YEATS4 and CEP162

Number of citations of the paper that reports this interaction (PMID 11521196)
11

Data Source:
BioGRID (two hybrid)

		YEATS4	CEP162
Gene Name		YEATS domain containing 4	centrosomal protein 162kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Nuclear Matrix NuA4 Histone Acetyltransferase Complex	Nucleoplasm Cytoplasm Centrosome Centriole Spindle Cytosol Axonemal Microtubule
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Structural Constituent Of Cytoskeleton Protein Binding Protein C-terminus Binding	Protein Binding
	Biological Process	Chromatin Organization Transcription, DNA-templated Mitotic Nuclear Division Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation Positive Regulation Of Transcription, DNA-templated	Organelle Organization Cilium Assembly
Pathways		Chromatin modifying enzymes Chromatin organization HATs acetylate histones	Organelle biogenesis and maintenance Assembly of the primary cilium Anchoring of the basal body to the plasma membrane
Drugs
Diseases
GWAS		Height ( 18391951) Response to diuretic therapy ( 18591461)
Protein-Protein Interactions		14 interactors: CEP162 FRMD4A KDM1A MLLT10 MRGBP MYC MYCN NUMA1 PFDN1 RNF8 SMARCB1 TACC1 TACC2 TFAP2B	6 interactors: CPNE4 KDM1A PRMT1 PRMT8 SPP1 YEATS4
Entrez ID		8089	22832
HPRD ID		03666	10796
Ensembl ID		ENSG00000127337	ENSG00000135315
Uniprot IDs		F8W0J4 O95619	Q5TB80
PDB IDs
Enriched GO Terms of Interacting Partners?		Organelle Organization Cell Cycle Anatomical Structure Development Positive Regulation Of Stem Cell Proliferation System Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Modification Developmental Process Regulation Of Transcription From RNA Polymerase II Promoter Interkinetic Nuclear Migration Chromatin Organization Regulation Of Stem Cell Proliferation Multicellular Organismal Development Regulation Of Response To DNA Damage Stimulus Positive Regulation Of Transcription, DNA-templated Organ Development Forebrain Development Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Nervous System Development Chromatin Remodeling Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Chromosome Organization Cell Cycle Process Regulation Of RNA Metabolic Process Cell Differentiation Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Mesenchymal Cell Proliferation Nucleus Localization Cell Proliferation In Forebrain Regulation Of Mesenchymal Cell Proliferation Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Telencephalon Development Tube Development Positive Regulation Of Metanephric Cap Mesenchymal Cell Proliferation Cellular Creatinine Homeostasis Cellular Urea Homeostasis Cellular Ammonia Homeostasis Regulation Of Primitive Erythrocyte Differentiation Positive Regulation Of Response To DNA Damage Stimulus ATP-dependent Chromatin Remodeling Brain Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Head Development Positive Regulation Of Cell Proliferation Regulation Of Cell Proliferation	Histone Modification Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Chromatin Modification Peptidyl-arginine N-methylation Histone H4-R3 Methylation Chromatin Organization Histone Arginine Methylation Peptidyl-arginine Methylation Regulation Of Megakaryocyte Differentiation Regulation Of Hematopoietic Progenitor Cell Differentiation Chromosome Organization Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Regulation Of Primitive Erythrocyte Differentiation Histone Methylation Regulation Of Protein Binding Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Protein Methylation Regulation Of Myeloid Cell Differentiation Peptidyl-amino Acid Modification Negative Regulation Of Megakaryocyte Differentiation Regulation Of Binding Negative Regulation Of Collateral Sprouting Organelle Organization Cellular Protein Modification Process Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Negative Regulation Of Axon Regeneration Histone H3-K4 Demethylation Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Positive Regulation Of Megakaryocyte Differentiation Positive Regulation Of Hormone Biosynthetic Process Negative Regulation Of Histone H3-K9 Methylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Cell Differentiation Methylation Histone H2A Acetylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Positive Regulation Of Bone Resorption Granulocyte Differentiation Regulation Of Axon Regeneration Negative Regulation Of Histone Methylation In Utero Embryonic Development Positive Regulation Of Erythrocyte Differentiation Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Cellular Protein Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of Histone H3-K4 Methylation
Tagcloud ?		12q13 abrogated amplified attenuation bronchial candidate cisplastin cleavage colony contributing conversely copy define helped identifying impairing implicating inducing integrative matched nsclc oncogene oncogenes overexpressed p21waf1 parp reveal rnai senescence
Tagcloud (Difference) ?		12q13 abrogated amplified attenuation bronchial candidate cisplastin cleavage colony contributing conversely copy define helped identifying impairing implicating inducing integrative matched nsclc oncogene oncogenes overexpressed p21waf1 parp reveal rnai senescence
Tagcloud (Intersection) ?