SYNDIG1 and PFDN1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		SYNDIG1	PFDN1
Description		synapse differentiation inducing 1	prefoldin subunit 1
Image		No pdb structure
GO Annotations	Cellular Component	Endosome Plasma Membrane Postsynaptic Density Membrane Dendrite Synaptic Vesicle Membrane Early Endosome Membrane Cell Projection Dendritic Spine Dendritic Shaft Intracellular Membrane-bounded Organelle Cell Body Synapse Postsynaptic Membrane Excitatory Synapse Postsynaptic Density Membrane Glutamatergic Synapse	Cytoplasm Prefoldin Complex Protein-containing Complex
	Molecular Function	Protein Binding Glutamate Receptor Binding Protein Homodimerization Activity	Amyloid-beta Binding Protein Binding Protein Folding Chaperone Unfolded Protein Binding
	Biological Process	Intracellular Protein Transport Positive Regulation Of Synapse Assembly Synaptic Vesicle Clustering Regulation Of Postsynapse Assembly	Protein Folding Negative Regulation Of Amyloid Fibril Formation
Pathways			Prefoldin mediated transfer of substrate to CCT/TriC
Drugs
Diseases
GWAS		LDL cholesterol levels in HIV infection ( 33109212) Sucrose liking ( 31005972)	Alzheimer's disease ( 28183528) Alzheimer's disease in APOE e4- carriers ( 25778476) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Reaction time ( 29844566)
Interacting Genes		16 interacting genes: AQP6 ELOVL4 FATE1 FFAR2 GPR42 GPRC5D LEPROTL1 MAL MFSD6 PFDN1 SLC16A13 SLC35H1 SLC41A1 TLCD4 TMEM43 UNC93B1	55 interacting genes: ACTA1 ACTB ALB BRK1 CCDC85A CEBPA CEP126 CHGA DCTN1 DEFA1 DMAP1 EDRF1 EIF3C EIF4A2 EOMES ESS2 EXT2 EZH2 FAM20C GET3 GIT1 GPRASP1 HAP1 HIP1 HMGXB3 HOXD8 IFT140 IMMT INPP5K JADE1 KIAA0408 LRIF1 MED31 NDC80 NR2F1 PDE4DIP PDHB PFDN2 PLXNB2 PRKD2 PSME1 PTN RMI1 RPLP1 RPS28 SEC31A SKP2 SNX5 SPTBN4 SUMO3 SYNDIG1 TERT TTC38 YEATS4 ZNF235
Entrez ID		79953	5201
HPRD ID		12766	05357
Ensembl ID		ENSG00000101463	ENSG00000113068
Uniprot IDs		Q9H7V2	O60925
PDB IDs			6NR8 6NR9 6NRB 6NRC 6NRD 7WU7
Enriched GO Terms of Interacting Partners?		Membrane	Positive Regulation Of Microtubule Nucleation Structural Constituent Of Cytoskeleton Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Microtubule Nucleation Nuclear Matrix Positive Regulation Of DNA Recombination NuA4 Histone Acetyltransferase Complex Regulation Of Cell Cycle Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Microtubule Polymerization Positive Regulation Of Double-strand Break Repair Intracellular Protein Localization Regulation Of Cell Cycle G1/S Phase Transition Positive Regulation Of Cytoskeleton Organization Regulation Of Supramolecular Fiber Organization Glutamate Receptor Binding Regulation Of Cellular Component Organization
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