ANXA7 and SRI

Number of citations of the paper that reports this interaction (PubMedID 9268363)
0

Data Source:
BioGRID (far western blotting, far western blotting)
HPRD (in vitro)

		ANXA7	SRI
Description		annexin A7	sorcin
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Membrane Plasma Membrane Vesicle Membrane Membrane Extracellular Matrix Chromaffin Granule Membrane Extracellular Exosome	Nucleoplasm Cytoplasm Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Membrane Sarcoplasmic Reticulum Z Disc T-tubule Vesicle Sarcoplasmic Reticulum Membrane Chromaffin Granule Membrane Extracellular Exosome
	Molecular Function	Phosphatidylserine Binding RNA Binding Integrin Binding Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Calcium-dependent Protein Binding	Protease Binding Signaling Receptor Binding Calcium Channel Regulator Activity Calcium Ion Binding Protein Binding Identical Protein Binding Transmembrane Transporter Binding Metal Ion Binding Protein Heterodimerization Activity DNA-binding Transcription Factor Binding Protein Sequestering Activity Transcription Regulator Inhibitor Activity
	Biological Process	Autophagy Negative Regulation Of Gene Expression Epithelial Cell Differentiation Response To Calcium Ion Membrane Fusion Response To Phorbol 13-acetate 12-myristate	Calcium Ion Transport Signal Transduction Negative Regulation Of Heart Rate Regulation Of Gene Expression Regulation Of Cell Communication By Electrical Coupling Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Calcium Ion Transport Negative Regulation Of Cardiac Muscle Contraction Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Regulation Of Cardiac Muscle Cell Contraction Regulation Of Relaxation Of Muscle Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction
Pathways			Stimuli-sensing channels Reduction of cytosolic Ca++ levels Sodium/Calcium exchangers Ion homeostasis Ion transport by P-type ATPases
Drugs			Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS		Copper levels ( 26025379)
Interacting Genes		109 interacting genes: A1BG A2M ACTB ACTL6B ADAMTS10 ANGPT2 APC APLP1 ATP5F1B ATP6V1A ATXN3 BAG6 CCDC90B CCT7 CDK4 CELF3 CENPB CHGB CLEC3B COL11A2 COL4A2 COL4A5 COPS6 CPNE2 CPNE6 CREBBP CRMP1 CSAD CTSB DDAH2 DMPK DOCK7 DVL1 DYNC1I1 EEF1A1 ERG28 EXT2 F13A1 FAF1 FBN3 FGB FLAD1 GAPDH GBP2 GDF9 GNB2 GNB5 HADHB HMGXB3 HOXD8 HUNK INPP5K INTS11 KLHL23 KMT2B LRIF1 MED31 MPPED1 MSH2 NGFR NMT2 NPRL2 OGT OTUB1 PAAF1 PAX8 PDCD6 PDHB PKM PLD3 PRKACA PRKCA PRKCB PRKCG PRKG1 PSMB10 QARS1 RBBP4 RBM48 RPL13 RPS2 S100A10 SDF4 SEMA5B SETDB1 SMPD1 SP110 SRC SRI SUMO3 TAF5L TIAM2 TLE1 TMEM108 TMSB4X TRMT2A TUBA1A TUBB2B TUBB3 UBE2D1 UCHL5 UNC119 USP4 VIM WDR18 WDR73 ZBTB16 ZNF135 ZNF431	25 interacting genes: ALG2 ANXA11 ANXA7 ATP2A2 CACNA1C CACNA1S CALCOCO2 GCA GRIK1 MORC3 MTNR1A NRAS PDE4C PRR13 PSEN2 RYR2 RYR3 SHBG SIGMAR1 SMAD2 SNCA SRPK2 STAT3 TCF12 USHBP1
Entrez ID		310	6717
HPRD ID		01720	01680
Ensembl ID		ENSG00000138279	ENSG00000075142
Uniprot IDs		B2R657 P20073	B4DHQ6 P30626
PDB IDs		8W5S	1JUO 2JC2 4U8D 4UPG 4USL 5MRA
Enriched GO Terms of Interacting Partners?		TORC1 Signaling Extracellular Exosome TOR Signaling Negative Regulation Of TOR Signaling Negative Regulation Of TORC1 Signaling Regulation Of TORC1 Signaling Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity Regulation Of TOR Signaling Positive Regulation Of Metabolic Process Positive Regulation Of TORC1 Signaling Positive Regulation Of Macromolecule Metabolic Process Regulation Of Stem Cell Population Maintenance Cytoplasm Regulation Of Primary Metabolic Process Protein Modification By Small Protein Removal Extracellular Matrix Positive Regulation Of Biosynthetic Process Positive Regulation Of TOR Signaling Developmental Process Regulation Of Metabolic Process Macromolecule Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Perinuclear Region Of Cytoplasm Regulation Of Protein Metabolic Process Protein Deubiquitination Cellular Response To Nutrient Levels Regulation Of Proteolysis Histone H3T6 Kinase Activity Structural Constituent Of Cytoskeleton Positive Regulation Of Protein Metabolic Process Platelet Alpha Granule Lumen Signal Transduction Positive Regulation Of Macromolecule Biosynthetic Process Protein Metabolic Process Blood Microparticle Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Protein Catabolic Process Cytoplasmic Translation Diacylglycerol-dependent Serine/threonine Kinase Activity Cytosol Nuclear Matrix Response To Interleukin-1 Response To Cytokine Regulation Of Protein Localization Negative Regulation Of Signal Transduction Calyx Of Held Negative Regulation Of Translational Initiation Protein Kinase C Signaling Proteasomal Protein Catabolic Process	Sarcoplasmic Reticulum Calcium Ion Transport Regulation Of Sequestering Of Calcium Ion Cellular Response To Purine-containing Compound Cellular Response To Caffeine Response To Caffeine Intracellular Signaling Cassette Sarcoplasmic Reticulum Monoatomic Ion Channel Activity Calcium-mediated Signaling Regulation Of Cardiac Muscle Cell Action Potential Calcium Ion Transmembrane Transport Calcium Ion Transmembrane Import Into Cytosol Calcium Channel Activity Response To Alkaloid Ryanodine-sensitive Calcium-release Channel Activity Calcium Ion Homeostasis Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Calcium Ion Binding Cellular Response To Alkaloid Calcium-induced Calcium Release Activity Sarcoplasmic Reticulum Membrane Calcium Ion Transport Muscle System Process Response To Calcium Ion Mitochondrion-endoplasmic Reticulum Membrane Tethering Regulation Of Calcium Ion Transmembrane Transport Intracellularly Gated Calcium Channel Activity Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Action Potential Release Of Sequestered Calcium Ion Into Cytosol Negative Regulation Of Sequestering Of Calcium Ion L-type Voltage-gated Calcium Channel Complex Response To Metal Ion Regulation Of Muscle Contraction Intracellular Signal Transduction Release Of Sequestered Calcium Ion Into Cytosol By Endoplasmic Reticulum Regulation Of Ventricular Cardiac Muscle Cell Action Potential Cellular Response To Epinephrine Stimulus Calcium Ion Transport Into Cytosol High Voltage-gated Calcium Channel Activity Calmodulin Binding S100 Protein Binding Muscle Contraction Regulation Of Cardiac Muscle Contraction Response To Epinephrine Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Cell Communication By Electrical Coupling Involved In Cardiac Conduction Striated Muscle Contraction Regulation Of Hydrogen Peroxide Metabolic Process Response To Magnesium Ion
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