TLCD4 and DHRSX

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TLCD4	DHRSX
Description		TLC domain containing 4	dehydrogenase/reductase X-linked
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane	Extracellular Region Lipid Droplet
	Molecular Function	Protein Binding	Protein Binding Oxidoreductase Activity Polyprenol Dehydrogenase (NAD+) Activity Dolichal Reductase (NADPH) Activity
	Biological Process	Lipid Homeostasis	Positive Regulation Of Autophagy Dolichyl Monophosphate Biosynthetic Process
Pathways			Synthesis of dolichyl-phosphate
Drugs
Diseases
GWAS
Interacting Genes		72 interacting genes: ADGRB3 ADGRE2 ARV1 ATP13A1 BNIP3 CACNG1 CCDC167 CDIPT CFTR CHPT1 CLCN7 CLEC7A CMTM5 COMT CTXN3 CXCL16 CYP4F2 CYP4F22 DHRSX EBP EMC6 EMP1 ERG28 FA2H FDFT1 FXYD6 FXYD6-FXYD2 GJB2 GOSR2 GYPA HMOX1 IGFBP5 KRT1 LNPEP MS4A13 MYG1 NAT8 NDUFA3 NINJ1 NKG7 ORMDL1 PMP22 PRAF2 PRRT2 REEP6 SCAMP5 SCD SEC22A SEC22B SERP1 SFXN1 SFXN3 SLC41A1 SLC67A1 SMAGP STATH STX12 SYNDIG1 SYNJ2BP TIMM23 TMEM115 TMEM120B TMEM19 TMEM229B TMEM237 TMEM60 TMIE TVP23B UBE2J1 VEZT YIPF1 YIPF4	20 interacting genes: APOC1 APP AQP6 ASPH ATXN1 CIDEB CMTM5 FADS3 GCNT3 HSD17B11 PGRMC2 PIGP RETREG3 RUSF1 TLCD4 TMEM143 TMEM14B TMEM31 TMEM86B ZDHHC15
Entrez ID		148534	207063
HPRD ID		08110	16803
Ensembl ID		ENSG00000152078	ENSG00000169084
Uniprot IDs		Q96MV1	Q8N5I4
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Sterol Biosynthetic Process Lipid Biosynthetic Process Cholesterol Biosynthetic Process SNAP Receptor Activity Steroid Biosynthetic Process Membrane Fusion Serine Import Into Mitochondrion Lipid Metabolic Process Sterol Metabolic Process Cholesterol Transport Establishment Of Protein Localization Sterol Transport Membrane Organization Organic Cation Transport Import Into The Mitochondrion Protein Transport L-serine Transmembrane Transporter Activity L-serine Transport Protein Binding Bleb Assembly Serine Transport Vesicle Fusion	Endoplasmic Reticulum Membrane Very-low-density Lipoprotein Particle Assembly
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