YEATS4 and FRMD4A

Number of citations of the paper that reports this interaction (PMID 22068108)
1

Data Source:
BioGRID (two hybrid)

		YEATS4	FRMD4A
Gene Name		YEATS domain containing 4	FERM domain containing 4A
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Nuclear Matrix NuA4 Histone Acetyltransferase Complex	Cytoplasm Cytoskeleton Tight Junction
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Structural Constituent Of Cytoskeleton Protein Binding Protein C-terminus Binding	Protein Binding, Bridging
	Biological Process	Chromatin Organization Transcription, DNA-templated Mitotic Nuclear Division Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation Positive Regulation Of Transcription, DNA-templated	Establishment Of Epithelial Cell Polarity
Pathways		Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS		Height ( 18391951) Response to diuretic therapy ( 18591461)	Alzheimer's disease ( 22430674) RR interval (heart rate) ( 20031603)
Protein-Protein Interactions		14 interactors: CEP162 FRMD4A KDM1A MLLT10 MRGBP MYC MYCN NUMA1 PFDN1 RNF8 SMARCB1 TACC1 TACC2 TFAP2B	2 interactors: TRAF3IP1 YEATS4
Entrez ID		8089	55691
HPRD ID		03666	13553
Ensembl ID		ENSG00000127337	ENSG00000151474
Uniprot IDs		F8W0J4 O95619	Q9P2Q2
PDB IDs
Enriched GO Terms of Interacting Partners?		Organelle Organization Cell Cycle Anatomical Structure Development Positive Regulation Of Stem Cell Proliferation System Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Modification Developmental Process Regulation Of Transcription From RNA Polymerase II Promoter Interkinetic Nuclear Migration Chromatin Organization Regulation Of Stem Cell Proliferation Multicellular Organismal Development Regulation Of Response To DNA Damage Stimulus Positive Regulation Of Transcription, DNA-templated Organ Development Forebrain Development Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Nervous System Development Chromatin Remodeling Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Chromosome Organization Cell Cycle Process Regulation Of RNA Metabolic Process Cell Differentiation Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Mesenchymal Cell Proliferation Nucleus Localization Cell Proliferation In Forebrain Regulation Of Mesenchymal Cell Proliferation Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Telencephalon Development Tube Development Positive Regulation Of Metanephric Cap Mesenchymal Cell Proliferation Cellular Creatinine Homeostasis Cellular Urea Homeostasis Cellular Ammonia Homeostasis Regulation Of Primitive Erythrocyte Differentiation Positive Regulation Of Response To DNA Damage Stimulus ATP-dependent Chromatin Remodeling Brain Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Head Development Positive Regulation Of Cell Proliferation Regulation Of Cell Proliferation	Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Negative Regulation Of Interferon-beta Production Histone H2A Acetylation
Tagcloud ?		12q13 abrogated amplified attenuation bronchial candidate cisplastin cleavage colony contributing conversely copy define helped identifying impairing implicating inducing integrative matched nsclc oncogene oncogenes overexpressed p21waf1 parp reveal rnai senescence	amyloidogenic beta40 beta42 bin1 biopsies braak categorized cerebrospinal clu dichotomized displays exons grouped hydrocephalus idiopathic inferior mechanistic ms4a6a neurofibrillary pathology postmortem relation responding secretase shunt splicing trait trem2 vi
Tagcloud (Difference) ?		12q13 abrogated amplified attenuation bronchial candidate cisplastin cleavage colony contributing conversely copy define helped identifying impairing implicating inducing integrative matched nsclc oncogene oncogenes overexpressed p21waf1 parp reveal rnai senescence	amyloidogenic beta40 beta42 bin1 biopsies braak categorized cerebrospinal clu dichotomized displays exons grouped hydrocephalus idiopathic inferior mechanistic ms4a6a neurofibrillary pathology postmortem relation responding secretase shunt splicing trait trem2 vi
Tagcloud (Intersection) ?