YEATS4 and TACC1

Number of citations of the paper that reports this interaction (PMID 11903063)
12

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo, in vitro, two hybrid)

		YEATS4	TACC1
Gene Name		YEATS domain containing 4	transforming, acidic coiled-coil containing protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Nuclear Matrix NuA4 Histone Acetyltransferase Complex	Nucleus Cytoplasm Microtubule Organizing Center Microtubule Cytoskeleton Intermediate Filament Cytoskeleton
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Structural Constituent Of Cytoskeleton Protein Binding Protein C-terminus Binding	Protein Binding Protein Domain Specific Binding
	Biological Process	Chromatin Organization Transcription, DNA-templated Mitotic Nuclear Division Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation Positive Regulation Of Transcription, DNA-templated	Microtubule Cytoskeleton Organization Cell Cycle Cell Proliferation Cerebral Cortex Development Neurogenesis Interkinetic Nuclear Migration Regulation Of Microtubule-based Process Cell Division
Pathways		Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS		Height ( 18391951) Response to diuretic therapy ( 18591461)
Protein-Protein Interactions		14 interactors: CEP162 FRMD4A KDM1A MLLT10 MRGBP MYC MYCN NUMA1 PFDN1 RNF8 SMARCB1 TACC1 TACC2 TFAP2B	16 interactors: AURKA AURKB BTRC CKAP5 HTT ITSN2 KAT2A KDM1A LSM7 MEMO1 PRKRIR SH2D4A SNRPG STX5 TDRD7 YEATS4
Entrez ID		8089	6867
HPRD ID		03666	10391
Ensembl ID		ENSG00000127337	ENSG00000147526
Uniprot IDs		F8W0J4 O95619	G8JLK4 O75410 Q5HYH0
PDB IDs
Enriched GO Terms of Interacting Partners?		Organelle Organization Cell Cycle Anatomical Structure Development Positive Regulation Of Stem Cell Proliferation System Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Modification Developmental Process Regulation Of Transcription From RNA Polymerase II Promoter Interkinetic Nuclear Migration Chromatin Organization Regulation Of Stem Cell Proliferation Multicellular Organismal Development Regulation Of Response To DNA Damage Stimulus Positive Regulation Of Transcription, DNA-templated Organ Development Forebrain Development Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Nervous System Development Chromatin Remodeling Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Chromosome Organization Cell Cycle Process Regulation Of RNA Metabolic Process Cell Differentiation Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Mesenchymal Cell Proliferation Nucleus Localization Cell Proliferation In Forebrain Regulation Of Mesenchymal Cell Proliferation Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Telencephalon Development Tube Development Positive Regulation Of Metanephric Cap Mesenchymal Cell Proliferation Cellular Creatinine Homeostasis Cellular Urea Homeostasis Cellular Ammonia Homeostasis Regulation Of Primitive Erythrocyte Differentiation Positive Regulation Of Response To DNA Damage Stimulus ATP-dependent Chromatin Remodeling Brain Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Head Development Positive Regulation Of Cell Proliferation Regulation Of Cell Proliferation	Spindle Stabilization Mitotic Cell Cycle Process Histone Modification Mitotic Cell Cycle Negative Regulation Of Protein Binding Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Histone-serine Phosphorylation Chromatin Modification Cell Cycle Process Negative Regulation Of Binding Mitotic Nuclear Division G2/M Transition Of Mitotic Cell Cycle Chromatin Organization Spindle Organization Regulation Of Protein Stability Regulation Of Protein Binding Cell Cycle Microtubule Cytoskeleton Organization Regulation Of Microtubule-based Process Posttranscriptional Regulation Of Gene Expression Histone Phosphorylation Negative Regulation Of Microtubule Depolymerization Mitotic Spindle Organization Positive Regulation Of Protein Catabolic Process Chromosome Organization Organelle Organization Negative Regulation Of Microtubule Polymerization Or Depolymerization Histone H4 Acetylation Anterior/posterior Pattern Specification Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Cytokinesis Proteasomal Protein Catabolic Process Regulation Of Binding Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Neural Plate Formation Regulation Of Primitive Erythrocyte Differentiation Negative Regulation Of Spindle Checkpoint Positive Regulation Of Metabolic Process Positive Regulation Of Cell Cycle Regulation Of Microtubule Polymerization Or Depolymerization Cell Proliferation Golgi Organization Spindle Assembly Spindle Assembly Involved In Female Meiosis I Serotonin Uptake Lactate Biosynthetic Process From Pyruvate Microtubule-based Process Diencephalon Development Centrosome Organization
Tagcloud ?		12q13 abrogated amplified attenuation bronchial candidate cisplastin cleavage colony contributing conversely copy define helped identifying impairing implicating inducing integrative matched nsclc oncogene oncogenes overexpressed p21waf1 parp reveal rnai senescence	acidic additionally amplification clinicopathological coil coiled correlation cytoplasmic dysregulation fda fish gc her2 immunohistochemistry indicator lymph maybe node occurs positive prognostic resected stage synergistic thought tnm transforming unclear valuable
Tagcloud (Difference) ?		12q13 abrogated amplified attenuation bronchial candidate cisplastin cleavage colony contributing conversely copy define helped identifying impairing implicating inducing integrative matched nsclc oncogene oncogenes overexpressed p21waf1 parp reveal rnai senescence	acidic additionally amplification clinicopathological coil coiled correlation cytoplasmic dysregulation fda fish gc her2 immunohistochemistry indicator lymph maybe node occurs positive prognostic resected stage synergistic thought tnm transforming unclear valuable
Tagcloud (Intersection) ?