C1orf35 and CCNL1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		C1orf35	CCNL1
Description		chromosome 1 open reading frame 35	cyclin L1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Secretory Granule Lumen Ficolin-1-rich Granule Lumen	Cyclin-dependent Protein Kinase Holoenzyme Complex Nucleus Nucleoplasm Nuclear Speck
	Molecular Function	RNA Binding Protein Binding	Protein Binding Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity
	Biological Process		Regulation Of Transcription By RNA Polymerase II Regulation Of Apoptotic Process Regulation Of RNA Splicing Regulation Of Centrosome Cycle Regulation Of Cell Cycle
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS			Adiponectin levels in pregnancy ( 28317342) Adult body size ( 32376654) Alanine aminotransferase levels ( 33547301) Anthropometric traits in newborns ( 23575227) Birth weight ( 20372150 23202124 31453325 31043758 27680694) Birth weight variance ( 31453325) Body fat percentage variance ( 31453325) Body mass index ( 26426971) circulating leptin levels ( 32917775 26833098) circulating leptin levels adjusted for BMI ( 26833098 32917775) Coronary artery disease ( 33020668) Diabetic retinopathy ( 21441570) Eating disorders ( 22911880) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Menarche (age at onset) ( 25231870) Offspring birth weight ( 31043758) PR interval ( 32439900 30046033) Smoking cessation in chronic obstructive pulmonary disease ( 21685187)
Interacting Genes		44 interacting genes: AP2M1 APP ARL6IP4 CCNL1 CEP70 CSNK2A1 CT45A1 DACH1 DRC4 DVL3 EXOSC7 FAM133A FXR1 FXR2 GKAP1 GOLGA2 GOLGA6L9 HSF2BP INCA1 LUC7L2 MID2 MIPOL1 MTUS2 NKAPD1 NXF1 PICK1 PLEKHF2 PRPF6 RBMX2 RINT1 RNF151 RP9 SDCBP SDCBP2 SPMIP2 SRPK2 SRRM4 STAC3 TERF1 THAP1 TRIM54 TRIM55 TRIM63 ZRANB1	21 interacting genes: APP APPBP2 C1orf35 CASP8 CDK11A DVL3 FAM133A JMJD6 KRTAP12-2 NKAPD1 PRDM6 PRPF40A RAD51D RNPS1 RSRP1 SORBS3 SREK1IP1 SRSF2 TFIP11 ZRANB1 ZRSR2
Entrez ID		79169	57018
HPRD ID		10090	10814
Ensembl ID		ENSG00000143793	ENSG00000163660
Uniprot IDs		Q9BU76	Q9UK58
PDB IDs
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Protein Binding Nuclear Speck Microtubule Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Receptor Internalization Positive Regulation Of Receptor Internalization Microtubule Binding Frizzled Binding Spliceosomal Complex Assembly Positive Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Receptor-mediated Endocytosis Regulation Of Cell Cycle RNA Splicing Positive Regulation Of Receptor-mediated Endocytosis Protein Homodimerization Activity Negative Regulation Of Long-term Synaptic Potentiation Regulation Of Neuronal Synaptic Plasticity MRNA Binding	RNA Splicing MRNA Processing MRNA Metabolic Process Regulation Of MRNA Processing RNA Processing Regulation Of RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of MRNA Splicing, Via Spliceosome Nucleic Acid Binding
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