PFDN1 and ASNA1

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		PFDN1	ASNA1
Gene Name		prefoldin subunit 1	arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Prefoldin Complex	Nucleus Nucleolus Cytoplasm Endoplasmic Reticulum Extracellular Vesicular Exosome
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Unfolded Protein Binding	Transporter Activity ATP Binding Arsenite Transmembrane Transporter Activity ATPase Activity Metal Ion Binding
	Biological Process	Regulation Of Transcription, DNA-templated Protein Folding Cell Cycle Telencephalon Development Cerebellum Development Actin Cytoskeleton Organization B Cell Activation Cellular Protein Metabolic Process 'de Novo' Posttranslational Protein Folding	Transport Metabolic Process Inorganic Anion Transport Protein Insertion Into ER Membrane
Pathways		Protein folding Prefoldin mediated transfer of substrate to CCT/TriC Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding Chaperonin-mediated protein folding
Drugs			Adenosine triphosphate
Diseases
GWAS
Protein-Protein Interactions		54 interactors: ACTA1 ACTB ALB ASNA1 BRK1 CCDC85A CHGA DCTN1 DEFA1 DGCR14 EDRF1 EIF3C EIF4A2 EOMES EXT2 EZH2 FAM20C GIT1 GPRASP1 HAP1 HIP1 HMGXB3 HOXD8 IFT140 IMMT INPP5K JADE1 KIAA0408 KIAA1377 LRIF1 MED31 NDC80 NR2F1 PDE4DIP PDHB PFDN2 PLXNB2 PRKD2 PSME1 PTN RMI1 RPLP1 RPS28 SEC31A SKP2 SNX5 SPTBN4 SUMO3 SYNDIG1 TERT TTC38 TUBA1A YEATS4 ZNF235	13 interactors: APLN ASPH CACNA1A GPX7 HILPDA PFDN1 SEC61A1 SEC61B STATH STX5 TK1 TTR VAMP2
Entrez ID		5201	439
HPRD ID		05357	03555
Ensembl ID		ENSG00000113068	ENSG00000198356
Uniprot IDs		O60925	O43681
PDB IDs
Enriched GO Terms of Interacting Partners?		Organelle Organization Cellular Localization Cellular Macromolecule Biosynthetic Process Cellular Component Assembly Macromolecule Biosynthetic Process Gene Expression Membrane Organization RNA Biosynthetic Process Cellular Protein Localization Establishment Of Protein Localization To Membrane Protein Localization Developmental Process Cerebral Cortex Regionalization Mitotic Cell Cycle Biosynthetic Process Cellular Process Cytoskeleton-dependent Intracellular Transport Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Cellular Metabolic Process Establishment Of Localization In Cell Anatomical Structure Development RNA Metabolic Process Organelle Localization 'de Novo' Posttranslational Protein Folding Intracellular Transport Cell Cycle Process 'de Novo' Protein Folding Regulation Of Metabolic Process Telencephalon Regionalization Regulation Of Protein Metabolic Process Mitotic Cell Cycle Process Regulation Of Cellular Component Organization Regulation Of Cellular Protein Metabolic Process Protein Localization To Organelle Positive Regulation Of Cellular Metabolic Process Protein Localization To Membrane Vesicle Localization Regulation Of Cilium Assembly Multicellular Organismal Development Regulation Of Cellular Process Regulation Of Mitotic Cell Cycle Phase Transition Anatomical Structure Morphogenesis Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Killing Of Cells Of Other Organism Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Metabolic Process Regulation Of Cell Cycle Phase Transition Anatomical Structure Formation Involved In Morphogenesis	Protein Localization To Membrane Membrane Organization Transport Establishment Of Protein Localization To Membrane Calcium Ion-dependent Exocytosis Secretion Vesicle Fusion Cytoplasmic Transport Acid Secretion Cellular Protein Localization Cerebellar Molecular Layer Development Fetal Process Involved In Parturition Organelle Fusion Vestibular Nucleus Development Skeletal Muscle Cell Proliferation Peptidyl-aspartic Acid Hydroxylation Autocrine Signaling Intracellular Protein Transport SRP-dependent Cotranslational Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Endomembrane System Organization Body Fluid Secretion Neurotransmitter Secretion Golgi Disassembly Cerebellum Maturation Eosinophil Degranulation Musculoskeletal Movement, Spinal Reflex Action Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Cerebellum Development Protein Localization To Endoplasmic Reticulum Gamma-aminobutyric Acid Secretion Metencephalon Development Membrane Fusion Protein Localization Energy Reserve Metabolic Process Regulation Of Neurotransmitter Levels Thyroid Hormone Transport Regulation Of Acetylcholine Secretion, Neurotransmission Retrograde Protein Transport, ER To Cytosol Cell Growth Establishment Of Localization In Cell Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Regulation Of Exocytosis Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Rhythmic Synaptic Transmission Response To Cortisol Thymidine Metabolic Process
Tagcloud ?			als14 als8 amyotrophic anchored anticipated belongs cofactors converts establishes faf1 fedax ffat hexamer homo immunoprecipitates interactors msp oligosaccharyl p97 phenylalanine proficient repertoire rpn2 trc uba ubiquitinated ubx vapa vapb
Tagcloud (Difference) ?			als14 als8 amyotrophic anchored anticipated belongs cofactors converts establishes faf1 fedax ffat hexamer homo immunoprecipitates interactors msp oligosaccharyl p97 phenylalanine proficient repertoire rpn2 trc uba ubiquitinated ubx vapa vapb
Tagcloud (Intersection) ?