STMN2 and TRPC5

Number of citations of the paper that reports this interaction (PMID 12858178)
67

Data Source:
HPRD (in vivo, two hybrid)

		STMN2	TRPC5
Gene Name		stathmin 2	transient receptor potential cation channel, subfamily C, member 5
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Endosome Golgi Apparatus Membrane Lamellipodium Axon Growth Cone Vesicle Neuron Projection Neuronal Cell Body Perinuclear Region Of Cytoplasm	Plasma Membrane Integral Component Of Plasma Membrane Calcium Channel Complex
	Molecular Function	Protein Binding Tubulin Binding Calcium-dependent Protein Binding	Calcium Channel Activity Protein Binding Store-operated Calcium Channel Activity Inositol 1,4,5 Trisphosphate Binding
	Biological Process	Negative Regulation Of Microtubule Depolymerization Positive Regulation Of Neuron Projection Development Negative Regulation Of Neuron Projection Development Negative Regulation Of Microtubule Polymerization Positive Regulation Of Microtubule Depolymerization Cellular Response To Nerve Growth Factor Stimulus	Calcium Ion Transport Nervous System Development Axon Guidance Ion Transmembrane Transport Transmembrane Transport Calcium Ion Transmembrane Transport
Pathways			Ion channel transport Axon guidance Role of second messengers in netrin-1 signaling TRP channels Stimuli-sensing channels Netrin-1 signaling
Drugs
Diseases
GWAS		Creutzfeldt-Jakob disease ( 19081515)	Smoking behavior ( 19247474)
Protein-Protein Interactions		17 interactors: CCDC85A CDK1 CEP70 EEF1A1 GPRASP1 GPRASP2 MAPK10 MAPK3 NGFR PRKACA RGS20 RGS6 SUMO1 TEX11 TFCP2 TRPC5 TXLNA	7 interactors: ITPR3 MX1 SLC9A3R1 STMN2 STMN3 TRPC1 TRPC4
Entrez ID		11075	7224
HPRD ID		09003	02273
Ensembl ID		ENSG00000104435	ENSG00000072315
Uniprot IDs		E5RGX5 Q93045	Q9UL62
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway Nuclear Envelope Organization Neurotrophin Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Regulation Of Signal Transduction MyD88-dependent Toll-like Receptor Signaling Pathway Regulation Of Innate Immune Response Toll-like Receptor 4 Signaling Pathway Cellular Response To Growth Factor Stimulus Activation Of Protein Kinase Activity Regulation Of Signaling Response To Growth Factor Chemotaxis Regulation Of MAP Kinase Activity Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Toll-like Receptor Signaling Pathway Stress-activated MAPK Cascade G2/M Transition Of Mitotic Cell Cycle Stress-activated Protein Kinase Signaling Cascade Nucleus Organization Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Axon Guidance Activation Of MAPK Activity Activation Of Innate Immune Response Innate Immune Response Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of MAPK Cascade Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Response To Epidermal Growth Factor Positive Regulation Of Protein Kinase Activity Positive Regulation Of Innate Immune Response Positive Regulation Of Kinase Activity Cellular Response To Fibroblast Growth Factor Stimulus Positive Regulation Of Catalytic Activity Response To Fibroblast Growth Factor Mitotic Nuclear Envelope Disassembly Axonogenesis Positive Regulation Of MAP Kinase Activity	Calcium Ion Transmembrane Transport Metal Ion Transport Calcium Ion Transport Acid Secretion Cell Projection Organization Cation Transport Regulation Of Microtubule Polymerization Or Depolymerization Cellular Ion Homeostasis Renal Phosphate Ion Absorption Cellular Chemical Homeostasis Ion Homeostasis Response To Calcium Ion Generation Of Neurons Negative Regulation Of Sodium:proton Antiporter Activity Glutathione Transport Secretion Monocarboxylic Acid Transport Neurogenesis Regulation Of Microtubule Cytoskeleton Organization Cellular Homeostasis Ion Transport Regulation Of Microtubule-based Process Gamma-aminobutyric Acid Secretion Cytosolic Calcium Ion Homeostasis Neuron Projection Development Renal Sodium Ion Transport Positive Regulation Of Microtubule Depolymerization Chemical Homeostasis Cellular Phosphate Ion Homeostasis Regulation Of Sodium:proton Antiporter Activity Sensory Perception Of Sweet Taste Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Cation Transmembrane Transport Negative Regulation Of Sodium Ion Transmembrane Transport Negative Regulation Of Rac Protein Signal Transduction Sensory Perception Of Umami Taste Neuron Development Nervous System Development Phospholipase C-activating Dopamine Receptor Signaling Pathway Gamma-aminobutyric Acid Transport Saliva Secretion Bile Acid Secretion Microtubule Depolymerization Cellular Calcium Ion Homeostasis Neuron Differentiation Carboxylic Acid Transport Calcium Ion Homeostasis Organic Acid Transport Oligopeptide Transport Negative Regulation Of Sodium Ion Transport
Tagcloud ?		bcl11a cpg f9 gab1 h3k4me3 h3k9 h3k9me3 hmgcs1 imprinting island k14ac knockout mest mobp modifications permissive rara raralpha rars recapitulated ref2l repressive rlf1 rpl39l rxralpha slc38a4 tcfap2a tex13 transcript	allosteric ankyrin arises belongs branched channels detectors enthalpy evolved gating kcal macroscopic melastatin polymodal specialized subfamilies tetramers thermal trpa trpa1 trpm trpm8 trpv trpv1 trpv3 vanilloid voltage
Tagcloud (Difference) ?		bcl11a cpg f9 gab1 h3k4me3 h3k9 h3k9me3 hmgcs1 imprinting island k14ac knockout mest mobp modifications permissive rara raralpha rars recapitulated ref2l repressive rlf1 rpl39l rxralpha slc38a4 tcfap2a tex13 transcript	allosteric ankyrin arises belongs branched channels detectors enthalpy evolved gating kcal macroscopic melastatin polymodal specialized subfamilies tetramers thermal trpa trpa1 trpm trpm8 trpv trpv1 trpv3 vanilloid voltage
Tagcloud (Intersection) ?