TLCD4 and TMEM19

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TLCD4	TMEM19
Description		TLC domain containing 4	transmembrane protein 19
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane	Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Lipid Homeostasis
Pathways
Drugs
Diseases
GWAS			Nonsyndromic cleft lip with cleft palate ( 28232668)
Interacting Genes		72 interacting genes: ADGRB3 ADGRE2 ARV1 ATP13A1 BNIP3 CACNG1 CCDC167 CDIPT CFTR CHPT1 CLCN7 CLEC7A CMTM5 COMT CTXN3 CXCL16 CYP4F2 CYP4F22 DHRSX EBP EMC6 EMP1 ERG28 FA2H FDFT1 FXYD6 FXYD6-FXYD2 GJB2 GOSR2 GYPA HMOX1 IGFBP5 KRT1 LNPEP MS4A13 MYG1 NAT8 NDUFA3 NINJ1 NKG7 ORMDL1 PMP22 PRAF2 PRRT2 REEP6 SCAMP5 SCD SEC22A SEC22B SERP1 SFXN1 SFXN3 SLC41A1 SLC67A1 SMAGP STATH STX12 SYNDIG1 SYNJ2BP TIMM23 TMEM115 TMEM120B TMEM19 TMEM229B TMEM237 TMEM60 TMIE TVP23B UBE2J1 VEZT YIPF1 YIPF4	38 interacting genes: APOA5 AQP6 BSCL2 C10orf67 CD3G CD79A CNR2 CPLX4 CREB3 CREB3L1 ELOVL4 FAM210B FCER1G GJB1 GORAB GPR42 GPRC5D GPX8 HSD17B13 KASH5 LDAF1 LEPROTL1 LY6E MC4R PGRMC2 PIGP PTGES REEP4 RNF185 SERTM1 SLC71A2 SLC7A1 SUSD6 TEX29 TLCD4 TMEM139 TMEM14B TMEM45A
Entrez ID		148534	55266
HPRD ID		08110	15530
Ensembl ID		ENSG00000152078	ENSG00000139291
Uniprot IDs		Q96MV1	Q96HH6
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Sterol Biosynthetic Process Lipid Biosynthetic Process Cholesterol Biosynthetic Process SNAP Receptor Activity Steroid Biosynthetic Process Membrane Fusion Serine Import Into Mitochondrion Lipid Metabolic Process Sterol Metabolic Process Cholesterol Transport Establishment Of Protein Localization Sterol Transport Membrane Organization Organic Cation Transport Import Into The Mitochondrion Protein Transport L-serine Transmembrane Transporter Activity L-serine Transport Protein Binding Bleb Assembly Serine Transport Vesicle Fusion	Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Protein Binding
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