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FBXL18 and WWP2
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
FBXL18
WWP2
Gene Name
F-box and leucine-rich repeat protein 18
WW domain containing E3 ubiquitin protein ligase 2
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Ubiquitin Ligase Complex
Nucleus
Cytoplasm
Membrane
Extracellular Vesicular Exosome
Molecular Function
RNA Polymerase II Transcription Factor Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Transcription Factor Binding
Ligase Activity
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Cellular Protein Modification Process
Negative Regulation Of Gene Expression
Protein Ubiquitination
Negative Regulation Of Transporter Activity
Regulation Of Ion Transmembrane Transport
Regulation Of Membrane Potential
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Negative Regulation Of Transcription, DNA-templated
Viral Entry Into Host Cell
Negative Regulation Of Protein Transport
Protein Autoubiquitination
Protein K63-linked Ubiquitination
Regulation Of Potassium Ion Transmembrane Transporter Activity
Pathways
Drugs
Diseases
GWAS
IgE levels (
23146381
)
Protein-Protein Interactions
21 interactors:
CALCOCO2
FHL3
GOLGA2
HNRNPK
KRT40
KRTAP10-3
KRTAP4-12
MDFI
MID2
MTUS2
NOTCH2NL
PLSCR1
PNMA1
PSMA3
PSTPIP1
RBPMS
TFCP2
TRAF1
TRAF4
WWP1
WWP2
53 interactors:
ANKRD44
ARRDC1
ATN1
CDC34
CLCN5
CPSF6
DAG1
DIDO1
EGR2
EWSR1
FAM189A2
FBXL18
HNRNPUL1
IL2RG
IL6R
LGALS9B
NDFIP2
PAIP1
PDLIM7
POLR2A
POU5F1
RASA1
RNF11
RUSC1
SCAMP3
SCN5A
SCNN1A
SCNN1B
SCNN1G
SF1
SFTPC
SMAD3
SMAD7
SNRPC
SPG20
TFAP2A
TNK2
TP53BP2
TRAF4
UBC
UBE2D2
UBE2D3
UBE2E1
UBE2E3
UBE2J2
UBE2K
UBE2L3
USP7
VASP
VPS37C
WBP1
WBP2
WIPF1
Entrez ID
80028
11060
HPRD ID
07753
03812
Ensembl ID
ENSG00000155034
ENSG00000198373
Uniprot IDs
F5H4Z4
Q96ME1
B4DHF6
O00308
PDB IDs
Enriched GO Terms of Interacting Partners
?
Viral Process
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Viral Entry Into Host Cell
Entry Into Host Cell
Regulation Of Nitrogen Compound Metabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Regulation Of Binding
Proteasomal Protein Catabolic Process
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Positive Regulation Of Protein Metabolic Process
Regulation Of RNA Biosynthetic Process
Negative Regulation Of Viral Process
Positive Regulation Of Signal Transduction
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of RNA Metabolic Process
Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Signal Transduction
Defense Response
Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity
Negative Regulation Of Binding
Response To Stimulus
Interaction With Host
Immune System Process
Positive Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process
Regulation Of Gene Expression
Positive Regulation Of JNK Cascade
Positive Regulation Of Protein Modification Process
Inflammatory Response
Regulation Of Signaling
Positive Regulation Of NF-kappaB Transcription Factor Activity
Positive Regulation Of Stress-activated MAPK Cascade
Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade
Apoptotic Process
Phosphatidylserine Biosynthetic Process
Regulation Of Metabolic Process
Programmed Cell Death
Ubiquitin-dependent Protein Catabolic Process
Regulation Of Protein Binding
Modification-dependent Protein Catabolic Process
Regulation Of Viral Process
Cell Death
Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process
Protein Localization To Microtubule
Death
Regulation Of JNK Cascade
Regulation Of Cellular Process
Proteolysis Involved In Cellular Protein Catabolic Process
Protein Polyubiquitination
Protein K48-linked Ubiquitination
Protein Modification By Small Protein Conjugation
Protein Ubiquitination
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Response To Stimulus
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Proteasomal Protein Catabolic Process
Transcription Initiation From RNA Polymerase II Promoter
Excretion
Response To Organic Substance
DNA-templated Transcription, Initiation
Transcription From RNA Polymerase II Promoter
Positive Regulation Of Protein Ubiquitination
Positive Regulation Of Cellular Protein Metabolic Process
Protein K11-linked Ubiquitination
Sodium Ion Homeostasis
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Gene Expression
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Cellular Metabolic Process
RNA Metabolic Process
Transcription, DNA-templated
Regulation Of Ubiquitin-protein Transferase Activity
Cellular Response To Stimulus
Positive Regulation Of Ossification
Regulation Of Ossification
RNA Biosynthetic Process
Regulation Of Protein Ubiquitination
Apoptotic Signaling Pathway
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Positive Regulation Of Protein Modification Process
Regulation Of Ventricular Cardiac Muscle Cell Membrane Depolarization
Regulation Of Cellular Protein Metabolic Process
Viral Process
Apoptotic Process
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Regulation Of Protein Catabolic Process
RNA Processing
Multicellular Organismal Water Homeostasis
Programmed Cell Death
Negative Regulation Of Transcription By Competitive Promoter Binding
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Proteolysis
Transforming Growth Factor Beta Receptor Signaling Pathway
Tagcloud
?
accelerating
anticancer
biomarker
cascade
catalyzes
contributes
counterparts
deleted
dramatic
e3
encodes
final
homologue
ligase
ligases
malignancies
member
nedd4
neoplastic
oscc
osccs
pi3k
promotion
pten
ten
tensin
tumoral
ubiquitination
Tagcloud (Difference)
?
accelerating
anticancer
biomarker
cascade
catalyzes
contributes
counterparts
deleted
dramatic
e3
encodes
final
homologue
ligase
ligases
malignancies
member
nedd4
neoplastic
oscc
osccs
pi3k
promotion
pten
ten
tensin
tumoral
ubiquitination
Tagcloud (Intersection)
?