SETD7 and TAF7

Number of citations of the paper that reports this interaction (PMID 16415881)
49

Data Source:
HPRD (in vitro)

		SETD7	TAF7
Gene Name		SET domain containing (lysine methyltransferase) 7	TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Chromosome Nucleolus	Nucleoplasm Transcription Factor TFIID Complex Golgi Apparatus Positive Transcription Elongation Factor Complex B Transcription Factor TFTC Complex MLL1 Complex
	Molecular Function	P53 Binding Protein Binding Protein-lysine N-methyltransferase Activity Histone-lysine N-methyltransferase Activity	Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Protein Binding Transcription Factor Binding Histone Acetyltransferase Binding Vitamin D Receptor Binding Transcription Regulatory Region DNA Binding Thyroid Hormone Receptor Binding
	Biological Process	Chromatin Organization Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cellular Response To DNA Damage Stimulus Chromatin Modification Peptidyl-lysine Monomethylation Peptidyl-lysine Dimethylation Histone Lysine Methylation Heterochromatin Organization	Negative Regulation Of Transcription From RNA Polymerase II Promoter Spermine Transport DNA-templated Transcription, Initiation Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Protein Kinase Activity Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Histone Acetylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		Chromatin modifying enzymes Chromatin organization PKMTs methylate histone lysines
Drugs
Diseases
GWAS
Protein-Protein Interactions		24 interactors: A1BG DNMT1 E2F1 ESR1 H3F3A HCFC1 HIST1H3A HIST1H4A HIST2H3C HIST3H3 KLF4 L3MBTL1 NR2F2 PPP1R12A PRKAR1A RELA SERTAD1 SIRT1 SOX2 STAT3 STEAP3 TAF10 TAF7 TP53	27 interactors: AHR CDK7 CDK9 CPSF1 FAU GATA1 HIST3H3 HSF1 IKBKG MAP1LC3B RBM6 SETD7 TAF1 TAF10 TAF11 TAF12 TAF15 TAF2 TAF4 TAF5 TAF6 TAF8 TAF9 TRIM22 TRIM24 YWHAE ZSCAN1
Entrez ID		80854	6879
HPRD ID		16226	07196
Ensembl ID		ENSG00000145391	ENSG00000178913
Uniprot IDs		Q8WTS6	Q15545
PDB IDs		1H3I 1MT6 1MUF 1N6A 1N6C 1O9S 1XQH 2F69 3CBM 3CBO 3CBP 3M53 3M54 3M55 3M56 3M57 3M58 3M59 3M5A 3OS5 3VUZ 3VV0 4E47 4JDS 4JLG
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated DNA Methylation On Cytosine Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Gene Expression Chromatin Silencing At RDNA Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Chromatin Organization Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Chromosome Organization Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression, Epigenetic Cellular Nitrogen Compound Metabolic Process Chromatin Silencing Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Gene Silencing Nitrogen Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process DNA Methylation Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process DNA Modification RNA Metabolic Process Regulation Of Gene Expression, Epigenetic Regulation Of Cell Proliferation Positive Regulation Of Metabolic Process Regulation Of Cell Cycle Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Organelle Organization Cellular Metabolic Process Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Intracellular Receptor Signaling Pathway	Transcription Elongation From RNA Polymerase II Promoter DNA-templated Transcription, Elongation Transcription From RNA Polymerase II Promoter Viral Process RNA Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Transcription, DNA-templated RNA Metabolic Process DNA-templated Transcription, Initiation Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Histone Acetylation Internal Peptidyl-lysine Acetylation Cellular Metabolic Process Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Peptidyl-lysine Modification Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Histone Modification Histone H3 Acetylation Chromatin Organization Chromosome Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Modification Positive Regulation Of Metabolic Process Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Viral Transcription Cellular Response To Stress Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Peptidyl-amino Acid Modification
Tagcloud ?		adenosylmethionine biotinylated broad chemoproteomics coactivator cofactor competition competitive confluent derivative druggable enantiomer exhibits groove hippo kit lysine mcf7 methyltransferase methyltransferases occupying pfi phenocopied pretreated unusual validate valuable yap yes	3d acetyltransferase acetyltransferases architecture assembly cofolding displays dissociable ensures heterodimer integral lys27 machinery mark marks multiprotein neighboring nucleates obvious pic pockets preinitiation reading similarities taf1 tata tfiid trimethylated
Tagcloud (Difference) ?		adenosylmethionine biotinylated broad chemoproteomics coactivator cofactor competition competitive confluent derivative druggable enantiomer exhibits groove hippo kit lysine mcf7 methyltransferase methyltransferases occupying pfi phenocopied pretreated unusual validate valuable yap yes	3d acetyltransferase acetyltransferases architecture assembly cofolding displays dissociable ensures heterodimer integral lys27 machinery mark marks multiprotein neighboring nucleates obvious pic pockets preinitiation reading similarities taf1 tata tfiid trimethylated
Tagcloud (Intersection) ?