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CPSF1 and PRRC2A
Number of citations of the paper that reports this interaction (PMID
14667819
)
24
Data Source:
HPRD
(two hybrid)
CPSF1
PRRC2A
Gene Name
cleavage and polyadenylation specific factor 1, 160kDa
proline-rich coiled-coil 2A
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
MRNA Cleavage And Polyadenylation Specificity Factor Complex
Nucleus
Cytoplasm
Membrane
Intracellular Membrane-bounded Organelle
Extracellular Vesicular Exosome
Molecular Function
MRNA 3'-UTR Binding
Protein Binding
Protein Binding
Poly(A) RNA Binding
Biological Process
MRNA Splicing, Via Spliceosome
Transcription From RNA Polymerase II Promoter
Termination Of RNA Polymerase II Transcription
MRNA Polyadenylation
MRNA Cleavage
MRNA Export From Nucleus
RNA Splicing
Gene Expression
MRNA 3'-end Processing
Pathways
Processing of Capped Intron-Containing Pre-mRNA
mRNA Splicing
Transport of Mature mRNA Derived from an Intronless Transcript
RNA Polymerase II Transcription
Transport of Mature mRNAs Derived from Intronless Transcripts
Cleavage of Growing Transcript in the Termination Region
mRNA Splicing - Major Pathway
mRNA 3'-end processing
Processing of Intronless Pre-mRNAs
Processing of Capped Intronless Pre-mRNA
Transport of Mature Transcript to Cytoplasm
RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS
Menopause (age at onset) (
22267201
)
Schizophrenia (
23894747
)
Protein-Protein Interactions
18 interactors:
CSTF2T
CSTF3
CTD
GLIS2
HMOX1
IL7R
MCM2
NEDD4
PAPOLA
POLR2A
PRRC2A
REL
RRAGA
TAF11
TAF12
TAF13
TAF5
TAF7
27 interactors:
ATN1
ATXN1
C1QBP
CCR10
CPSF1
DDX20
EIF3E
EWSR1
FGA
GANAB
GORASP2
GRB2
HNRNPA1
HNRNPM
IFT88
IMMT
JUN
MAD2L2
MAN2C1
P4HA2
PRMT2
PSMA3
QARS
RBFOX1
RERE
SSR3
UBAP2L
Entrez ID
29894
7916
HPRD ID
05823
00807
Ensembl ID
ENSG00000071894
ENSG00000204469
Uniprot IDs
Q10570
P48634
PDB IDs
Enriched GO Terms of Interacting Partners
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Transcription From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
DNA-templated Transcription, Elongation
DNA-templated Transcription, Initiation
Viral Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Transcription, DNA-templated
RNA Biosynthetic Process
Cellular Nitrogen Compound Metabolic Process
RNA Metabolic Process
Gene Expression
Nitrogen Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Macromolecule Biosynthetic Process
Biosynthetic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Metabolic Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
MRNA Processing
RNA Polyadenylation
Positive Regulation Of Macromolecule Biosynthetic Process
Cellular Metabolic Process
Positive Regulation Of Gene Expression
Termination Of RNA Polymerase II Transcription
MRNA Metabolic Process
Positive Regulation Of Cellular Biosynthetic Process
Positive Regulation Of Viral Transcription
RNA Processing
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Regulation Of DNA-templated Transcription In Response To Stress
Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage
Spermine Transport
Transmission Of Virus
Development Involved In Symbiotic Interaction
Positive Regulation Of Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Cytokine Biosynthetic Process
Regulation Of Viral Transcription
Response To Cytokine
Intracellular Steroid Hormone Receptor Signaling Pathway
Positive Regulation Of Viral Process
Gene Expression
MRNA Metabolic Process
RNA Splicing
RNA Metabolic Process
RNA Processing
MRNA Processing
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Nucleocytoplasmic Transport
Nuclear Transport
Heterocycle Metabolic Process
Nitrogen Compound Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Cytoplasmic Transport
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Transcription, DNA-templated
Signal Transduction In Response To DNA Damage
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of RNA Biosynthetic Process
Cellular Aromatic Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway
Nuclear Export
Nuclear Import
Negative Regulation Of Protein Metabolic Process
Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
RNA Transport
Negative Regulation Of Mitotic Cell Cycle Phase Transition
RNA Localization
Regulation Of Substrate Adhesion-dependent Cell Spreading
Cellular Metabolic Process
Ribonucleoprotein Complex Assembly
Negative Regulation Of Signal Transduction
Glutaminyl-tRNA Aminoacylation
Negative Regulation Of Blood Coagulation, Common Pathway
Blood Coagulation, Common Pathway
Cellular Response To Potassium Ion Starvation
Negative Regulation Of DNA Binding
Negative Regulation Of Signaling
Regulation Of Cell Morphogenesis
Innate Immune Response
Negative Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Regulation Of Mitotic Cell Cycle Phase Transition
Negative Regulation Of Mitotic Cell Cycle
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