54848
HPRD ID		16183	08613
Ensembl ID		ENSG00000174446	ENSG00000236699
Uniprot IDs		O75971	Q9NXL2
PDB IDs		7ZWC 7ZWD 7ZX7 7ZX8 7ZXE
Enriched GO Terms of Interacting Partners?		SnRNA-activating Protein Complex Peptidyl-lysine Acetylation Protein Binding Integrated Stress Response Signaling RNA Polymerase II Transcription Regulator Complex CAMP Response Element Binding TRAPPII Protein Complex TRAPPIII Protein Complex SnRNA Transcription By RNA Polymerase II SnRNA Transcription By RNA Polymerase III RNA Polymerase III General Transcription Initiation Factor Activity Positive Regulation Of Mitotic Cytokinesis Centrosome Separation Mitotic Centrosome Separation SnRNA Transcription Regulation Of Mitotic Cytokinesis	Transcription Initiation At RNA Polymerase III Promoter SnRNA Transcription By RNA Polymerase II SnRNA Transcription SnRNA Transcription By RNA Polymerase III RNA Polymerase III General Transcription Initiation Factor Activity Transcription By RNA Polymerase III RNA Polymerase II General Transcription Initiation Factor Activity SnRNA Metabolic Process DNA-templated Transcription Initiation
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