SYNDIG1 and TLCD4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SYNDIG1	TLCD4
Description		synapse differentiation inducing 1	TLC domain containing 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endosome Plasma Membrane Postsynaptic Density Membrane Dendrite Synaptic Vesicle Membrane Early Endosome Membrane Cell Projection Dendritic Spine Dendritic Shaft Intracellular Membrane-bounded Organelle Cell Body Synapse Postsynaptic Membrane Excitatory Synapse Postsynaptic Density Membrane Glutamatergic Synapse	Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding Glutamate Receptor Binding Protein Homodimerization Activity	Protein Binding
	Biological Process	Intracellular Protein Transport Positive Regulation Of Synapse Assembly Synaptic Vesicle Clustering Regulation Of Postsynapse Assembly	Lipid Homeostasis
Pathways
Drugs
Diseases
GWAS		LDL cholesterol levels in HIV infection ( 33109212) Sucrose liking ( 31005972)
Interacting Genes		16 interacting genes: AQP6 ELOVL4 FATE1 FFAR2 GPR42 GPRC5D LEPROTL1 MAL MFSD6 PFDN1 SLC16A13 SLC35H1 SLC41A1 TLCD4 TMEM43 UNC93B1	72 interacting genes: ADGRB3 ADGRE2 ARV1 ATP13A1 BNIP3 CACNG1 CCDC167 CDIPT CFTR CHPT1 CLCN7 CLEC7A CMTM5 COMT CTXN3 CXCL16 CYP4F2 CYP4F22 DHRSX EBP EMC6 EMP1 ERG28 FA2H FDFT1 FXYD6 FXYD6-FXYD2 GJB2 GOSR2 GYPA HMOX1 IGFBP5 KRT1 LNPEP MS4A13 MYG1 NAT8 NDUFA3 NINJ1 NKG7 ORMDL1 PMP22 PRAF2 PRRT2 REEP6 SCAMP5 SCD SEC22A SEC22B SERP1 SFXN1 SFXN3 SLC41A1 SLC67A1 SMAGP STATH STX12 SYNDIG1 SYNJ2BP TIMM23 TMEM115 TMEM120B TMEM19 TMEM229B TMEM237 TMEM60 TMIE TVP23B UBE2J1 VEZT YIPF1 YIPF4
Entrez ID		79953	148534
HPRD ID		12766	08110
Ensembl ID		ENSG00000101463	ENSG00000152078
Uniprot IDs		Q9H7V2	Q96MV1
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Sterol Biosynthetic Process Lipid Biosynthetic Process Cholesterol Biosynthetic Process SNAP Receptor Activity Steroid Biosynthetic Process Membrane Fusion Serine Import Into Mitochondrion Lipid Metabolic Process Sterol Metabolic Process Cholesterol Transport Establishment Of Protein Localization Sterol Transport Membrane Organization Organic Cation Transport Import Into The Mitochondrion Protein Transport L-serine Transmembrane Transporter Activity L-serine Transport Protein Binding Bleb Assembly Serine Transport Vesicle Fusion
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