YEATS4 and CEP162

Number of citations of the paper that reports this interaction (PubMedID 11521196)
0

Data Source:
BioGRID (two hybrid)

		YEATS4	CEP162
Description		YEATS domain containing 4	centrosomal protein 162
Image			No pdb structure
GO Annotations	Cellular Component	Nucleosome Nucleus Nucleoplasm Nuclear Matrix Nuclear Membrane NuA4 Histone Acetyltransferase Complex	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Centrosome Centriole Spindle Cytosol Cytoskeleton Microtubule Axonemal Microtubule Centriolar Satellite Ciliary Basal Body
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Histone Binding Histone H3K18ac Reader Activity Histone H3K27ac Reader Activity	Protein Binding
	Biological Process	Mitotic Cell Cycle Chromatin Organization Chromatin Remodeling Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Cytoskeleton Organization Regulation Of Apoptotic Process Positive Regulation Of DNA-templated Transcription Regulation Of Cell Cycle Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Double-strand Break Repair	Cell Projection Organization Cilium Assembly
Pathways		HATs acetylate histones Activation of the TFAP2 (AP-2) family of transcription factors	Anchoring of the basal body to the plasma membrane
Drugs
Diseases
GWAS		Complete remission in asthma ( 29786918) Height ( 18391951 31562340) Metabolite levels ( 23823483) Response to antidepressants (symptom remission) ( 29160301) Response to diuretic therapy ( 18591461) Response to SSRI in MDD or conscientiousness ( 29559929) Thyroid stimulating hormone levels ( 32769997)	Diabetic retinopathy in type 2 diabetes ( 25364816)
Interacting Genes		16 interacting genes: CEP162 FRMD4A GTF2F2 H3C1 MLLT10 MRGBP MYCN NUMA1 PFDN1 RNF8 SMARCB1 TACC1 TACC2 TFAP2B TPM1 TRIM54	7 interacting genes: CPNE4 KDM1A MTDH PRMT1 PRMT8 SPP1 YEATS4
Entrez ID		8089	22832
HPRD ID		03666	10796
Ensembl ID		ENSG00000127337	ENSG00000135315
Uniprot IDs		F8W0J4 O95619	Q5TB80
PDB IDs		5R68 5R69 5VNA 5VNB 5XTZ 5Y8V 7EIF 7JFY 8DKB 8I60 8IIY 8IIZ 8IJ0 8X15 8X19 8X1C
Enriched GO Terms of Interacting Partners?		Nucleoplasm RNA Polymerase II, Holoenzyme Positive Regulation Of RNA Metabolic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Chromatin Organization Epigenetic Regulation Of Gene Expression Cortical Microtubule Spindle Organization Anastral Spindle Assembly Cytoplasmic Microtubule Bundle Positive Regulation Of Protein Localization To Spindle Pole Body Protein-containing Complex Cytoskeleton Microtubule Cytoskeleton Organization Involved In Mitosis Regulation Of Supramolecular Fiber Organization Positive Regulation Of Mitotic Spindle Elongation Positive Regulation Of Double-strand Break Repair Regulation Of Double-strand Break Repair Positive Regulation Of DNA Repair Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Nuclear Receptor Binding Nucleus Localization Nuclear Migration Positive Regulation Of Heart Rate By Epinephrine Positive Regulation Of Double-strand Break Repair Via Homologous Recombination H4/H2A Histone Acetyltransferase Complex Regulation Of DNA Repair Regulation Of Epidermal Cell Differentiation Transcription Factor TFIIF Complex Regulation Of Epidermis Development Establishment Of Organelle Localization Lateral Cell Cortex Positive Regulation Of DNA Metabolic Process Nucleus Chromatin Remodeling Cell Cortex Region Centrosome Positive Regulation Of Glucose Mediated Signaling Pathway Germ Cell Nucleus Cerebral Cortex Development Metanephric Nephron Development Positive Regulation Of DNA Recombination Regulation Of Double-strand Break Repair Via Homologous Recombination Mitotic Spindle Astral Microtubule Microtubule Regulation Of Glucose Mediated Signaling Pathway Mitotic Spindle Organization Distal Tubule Development	Protein-arginine Omega-N Monomethyltransferase Activity Peptidyl-arginine Methylation Protein-arginine Omega-N Asymmetric Methyltransferase Activity Histone H4 Methyltransferase Activity Regulation Of Double-strand Break Repair Via Homologous Recombination Protein-arginine N-methyltransferase Activity Regulation Of DNA Recombination Regulation Of Double-strand Break Repair Regulation Of Cellular Response To Stress S-adenosyl-L-methionine Binding Chromatin Remodeling Histone Methyltransferase Activity Protein Methylation Regulation Of DNA Repair Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Chromatin Organization Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Enzyme Binding Positive Regulation Of DNA Recombination Regulation Of RNA Metabolic Process GATOR1 Complex Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Double-strand Break Repair Regulation Of DNA Metabolic Process Positive Regulation Of Estradiol Secretion Histone H3K18ac Reader Activity Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Macromolecule Methylation Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Estradiol Secretion Histone H3K27ac Reader Activity Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling Positive Regulation Of DNA Repair Regulation Of Multicellular Organismal Development Positive Regulation Of Biosynthetic Process Response To Nutrient N-methyltransferase Activity Protein Demethylase Activity Histone H4R3 Methyltransferase Activity Methyltransferase Activity Positive Regulation Of Hemoglobin Biosynthetic Process Androgen Catabolic Process MRF Binding Regulation Of Hemoglobin Biosynthetic Process Mitogen-activated Protein Kinase P38 Binding Response To Methionine
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