SETD7 and SIRT1

  • Number of citations of the paper that reports this interaction (PMID 21245319)
  • 26
  • Data Source:
  • BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

SETD7

SIRT1

Gene Name SET domain containing (lysine methyltransferase) 7 sirtuin 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 24 interactors: A1BG DNMT1 E2F1 ESR1 H3F3A HCFC1 HIST1H3A HIST1H4A HIST2H3C HIST3H3 KLF4 L3MBTL1 NR2F2 PPP1R12A PRKAR1A RELA SERTAD1 SIRT1 SOX2 STAT3 STEAP3 TAF10 TAF7 TP53 47 interactors: AKT1 ARNTL BCL11A BHLHE41 CDK6 CSNK2B CTTN EP300 ESRRA FOS FOXO1 FOXO3 GAPDH HES1 HEY2 HIC1 HIST1H1B HIST1H3A HNF4A IRS2 MAPK8 MAPT MYCN NBN NMNAT1 NR1H2 NR1H3 NR1H4 PARP1 PML PPARA PPARGC1A PSME3 RARA RELA RICTOR RRP8 SATB1 SETD7 SMAD7 SNW1 SREBF1 STK11 STK4 TP53 UBE2I VDR
Entrez ID 80854 23411
HPRD ID 16226 08381
Ensembl ID ENSG00000145391 ENSG00000096717
Uniprot IDs Q8WTS6 A8K128 B0QZ35 E9PC49 Q96EB6
PDB IDs 1H3I 1MT6 1MUF 1N6A 1N6C 1O9S 1XQH 2F69 3CBM 3CBO 3CBP 3M53 3M54 3M55 3M56 3M57 3M58 3M59 3M5A 3OS5 3VUZ 3VV0 4E47 4JDS 4JLG 4I5I
Enriched GO Terms of Interacting Partners?
Tagcloud ?
adenosylmethionine  biotinylated  broad  chemoproteomics  coactivator  cofactor  competition  competitive  confluent  derivative  druggable  enantiomer  exhibits  groove  hippo  kit  lysine  mcf7  methyltransferase  methyltransferases  occupying  pfi  phenocopied  pretreated  unusual  validate  valuable  yap  yes 
1alpha  adipose  adrenergic  alternate  atgl  biogenesis  catalyzed  coactivator  coregulator  deacetylase  deacetylation  fatty  identifies  links  lipase  lipolysis  mediates  metabolism  nad  oxidative  partner  peroxisome  pgc  ppar  presumed  proliferator  promote  sirtuin  triglyceride 
Tagcloud (Difference) ?
adenosylmethionine  biotinylated  broad  chemoproteomics  cofactor  competition  competitive  confluent  derivative  druggable  enantiomer  exhibits  groove  hippo  kit  lysine  mcf7  methyltransferase  methyltransferases  occupying  pfi  phenocopied  pretreated  unusual  validate  valuable  yap  yes 
1alpha  adipose  adrenergic  alternate  atgl  biogenesis  catalyzed  coregulator  deacetylase  deacetylation  fatty  identifies  links  lipase  lipolysis  mediates  metabolism  nad  oxidative  partner  peroxisome  pgc  ppar  presumed  proliferator  promote  sirtuin  triglyceride 
Tagcloud (Intersection) ?
coactivator