SNAPC5 and SNAPC4

Number of citations of the paper that reports this interaction (PMID 11056176)
14

Data Source:
HPRD (in vitro, in vivo)

		SNAPC5	SNAPC4
Gene Name		small nuclear RNA activating complex, polypeptide 5, 19kDa	small nuclear RNA activating complex, polypeptide 4, 190kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus	Nucleus Nucleoplasm SnRNA-activating Protein Complex
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity	DNA Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity
	Biological Process	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase III Promoter Transcription Initiation From RNA Polymerase III Promoter Gene Expression	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase III Promoter SnRNA Transcription Gene Expression SnRNA Transcription From RNA Polymerase II Promoter SnRNA Transcription From RNA Polymerase III Promoter
Pathways		RNA Polymerase III Transcription RNA Polymerase III Transcription Initiation RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase III Abortive And Retractive Initiation	RNA Polymerase III Transcription RNA Polymerase III Transcription Initiation RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase III Abortive And Retractive Initiation
Drugs
Diseases
GWAS			Crohn's disease ( 22936669 21102463) Ulcerative colitis ( 21297633)
Protein-Protein Interactions		14 interactors: AMOT BATF BRCC3 CYTH4 DDIT3 JUN NDEL1 NMI NOL4 NUDT10 NUP62 SNAPC1 SNAPC4 SSSCA1	8 interactors: BRF2 HNRNPD MAPK6 POU2F1 SNAPC1 SNAPC2 SNAPC5 TBP
Entrez ID		10302	6621
HPRD ID		16183	04146
Ensembl ID		ENSG00000174446	ENSG00000165684
Uniprot IDs		O75971	Q5SXM2
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Small GTPase Mediated Signal Transduction Transcription, DNA-templated Regulation Of Catalytic Activity RNA Biosynthetic Process Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Cell Cycle Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nuclear Envelope Disassembly Cellular Nitrogen Compound Metabolic Process Transcription From RNA Polymerase III Promoter Regulation Of Ras Protein Signal Transduction Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Cell Cycle Positive Regulation Of Neuron Apoptotic Process Nitrogen Compound Metabolic Process Nuclear Envelope Organization Negative Regulation Of Determination Of Dorsal Identity Cellular Response To Potassium Ion Starvation Regulation Of GTPase Activity RNA Metabolic Process Positive Regulation Of Neuron Death Transcription From RNA Polymerase II Promoter Gene Expression Leading Edge Cell Differentiation ADP Catabolic Process Establishment Of Cell Polarity Involved In Ameboidal Cell Migration Regulation Of Transcription Involved In Anterior/posterior Axis Specification Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Intracellular Signal Transduction Histone H2A K63-linked Deubiquitination IDP Catabolic Process Establishment Of Cell Polarity Positive Regulation Of Hydrolase Activity Myeloid Leukocyte Differentiation Nucleus Organization Regulation Of Signal Transduction T-helper 2 Cell Differentiation Intracellular Signal Transduction Regulation Of Cell Size Blood Vessel Development T-helper 17 Cell Lineage Commitment SnRNA Transcription From RNA Polymerase III Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Vasculature Development	Transcription From RNA Polymerase III Promoter Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process DNA-templated Transcription, Initiation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of MRNA Stability Regulation Of RNA Stability Nitrogen Compound Metabolic Process Cellular Metabolic Process RNA Catabolic Process Regulation Of Metabolic Process Circadian Regulation Of Translation Olfactory Placode Formation SnRNA Transcription Lens Induction In Camera-type Eye Regulation Of Cellular Process Transcription Initiation From RNA Polymerase III Promoter Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Chromatin Silencing At RDNA Positive Regulation Of Cellular Metabolic Process Positive Regulation Of MRNA Catabolic Process Nose Development Positive Regulation Of Transcription, DNA-templated Definitive Hemopoiesis Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter Aromatic Compound Catabolic Process Posttranscriptional Regulation Of Gene Expression Somatic Stem Cell Division Transcription Initiation From RNA Polymerase I Promoter Lens Morphogenesis In Camera-type Eye Positive Regulation Of Macromolecule Biosynthetic Process Transcription From RNA Polymerase I Promoter Negative Regulation Of Stem Cell Differentiation Positive Regulation Of Gene Expression
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