YEATS4 and TACC2

Number of citations of the paper that reports this interaction (PMID 12620397)
8

Data Source:
HPRD (in vitro, in vivo)

		YEATS4	TACC2
Gene Name		YEATS domain containing 4	transforming, acidic coiled-coil containing protein 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Nuclear Matrix NuA4 Histone Acetyltransferase Complex	Nucleus Nucleoplasm Nucleolus Cytoplasm Microtubule Organizing Center Microtubule Cytoskeleton
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Structural Constituent Of Cytoskeleton Protein Binding Protein C-terminus Binding	Protein Domain Specific Binding Nuclear Hormone Receptor Binding
	Biological Process	Chromatin Organization Transcription, DNA-templated Mitotic Nuclear Division Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation Positive Regulation Of Transcription, DNA-templated	Microtubule Cytoskeleton Organization Cell Proliferation Cerebral Cortex Development Neurogenesis Interkinetic Nuclear Migration Astral Microtubule Organization Regulation Of Microtubule-based Process
Pathways		Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS		Height ( 18391951) Response to diuretic therapy ( 18591461)	Myopia (pathological) ( 23049088) Obesity-related traits ( 23251661)
Protein-Protein Interactions		14 interactors: CEP162 FRMD4A KDM1A MLLT10 MRGBP MYC MYCN NUMA1 PFDN1 RNF8 SMARCB1 TACC1 TACC2 TFAP2B	11 interactors: AURKC CREBBP EP300 HMG20B KAT2A KAT2B PPP1CC RXRB SMARCB1 UBC YEATS4
Entrez ID		8089	10579
HPRD ID		03666	05600
Ensembl ID		ENSG00000127337	ENSG00000138162
Uniprot IDs		F8W0J4 O95619	D6RAA5 E7EMZ9 E9PBC6 O95359 Q4VXL8
PDB IDs
Enriched GO Terms of Interacting Partners?		Organelle Organization Cell Cycle Anatomical Structure Development Positive Regulation Of Stem Cell Proliferation System Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Modification Developmental Process Regulation Of Transcription From RNA Polymerase II Promoter Interkinetic Nuclear Migration Chromatin Organization Regulation Of Stem Cell Proliferation Multicellular Organismal Development Regulation Of Response To DNA Damage Stimulus Positive Regulation Of Transcription, DNA-templated Organ Development Forebrain Development Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Nervous System Development Chromatin Remodeling Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Chromosome Organization Cell Cycle Process Regulation Of RNA Metabolic Process Cell Differentiation Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Mesenchymal Cell Proliferation Nucleus Localization Cell Proliferation In Forebrain Regulation Of Mesenchymal Cell Proliferation Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Telencephalon Development Tube Development Positive Regulation Of Metanephric Cap Mesenchymal Cell Proliferation Cellular Creatinine Homeostasis Cellular Urea Homeostasis Cellular Ammonia Homeostasis Regulation Of Primitive Erythrocyte Differentiation Positive Regulation Of Response To DNA Damage Stimulus ATP-dependent Chromatin Remodeling Brain Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Head Development Positive Regulation Of Cell Proliferation Regulation Of Cell Proliferation	Chromatin Modification N-terminal Peptidyl-lysine Acetylation Chromatin Organization Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Chromosome Organization Protein Acetylation Histone Modification Positive Regulation Of Transcription, DNA-templated N-terminal Protein Amino Acid Acetylation Cell Cycle Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Peptidyl-lysine Modification Viral Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Rhythmic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia N-terminal Protein Amino Acid Modification Notch Signaling Pathway Mitotic Cell Cycle RNA Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Chromatin Remodeling Gene Expression Regulation Of Gene Expression Peptidyl-amino Acid Modification Histone H4 Acetylation Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Cellular Macromolecule Biosynthetic Process Regulation Of DNA-templated Transcription In Response To Stress Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Gluconeogenesis By Positive Regulation Of Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Cell Cycle Process Regulation Of Cellular Ketone Metabolic Process By Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Gluconeogenesis By Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Type I Interferon Production Mitotic Cell Cycle Process Regulation Of Transcription, DNA-templated Positive Regulation By Host Of Viral Transcription Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process
Tagcloud ?		12q13 abrogated amplified attenuation bronchial candidate cisplastin cleavage colony contributing conversely copy define helped identifying impairing implicating inducing integrative matched nsclc oncogene oncogenes overexpressed p21waf1 parp reveal rnai senescence	abundantly affymetrix annotated ccnd1 crmp1 curing cycles ddc endpoint gabrb3 hurdle hydroxylase immunotherapy isl1 kif1a marrows mrd neuroblastoma phox2b prioritize profiling ranking sampled serves stringent surrogate top u95 uncover
Tagcloud (Difference) ?		12q13 abrogated amplified attenuation bronchial candidate cisplastin cleavage colony contributing conversely copy define helped identifying impairing implicating inducing integrative matched nsclc oncogene oncogenes overexpressed p21waf1 parp reveal rnai senescence	abundantly affymetrix annotated ccnd1 crmp1 curing cycles ddc endpoint gabrb3 hurdle hydroxylase immunotherapy isl1 kif1a marrows mrd neuroblastoma phox2b prioritize profiling ranking sampled serves stringent surrogate top u95 uncover
Tagcloud (Intersection) ?