ANXA7 and CLEC3B

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		ANXA7	CLEC3B
Description		annexin A7	C-type lectin domain family 3 member B
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Membrane Plasma Membrane Vesicle Membrane Membrane Extracellular Matrix Chromaffin Granule Membrane Extracellular Exosome	Granular Component Extracellular Region Extracellular Space Cytoplasm Extracellular Matrix Platelet Dense Granule Lumen Extracellular Exosome
	Molecular Function	Phosphatidylserine Binding RNA Binding Integrin Binding Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Calcium-dependent Protein Binding	Calcium Ion Binding Heparin Binding Carbohydrate Binding Kringle Domain Binding
	Biological Process	Autophagy Negative Regulation Of Gene Expression Epithelial Cell Differentiation Response To Calcium Ion Membrane Fusion Response To Phorbol 13-acetate 12-myristate	Ossification Positive Regulation Of Plasminogen Activation Bone Mineralization
Pathways			Platelet degranulation
Drugs			Tenecteplase Lanoteplase Copper
Diseases
GWAS		Copper levels ( 26025379)	Acne (severe) ( 24927181) Alzheimer's disease ( 33654092) Blood protein levels ( 30072576)
Interacting Genes		109 interacting genes: A1BG A2M ACTB ACTL6B ADAMTS10 ANGPT2 APC APLP1 ATP5F1B ATP6V1A ATXN3 BAG6 CCDC90B CCT7 CDK4 CELF3 CENPB CHGB CLEC3B COL11A2 COL4A2 COL4A5 COPS6 CPNE2 CPNE6 CREBBP CRMP1 CSAD CTSB DDAH2 DMPK DOCK7 DVL1 DYNC1I1 EEF1A1 ERG28 EXT2 F13A1 FAF1 FBN3 FGB FLAD1 GAPDH GBP2 GDF9 GNB2 GNB5 HADHB HMGXB3 HOXD8 HUNK INPP5K INTS11 KLHL23 KMT2B LRIF1 MED31 MPPED1 MSH2 NGFR NMT2 NPRL2 OGT OTUB1 PAAF1 PAX8 PDCD6 PDHB PKM PLD3 PRKACA PRKCA PRKCB PRKCG PRKG1 PSMB10 QARS1 RBBP4 RBM48 RPL13 RPS2 S100A10 SDF4 SEMA5B SETDB1 SMPD1 SP110 SRC SRI SUMO3 TAF5L TIAM2 TLE1 TMEM108 TMSB4X TRMT2A TUBA1A TUBB2B TUBB3 UBE2D1 UCHL5 UNC119 USP4 VIM WDR18 WDR73 ZBTB16 ZNF135 ZNF431	12 interacting genes: ANXA7 APP CDKN1A GADD45A GSK3B HGF PLAT PLG RPS6KA6 RPS6KB1 SH3GL2 TK1
Entrez ID		310	7123
HPRD ID		01720	01759
Ensembl ID		ENSG00000138279	ENSG00000163815
Uniprot IDs		B2R657 P20073	E9PHK0 P05452
PDB IDs		8W5S	1HTN 1RJH 1TN3 3L9J
Enriched GO Terms of Interacting Partners?		TORC1 Signaling Extracellular Exosome TOR Signaling Negative Regulation Of TOR Signaling Negative Regulation Of TORC1 Signaling Regulation Of TORC1 Signaling Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity Regulation Of TOR Signaling Positive Regulation Of Metabolic Process Positive Regulation Of TORC1 Signaling Positive Regulation Of Macromolecule Metabolic Process Regulation Of Stem Cell Population Maintenance Cytoplasm Regulation Of Primary Metabolic Process Protein Modification By Small Protein Removal Extracellular Matrix Positive Regulation Of Biosynthetic Process Positive Regulation Of TOR Signaling Developmental Process Regulation Of Metabolic Process Macromolecule Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Perinuclear Region Of Cytoplasm Regulation Of Protein Metabolic Process Protein Deubiquitination Cellular Response To Nutrient Levels Regulation Of Proteolysis Histone H3T6 Kinase Activity Structural Constituent Of Cytoskeleton Positive Regulation Of Protein Metabolic Process Platelet Alpha Granule Lumen Signal Transduction Positive Regulation Of Macromolecule Biosynthetic Process Protein Metabolic Process Blood Microparticle Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Protein Catabolic Process Cytoplasmic Translation Diacylglycerol-dependent Serine/threonine Kinase Activity Cytosol Nuclear Matrix Response To Interleukin-1 Response To Cytokine Regulation Of Protein Localization Negative Regulation Of Signal Transduction Calyx Of Held Negative Regulation Of Translational Initiation Protein Kinase C Signaling Proteasomal Protein Catabolic Process	Negative Regulation Of Multicellular Organismal Process Negative Regulation Of TORC2 Signaling Trans-synaptic Signaling By BDNF, Modulating Synaptic Transmission Trans-synaptic Signaling By BDNF Negative Regulation Of Gene Expression Regulation Of Extrinsic Apoptotic Signaling Pathway Platelet Alpha Granule Lumen Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Reactive Oxygen Species Metabolic Process Modulation Of Chemical Synaptic Transmission Negative Regulation Of Metabolic Process Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle TOR Signaling Negative Regulation Of Fibrinolysis Trans-synaptic Signaling, Modulating Synaptic Transmission Glutamatergic Synapse Cellular Response To Growth Factor Stimulus Regulation Of TORC2 Signaling Regulation Of Multicellular Organismal Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Extrinsic Apoptotic Signaling Pathway TORC2 Signaling Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Negative Regulation Of Biosynthetic Process Apolipoprotein Binding Response To Growth Factor Regulation Of Fibrinolysis Regulation Of MAPK Cascade Fibrinolysis Negative Regulation Of Macromolecule Metabolic Process Developmental Growth Signaling Receptor Binding Central Nervous System Development Regulation Of Reactive Oxygen Species Metabolic Process Molecular Function Activator Activity Protein Serine/threonine Kinase Binding Regulation Of Apoptotic Signaling Pathway Regulation Of Cell Communication Regulation Of Signaling Mitotic Cell Cycle Phase Transition Signal Transduction In Response To DNA Damage Serine-type Endopeptidase Activity Positive Regulation Of Blood Coagulation Negative Regulation Of Catalytic Activity Cell Cycle Phase Transition Positive Regulation Of Coagulation Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Intracellular Signal Transduction Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
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