ANXA7 and PDCD6

Number of citations of the paper that reports this interaction (PubMedID 12445460)
0

Data Source:
HPRD (in vitro)

		ANXA7	PDCD6
Description		annexin A7	programmed cell death 6
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Membrane Plasma Membrane Vesicle Membrane Membrane Extracellular Matrix Chromaffin Granule Membrane Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol ER To Golgi Transport Vesicle Membrane Membrane COPII Vesicle Coat Cytoplasmic Vesicle Cul3-RING Ubiquitin Ligase Complex Perinuclear Region Of Cytoplasm Extracellular Exosome Endoplasmic Reticulum Exit Site
	Molecular Function	Phosphatidylserine Binding RNA Binding Integrin Binding Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Calcium-dependent Protein Binding	Magnesium Ion Binding Calcium Ion Binding Protein Binding Protein-macromolecule Adaptor Activity Identical Protein Binding Protein Homodimerization Activity Protein-membrane Adaptor Activity Metal Ion Binding Protein Heterodimerization Activity Protein Dimerization Activity Calcium-dependent Protein Binding Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	Autophagy Negative Regulation Of Gene Expression Epithelial Cell Differentiation Response To Calcium Ion Membrane Fusion Response To Phorbol 13-acetate 12-myristate	Angiogenesis Positive Regulation Of Endothelial Cell Proliferation Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Apoptotic Process Positive Regulation Of Endothelial Cell Migration Neural Crest Formation Neural Crest Cell Development Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of TOR Signaling Cellular Response To Heat Vascular Endothelial Growth Factor Receptor-2 Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Angiogenesis COPII Vesicle Coating Response To Calcium Ion Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Apoptotic Signaling Pathway Positive Regulation Of Protein Monoubiquitination
Pathways
Drugs			Calcium Zinc Calcium citrate Calcium Phosphate Calcium phosphate dihydrate Zinc acetate
Diseases
GWAS		Copper levels ( 26025379)	Hip circumference adjusted for BMI ( 34021172) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		109 interacting genes: A1BG A2M ACTB ACTL6B ADAMTS10 ANGPT2 APC APLP1 ATP5F1B ATP6V1A ATXN3 BAG6 CCDC90B CCT7 CDK4 CELF3 CENPB CHGB CLEC3B COL11A2 COL4A2 COL4A5 COPS6 CPNE2 CPNE6 CREBBP CRMP1 CSAD CTSB DDAH2 DMPK DOCK7 DVL1 DYNC1I1 EEF1A1 ERG28 EXT2 F13A1 FAF1 FBN3 FGB FLAD1 GAPDH GBP2 GDF9 GNB2 GNB5 HADHB HMGXB3 HOXD8 HUNK INPP5K INTS11 KLHL23 KMT2B LRIF1 MED31 MPPED1 MSH2 NGFR NMT2 NPRL2 OGT OTUB1 PAAF1 PAX8 PDCD6 PDHB PKM PLD3 PRKACA PRKCA PRKCB PRKCG PRKG1 PSMB10 QARS1 RBBP4 RBM48 RPL13 RPS2 S100A10 SDF4 SEMA5B SETDB1 SMPD1 SP110 SRC SRI SUMO3 TAF5L TIAM2 TLE1 TMEM108 TMSB4X TRMT2A TUBA1A TUBB2B TUBB3 UBE2D1 UCHL5 UNC119 USP4 VIM WDR18 WDR73 ZBTB16 ZNF135 ZNF431	29 interacting genes: ANXA11 ANXA7 BAG4 CDKN2A CEBPA CPNE1 CPNE2 CPNE4 DIAPH3 FAS FASLG FNDC3A HEBP2 IGFALS KLHL12 MAP3K5 MAPK1IP1L MIA2 PDCD6IP PEF1 PRR19 SARAF SEC31A SH3KBP1 SHISA4 TIMM22 UBC VPS37C YWHAQ
Entrez ID		310	10016
HPRD ID		01720	03035
Ensembl ID		ENSG00000138279	ENSG00000249915
Uniprot IDs		B2R657 P20073	A0A024QZ42 A0A087WZ38 O75340 Q53FC3
PDB IDs		8W5S	2ZN8 2ZN9 2ZND 2ZNE 2ZRS 2ZRT 3AAJ 3AAK 3WXA 5GQQ
Enriched GO Terms of Interacting Partners?		TORC1 Signaling Extracellular Exosome TOR Signaling Negative Regulation Of TOR Signaling Negative Regulation Of TORC1 Signaling Regulation Of TORC1 Signaling Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity Regulation Of TOR Signaling Positive Regulation Of Metabolic Process Positive Regulation Of TORC1 Signaling Positive Regulation Of Macromolecule Metabolic Process Regulation Of Stem Cell Population Maintenance Cytoplasm Regulation Of Primary Metabolic Process Protein Modification By Small Protein Removal Extracellular Matrix Positive Regulation Of Biosynthetic Process Positive Regulation Of TOR Signaling Developmental Process Regulation Of Metabolic Process Macromolecule Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Perinuclear Region Of Cytoplasm Regulation Of Protein Metabolic Process Protein Deubiquitination Cellular Response To Nutrient Levels Regulation Of Proteolysis Histone H3T6 Kinase Activity Structural Constituent Of Cytoskeleton Positive Regulation Of Protein Metabolic Process Platelet Alpha Granule Lumen Signal Transduction Positive Regulation Of Macromolecule Biosynthetic Process Protein Metabolic Process Blood Microparticle Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Protein Catabolic Process Cytoplasmic Translation Diacylglycerol-dependent Serine/threonine Kinase Activity Cytosol Nuclear Matrix Response To Interleukin-1 Response To Cytokine Regulation Of Protein Localization Negative Regulation Of Signal Transduction Calyx Of Held Negative Regulation Of Translational Initiation Protein Kinase C Signaling Proteasomal Protein Catabolic Process	Response To Metal Ion Calcium-dependent Protein Binding Response To Calcium Ion Calcium-dependent Phospholipid Binding Extracellular Exosome COPII Vesicle Coat Endoplasmic Reticulum Exit Site Vesicle Membrane Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Neural Crest Formation Necroptotic Signaling Pathway Vesicle-mediated Transport Phosphatidylserine Binding ESCRT I Complex Vesicle Organization Cellular Response To Metal Ion Replicative Senescence Cellular Response To Calcium Ion Programmed Necrotic Cell Death Cellular Response To Tumor Necrosis Factor Viral Budding Via Host ESCRT Complex Membrane Organization COPII Vesicle Coating Cellular Localization Viral Budding Autophagy Lymphocyte Apoptotic Process T Cell Apoptotic Process NF-kappaB Binding Ligase Inhibitor Activity Response To Tumor Necrosis Factor RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Vesicle Cargo Loading Golgi Vesicle Transport TERT-RMRP Complex Template-free RNA Nucleotidyltransferase Positive Regulation Of Transdifferentiation RNA-directed RNA Polymerase Complex SiRNA Transcription Negative Regulation Of MRNA Modification Multivesicular Body Organization Multivesicular Body Assembly Stem Cell Development Neural Crest Cell Development Vesicle Coating Stereocilia Tip-link Density COPII-coated ER To Golgi Transport Vesicle Cytokinetic Process Apoptotic Signaling Pathway
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