EPM2A and PRKAA2

  • Number of citations of the paper that reports this interaction (PMID 18029386)
  • 31
  • Data Source:
  • BioGRID (two hybrid, affinity chromatography technology, enzymatic study)

EPM2A

PRKAA2

Gene Name epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) protein kinase, AMP-activated, alpha 2 catalytic subunit
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 7 interactors: EPM2AIP1 NFU1 NHLRC1 PPP1R3D PRKAA1 PRKAA2 PRKAB2 48 interactors: ABI2 ACACA ACACB AES AIMP2 APPBP2 C19orf47 CCNB1IP1 EEF2K EPM2A FOS GLI1 HMBOX1 HNF4A HOMEZ KCTD1 KIF24 KIFC3 KRT31 KRTAP10-3 L3MBTL3 LEP MYOZ1 NECAB2 NONO NOTCH2NL NRAP NUTM1 PBXIP1 PFKFB2 PRKAB1 PRKAB2 PRKAG1 RBPMS RFX6 RPTOR SNW1 STK11 TCF4 TMOD1 TRIP6 TSC22D4 UBE2I USHBP1 VPS52 WWP1 ZBTB8A ZNF397
Entrez ID 7957 5563
HPRD ID 06345 02735
Ensembl ID ENSG00000112425 ENSG00000162409
Uniprot IDs O95278 P54646
PDB IDs 2H6D 2LTU 2YZA 3AQV
Enriched GO Terms of Interacting Partners?
Tagcloud ?
arms  autophago  biogenesis  branched  chop  defects  disposal  encode  epilepsy  epm2b  glycogen  hyperphosphorylated  insoluble  knock  lafora  laforin  laforinmalin  lamp1  lc3  lysosomal  malin  myoclonus  overaccumulation  proteasomal  s6  slight  speculate  starvation  ubiquitinated 
amyloidogenesis  apmk  appswe  arc  biogenesis  functionality  igf1  igf2  igfbp2  igfr  impairments  insoluble  insr  intolerant  irs1  irs2  nrf1  oxphos  pampk  pgc  pgc1  plaque  precede  ps1  ps1de9  reinforce  sensors  tfam  thr172 
Tagcloud (Difference) ?
arms  autophago  branched  chop  defects  disposal  encode  epilepsy  epm2b  glycogen  hyperphosphorylated  knock  lafora  laforin  laforinmalin  lamp1  lc3  lysosomal  malin  myoclonus  overaccumulation  proteasomal  s6  slight  speculate  starvation  ubiquitinated 
amyloidogenesis  apmk  appswe  arc  functionality  igf1  igf2  igfbp2  igfr  impairments  insr  intolerant  irs1  irs2  nrf1  oxphos  pampk  pgc  pgc1  plaque  precede  ps1  ps1de9  reinforce  sensors  tfam  thr172 
Tagcloud (Intersection) ?
biogenesis  insoluble