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PRRC2A and CPSF1
Number of citations of the paper that reports this interaction (PubMedID
14667819
)
0
Data Source:
HPRD
(two hybrid)
PRRC2A
CPSF1
Description
proline rich coiled-coil 2A
cleavage and polyadenylation specific factor 1
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Plasma Membrane
Membrane
Extracellular Exosome
Nucleus
Nucleoplasm
MRNA Cleavage And Polyadenylation Specificity Factor Complex
Molecular Function
RNA Binding
Protein Binding
Nucleic Acid Binding
RNA Binding
Protein Binding
Enzyme Binding
MRNA 3'-UTR AU-rich Region Binding
Biological Process
Cell Differentiation
MRNA Processing
RNA 3'-end Processing
Co-transcriptional RNA 3'-end Processing, Cleavage And Polyadenylation Pathway
Pathways
Transport of Mature mRNA Derived from an Intronless Transcript
tRNA processing in the nucleus
mRNA 3'-end processing
Processing of Capped Intron-Containing Pre-mRNA
RNA Polymerase II Transcription Termination
Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS
A body shape index (
34021172
)
Adult body size (
32376654
)
Age at first birth (
34211149
)
Anxiety (
33859377
)
Asthma (
31619474
)
Asthma (childhood onset) (
31619474
)
Asthma and major depressive disorder (
31619474
)
Autism spectrum disorder or schizophrenia (
28540026
)
Childhood body mass index (
33045005
)
Hand grip strength (
29691431
)
Height (
28552196
)
Hemoglobin levels (
32327693
)
Hip circumference adjusted for BMI (
34021172
)
Inflammatory bowel disease (
28067908
)
Leukocyte telomere length (
32109421
)
Malaria (
31844061
)
Menopause (age at onset) (
22267201
)
Metabolite levels (
31628463
)
Platelet distribution width (
32888494
)
Schizophrenia (
23894747
)
Systolic blood pressure (
30578418
)
Ulcerative colitis (
28067908
)
Waist circumference (
31928498
)
Waist-hip index (
34021172
)
Waist-to-hip ratio adjusted for BMI (
34021172
)
Educational attainment (
25201988
)
Interacting Genes
32 interacting genes:
ATN1
ATXN1
C1QBP
CCR10
CEBPA
CPSF1
DDX20
EIF3E
EWSR1
FGA
GANAB
GORASP2
GRB2
HNRNPA1
HNRNPM
IFT88
IMMT
JUN
MAD2L2
MAN2C1
NEIL3
P4HA2
PRMT2
PSMA3
QARS1
RBFOX1
RBM11
RERE
RUNX1
SRPK2
SSR3
UBAP2L
58 interacting genes:
CSTF2T
GLIS2
HMOX1
IL7R
INCA1
MCM2
MIR1-2
MIR106B
MIR107
MIR122
MIR128-2
MIR138-1
MIR138-2
MIR143
MIR155
MIR15A
MIR15B
MIR16-2
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200C
MIR205
MIR206
MIR20B
MIR21
MIR214
MIR221
MIR29A
MIR31
MIR34A
MIR34B
MIR7-1
MIR92A1
MIR92A2
MIR98
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7E
MIRLET7F2
MIRLET7G
MIRLET7I
NEDD4
PAPOLA
POLR2A
PRRC2A
REL
TAF11
TAF12
TAF13
TAF5
TAF7
UBC
Entrez ID
7916
29894
HPRD ID
00807
05823
Ensembl ID
ENSG00000204469
ENSG00000071894
Uniprot IDs
A0A1U9X974
A0A1U9X985
A0A1U9X998
A0A1U9X999
A0A1U9X9A9
P48634
Q10570
PDB IDs
6BLY
6BM0
6DNH
6F9N
6FUW
6URG
6URO
8E3I
8E3Q
8R8R
Enriched GO Terms of Interacting Partners
?
Nucleoplasm
RNA Binding
MRNA Metabolic Process
MRNA Processing
Regulation Of MRNA Splicing, Via Spliceosome
RNA Splicing
RNA Metabolic Process
Protein Domain Specific Binding
Regulation Of MRNA Processing
Nucleic Acid Metabolic Process
Nucleic Acid Binding
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Macromolecule Biosynthetic Process
RNA Processing
Negative Regulation Of Biosynthetic Process
Regulation Of RNA Splicing
Negative Regulation Of RNA Metabolic Process
Negative Regulation Of Macromolecule Metabolic Process
Nucleobase-containing Compound Metabolic Process
Nuclear Matrix
Regulation Of RNA Metabolic Process
Negative Regulation Of Metabolic Process
Nucleolus
Nucleus
Regulation Of Alternative MRNA Splicing, Via Spliceosome
Negative Regulation Of Transcription By RNA Polymerase II
Hydrolase Activity, Acting On Glycosyl Bonds
Regulation Of MRNA Metabolic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Gene Expression
Transcription Corepressor Activity
Regulation Of Macromolecule Biosynthetic Process
Poly(U) RNA Binding
Macromolecule Metabolic Process
Regulation Of Primary Metabolic Process
Hematopoietic Stem Cell Proliferation
Alternative MRNA Splicing, Via Spliceosome
MRNA Binding
Negative Regulation Of Double-strand Break Repair Via Homologous Recombination
Positive Regulation Of Macromolecule Biosynthetic Process
Adrenergic Receptor Binding
Cellular Response To Stress
RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding
Negative Regulation Of Blood Coagulation, Common Pathway
Guanyl-nucleotide Exchange Factor Adaptor Activity
Insulin-like Growth Factor Receptor Signaling Pathway
Histone H3R8 Methyltransferase Activity
DNA Damage Response, Signal Transduction Resulting In Transcription
RISC Complex
MiRNA-mediated Post-transcriptional Gene Silencing
Regulatory NcRNA-mediated Post-transcriptional Gene Silencing
Post-transcriptional Gene Silencing
Regulatory NcRNA-mediated Gene Silencing
MRNA Base-pairing Post-transcriptional Repressor Activity
Post-transcriptional Regulation Of Gene Expression
Negative Regulation Of Gene Expression
MRNA 3'-UTR Binding
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
MiRNA-mediated Gene Silencing By Inhibition Of Translation
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Metabolic Process
Extracellular Vesicle
MiRNA-mediated Gene Silencing By MRNA Destabilization
Regulation Of Angiogenesis
Regulation Of Gene Expression
Regulation Of Vasculature Development
Negative Regulation Of Cytokine Production
Regulation Of Macromolecule Biosynthetic Process
Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Angiogenesis
Negative Regulation Of Vasculature Development
Regulation Of Metabolic Process
Negative Regulation Of Cell Migration
Negative Regulation Of Translation
Negative Regulation Of Cell Motility
Negative Regulation Of Locomotion
MRNA Destabilization
RNA Destabilization
Positive Regulation Of MRNA Catabolic Process
Regulation Of Endothelial Cell Migration
Negative Regulation Of Multicellular Organismal Process
Regulation Of Blood Vessel Endothelial Cell Migration
Negative Regulation Of Endothelial Cell Migration
Positive Regulation Of MRNA Metabolic Process
Negative Regulation Of Blood Vessel Endothelial Cell Migration
Regulation Of Cytokine Production
Negative Regulation Of Vascular Endothelial Growth Factor Production
Regulation Of Anatomical Structure Morphogenesis
Negative Regulation Of Protein Metabolic Process
Regulation Of MRNA Stability
Negative Regulation Of Signal Transduction
Regulation Of Endothelial Cell Proliferation
Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Regulation Of RNA Stability
Extracellular Space
Regulation Of Translation
Negative Regulation Of Cell Communication
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Tagcloud (Intersection)
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