PRRC2A and UBAP2L

Number of citations of the paper that reports this interaction (PMID 14667819)
24

Data Source:
HPRD (two hybrid)

		PRRC2A	UBAP2L
Gene Name		proline-rich coiled-coil 2A	ubiquitin associated protein 2-like
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Membrane Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome	Ada2/Gcn5/Ada3 Transcription Activator Complex
	Molecular Function	Protein Binding Poly(A) RNA Binding	Protein Binding Poly(A) RNA Binding
	Biological Process		Binding Of Sperm To Zona Pellucida
Pathways
Drugs
Diseases
GWAS		Menopause (age at onset) ( 22267201) Schizophrenia ( 23894747)
Protein-Protein Interactions		27 interactors: ATN1 ATXN1 C1QBP CCR10 CPSF1 DDX20 EIF3E EWSR1 FGA GANAB GORASP2 GRB2 HNRNPA1 HNRNPM IFT88 IMMT JUN MAD2L2 MAN2C1 P4HA2 PRMT2 PSMA3 QARS RBFOX1 RERE SSR3 UBAP2L	6 interactors: ATXN1 ITCH NEDD4 PLXNA2 PRRC2A ZP3
Entrez ID		7916	9898
HPRD ID		00807	06665
Ensembl ID		ENSG00000204469	ENSG00000143569
Uniprot IDs		P48634	F8W726 Q14157
PDB IDs
Enriched GO Terms of Interacting Partners?		Gene Expression MRNA Metabolic Process RNA Splicing RNA Metabolic Process RNA Processing MRNA Processing Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Nucleocytoplasmic Transport Nuclear Transport Heterocycle Metabolic Process Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Cytoplasmic Transport MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Signal Transduction In Response To DNA Damage Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of RNA Biosynthetic Process Cellular Aromatic Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Nuclear Export Nuclear Import Negative Regulation Of Protein Metabolic Process Positive Regulation Of Substrate Adhesion-dependent Cell Spreading RNA Transport Negative Regulation Of Mitotic Cell Cycle Phase Transition RNA Localization Regulation Of Substrate Adhesion-dependent Cell Spreading Cellular Metabolic Process Ribonucleoprotein Complex Assembly Negative Regulation Of Signal Transduction Glutaminyl-tRNA Aminoacylation Negative Regulation Of Blood Coagulation, Common Pathway Blood Coagulation, Common Pathway Cellular Response To Potassium Ion Starvation Negative Regulation Of DNA Binding Negative Regulation Of Signaling Regulation Of Cell Morphogenesis Innate Immune Response Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle	Protein K63-linked Ubiquitination Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Interaction With Host Cerebellar Granule Cell Precursor Tangential Migration Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Positive Regulation Of Acrosomal Vesicle Exocytosis Positive Regulation Of Ovarian Follicle Development Positive Regulation Of Antral Ovarian Follicle Growth Transmission Of Virus Positive Regulation Of Type IV Hypersensitivity Development Involved In Symbiotic Interaction Negative Regulation Of Cellular Metabolic Process Regulation Of T Cell Proliferation Hindbrain Tangential Cell Migration Egg Coat Formation Cellular Localization Protein Polyubiquitination Regulation Of Ovarian Follicle Development Intracellular Receptor Signaling Pathway Signaling Negative Regulation Of Binding Of Sperm To Zona Pellucida Positive Regulation Of Phosphatidylinositol Biosynthetic Process Positive Regulation Of Protein Catabolic Process Regulation Of Signal Transduction Cell Communication Negative Regulation Of Signal Transduction Negative Regulation Of Transcription, DNA-templated Protein K29-linked Ubiquitination Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Signaling Regulation Of Protein Deubiquitination Positive Regulation Of Acrosome Reaction Positive Regulation Of Phospholipid Biosynthetic Process Positive Regulation Of T Cell Anergy Progesterone Receptor Signaling Pathway Adaptive Immune Response Positive Regulation Of Protein Metabolic Process Regulation Of Membrane Potential Regulation Of Signaling Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Locomotion Immune Response Regulation Of T Cell Activation Positive Regulation Of Hypersensitivity Regulation Of Phosphorylation Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Glucocorticoid Receptor Signaling Pathway Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway
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