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CPSF1 and MCM2
Number of citations of the paper that reports this interaction (PMID
12392551
)
11
Data Source:
HPRD
(in vitro)
CPSF1
MCM2
Gene Name
cleavage and polyadenylation specific factor 1, 160kDa
minichromosome maintenance complex component 2
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
MRNA Cleavage And Polyadenylation Specificity Factor Complex
Chromatin
Nucleus
Nucleoplasm
Nuclear Origin Of Replication Recognition Complex
Cytoplasm
Microtubule Cytoskeleton
MCM Complex
Molecular Function
MRNA 3'-UTR Binding
Protein Binding
DNA Binding
DNA Helicase Activity
DNA Replication Origin Binding
Protein Binding
ATP Binding
Histone Binding
Metal Ion Binding
Biological Process
MRNA Splicing, Via Spliceosome
Transcription From RNA Polymerase II Promoter
Termination Of RNA Polymerase II Transcription
MRNA Polyadenylation
MRNA Cleavage
MRNA Export From Nucleus
RNA Splicing
Gene Expression
MRNA 3'-end Processing
G1/S Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
DNA Replication
DNA Unwinding Involved In DNA Replication
DNA Replication Initiation
DNA Strand Elongation Involved In DNA Replication
Nucleosome Assembly
Cell Cycle
Cellular Response To Interleukin-4
Pathways
Processing of Capped Intron-Containing Pre-mRNA
mRNA Splicing
Transport of Mature mRNA Derived from an Intronless Transcript
RNA Polymerase II Transcription
Transport of Mature mRNAs Derived from Intronless Transcripts
Cleavage of Growing Transcript in the Termination Region
mRNA Splicing - Major Pathway
mRNA 3'-end processing
Processing of Intronless Pre-mRNAs
Processing of Capped Intronless Pre-mRNA
Transport of Mature Transcript to Cytoplasm
RNA Polymerase II Transcription Termination
Synthesis of DNA
G2/M Checkpoints
Activation of the pre-replicative complex
DNA Replication Pre-Initiation
M/G1 Transition
Regulation of DNA replication
Activation of the pre-replicative complex
Orc1 removal from chromatin
S Phase
DNA strand elongation
Cell Cycle, Mitotic
Assembly of the pre-replicative complex
Orc1 removal from chromatin
G1/S Transition
Activation of ATR in response to replication stress
Cell Cycle Checkpoints
Removal of licensing factors from origins
Mitotic G1-G1/S phases
Switching of origins to a post-replicative state
Unwinding of DNA
Drugs
Diseases
GWAS
Protein-Protein Interactions
18 interactors:
CSTF2T
CSTF3
CTD
GLIS2
HMOX1
IL7R
MCM2
NEDD4
PAPOLA
POLR2A
PRRC2A
REL
RRAGA
TAF11
TAF12
TAF13
TAF5
TAF7
47 interactors:
AKAP8
APP
ATM
ATR
CCNB2
CCNC
CDC6
CDC7
CDK2
CDK4
CDK6
CDKN2A
CPSF1
CSNK2A1
DBF4
ELL
GNB5
GTF2B
GTF2H1
HIST3H3
KAT7
MCM10
MCM3
MCM4
MCM5
MCM6
MCM7
MCPH1
MOB4
MPP3
ORC1
ORC2
ORC4
ORC5
ORC6
P2RX4
PHC2
PLK1
RAD52
RPA1
RPA2
RPA3
RPS4X
TBP
TCEA2
TERF1
TERF2IP
Entrez ID
29894
4171
HPRD ID
05823
00303
Ensembl ID
ENSG00000071894
ENSG00000073111
Uniprot IDs
Q10570
P49736
PDB IDs
Enriched GO Terms of Interacting Partners
?
Transcription From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
DNA-templated Transcription, Elongation
DNA-templated Transcription, Initiation
Viral Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Transcription, DNA-templated
RNA Biosynthetic Process
Cellular Nitrogen Compound Metabolic Process
RNA Metabolic Process
Gene Expression
Nitrogen Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Macromolecule Biosynthetic Process
Biosynthetic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Metabolic Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
MRNA Processing
RNA Polyadenylation
Positive Regulation Of Macromolecule Biosynthetic Process
Cellular Metabolic Process
Positive Regulation Of Gene Expression
Termination Of RNA Polymerase II Transcription
MRNA Metabolic Process
Positive Regulation Of Cellular Biosynthetic Process
Positive Regulation Of Viral Transcription
RNA Processing
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Regulation Of DNA-templated Transcription In Response To Stress
Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage
Spermine Transport
Transmission Of Virus
Development Involved In Symbiotic Interaction
Positive Regulation Of Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Cytokine Biosynthetic Process
Regulation Of Viral Transcription
Response To Cytokine
Intracellular Steroid Hormone Receptor Signaling Pathway
Positive Regulation Of Viral Process
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
G1/S Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle Process
DNA Replication
Mitotic Cell Cycle
Cell Cycle Process
DNA Metabolic Process
Cell Cycle
DNA-dependent DNA Replication
DNA Replication Initiation
Nucleobase-containing Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Nitrogen Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
DNA Strand Elongation Involved In DNA Replication
DNA Strand Elongation
Biosynthetic Process
Chromosome Organization
Regulation Of Mitotic Cell Cycle Phase Transition
Regulation Of Cell Cycle
Regulation Of Cell Cycle Phase Transition
Regulation Of Mitotic Cell Cycle
Cellular Metabolic Process
DNA Recombinase Assembly
Telomere Maintenance
Regulation Of Cell Cycle Process
Double-strand Break Repair Via Homologous Recombination
Recombinational Repair
Positive Regulation Of Cell Cycle Process
Regulation Of Cellular Response To Heat
Positive Regulation Of Cell Cycle
Telomere Maintenance Via Telomere Lengthening
Cell Division
Cell Cycle Checkpoint
Double-strand Break Repair
Organelle Organization
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Regulation Of Cell Cycle G2/M Phase Transition
Cellular Response To DNA Damage Stimulus
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Nucleotide-excision Repair, DNA Damage Removal
Regulation Of Mitotic Metaphase/anaphase Transition
Positive Regulation Of Mitotic Cell Cycle Phase Transition
Positive Regulation Of Cell Cycle Phase Transition
Positive Regulation Of Mitotic Cell Cycle
Negative Regulation Of Cell Cycle
Tagcloud
?
1alpha
1beta
bcl2
carcinogenic
ccr2
cervices
e2
epithelia
hek293
hpv16
ikappabalpha
inflammation
intact
integration
isomerase
mediators
peptidyl
pin1
potentiated
prolyl
rela
sdf
ser727
squamous
stat3
stromal
supports
survivin
transformed
Tagcloud (Difference)
?
1alpha
1beta
bcl2
carcinogenic
ccr2
cervices
e2
epithelia
hek293
hpv16
ikappabalpha
inflammation
intact
integration
isomerase
mediators
peptidyl
pin1
potentiated
prolyl
rela
sdf
ser727
squamous
stat3
stromal
supports
survivin
transformed
Tagcloud (Intersection)
?