YEATS4 and PFDN1

Number of citations of the paper that reports this interaction (PubMedID 11521196)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		YEATS4	PFDN1
Description		YEATS domain containing 4	prefoldin subunit 1
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GO Annotations	Cellular Component	Nucleosome Nucleus Nucleoplasm Nuclear Matrix Nuclear Membrane NuA4 Histone Acetyltransferase Complex	Cytoplasm Prefoldin Complex Protein-containing Complex
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Histone Binding Histone H3K18ac Reader Activity Histone H3K27ac Reader Activity	Amyloid-beta Binding Protein Binding Protein Folding Chaperone Unfolded Protein Binding
	Biological Process	Mitotic Cell Cycle Chromatin Organization Chromatin Remodeling Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Cytoskeleton Organization Regulation Of Apoptotic Process Positive Regulation Of DNA-templated Transcription Regulation Of Cell Cycle Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Double-strand Break Repair	Protein Folding Negative Regulation Of Amyloid Fibril Formation
Pathways		HATs acetylate histones Activation of the TFAP2 (AP-2) family of transcription factors	Prefoldin mediated transfer of substrate to CCT/TriC
Drugs
Diseases
GWAS		Complete remission in asthma ( 29786918) Height ( 18391951 31562340) Metabolite levels ( 23823483) Response to antidepressants (symptom remission) ( 29160301) Response to diuretic therapy ( 18591461) Response to SSRI in MDD or conscientiousness ( 29559929) Thyroid stimulating hormone levels ( 32769997)	Alzheimer's disease ( 28183528) Alzheimer's disease in APOE e4- carriers ( 25778476) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Reaction time ( 29844566)
Interacting Genes		16 interacting genes: CEP162 FRMD4A GTF2F2 H3C1 MLLT10 MRGBP MYCN NUMA1 PFDN1 RNF8 SMARCB1 TACC1 TACC2 TFAP2B TPM1 TRIM54	55 interacting genes: ACTA1 ACTB ALB BRK1 CCDC85A CEBPA CEP126 CHGA DCTN1 DEFA1 DMAP1 EDRF1 EIF3C EIF4A2 EOMES ESS2 EXT2 EZH2 FAM20C GET3 GIT1 GPRASP1 HAP1 HIP1 HMGXB3 HOXD8 IFT140 IMMT INPP5K JADE1 KIAA0408 LRIF1 MED31 NDC80 NR2F1 PDE4DIP PDHB PFDN2 PLXNB2 PRKD2 PSME1 PTN RMI1 RPLP1 RPS28 SEC31A SKP2 SNX5 SPTBN4 SUMO3 SYNDIG1 TERT TTC38 YEATS4 ZNF235
Entrez ID		8089	5201
HPRD ID		03666	05357
Ensembl ID		ENSG00000127337	ENSG00000113068
Uniprot IDs		F8W0J4 O95619	O60925
PDB IDs		5R68 5R69 5VNA 5VNB 5XTZ 5Y8V 7EIF 7JFY 8DKB 8I60 8IIY 8IIZ 8IJ0 8X15 8X19 8X1C	6NR8 6NR9 6NRB 6NRC 6NRD 7WU7
Enriched GO Terms of Interacting Partners?		Nucleoplasm RNA Polymerase II, Holoenzyme Positive Regulation Of RNA Metabolic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Chromatin Organization Epigenetic Regulation Of Gene Expression Cortical Microtubule Spindle Organization Anastral Spindle Assembly Cytoplasmic Microtubule Bundle Positive Regulation Of Protein Localization To Spindle Pole Body Protein-containing Complex Cytoskeleton Microtubule Cytoskeleton Organization Involved In Mitosis Regulation Of Supramolecular Fiber Organization Positive Regulation Of Mitotic Spindle Elongation Positive Regulation Of Double-strand Break Repair Regulation Of Double-strand Break Repair Positive Regulation Of DNA Repair Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Nuclear Receptor Binding Nucleus Localization Nuclear Migration Positive Regulation Of Heart Rate By Epinephrine Positive Regulation Of Double-strand Break Repair Via Homologous Recombination H4/H2A Histone Acetyltransferase Complex Regulation Of DNA Repair Regulation Of Epidermal Cell Differentiation Transcription Factor TFIIF Complex Regulation Of Epidermis Development Establishment Of Organelle Localization Lateral Cell Cortex Positive Regulation Of DNA Metabolic Process Nucleus Chromatin Remodeling Cell Cortex Region Centrosome Positive Regulation Of Glucose Mediated Signaling Pathway Germ Cell Nucleus Cerebral Cortex Development Metanephric Nephron Development Positive Regulation Of DNA Recombination Regulation Of Double-strand Break Repair Via Homologous Recombination Mitotic Spindle Astral Microtubule Microtubule Regulation Of Glucose Mediated Signaling Pathway Mitotic Spindle Organization Distal Tubule Development	Positive Regulation Of Microtubule Nucleation Structural Constituent Of Cytoskeleton Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Microtubule Nucleation Nuclear Matrix Positive Regulation Of DNA Recombination NuA4 Histone Acetyltransferase Complex Regulation Of Cell Cycle Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Microtubule Polymerization Positive Regulation Of Double-strand Break Repair Intracellular Protein Localization Regulation Of Cell Cycle G1/S Phase Transition Positive Regulation Of Cytoskeleton Organization Regulation Of Supramolecular Fiber Organization Glutamate Receptor Binding Regulation Of Cellular Component Organization
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