CPSF1 and TAF13

Number of citations of the paper that reports this interaction (PubMedID 9311784)
0

Data Source:
HPRD (in vitro)

		CPSF1	TAF13
Description		cleavage and polyadenylation specific factor 1	TATA-box binding protein associated factor 13
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GO Annotations	Cellular Component	Nucleus Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex	Nucleus Nucleoplasm Transcription Factor TFIID Complex Nucleolus
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding Enzyme Binding MRNA 3'-UTR AU-rich Region Binding	DNA Binding Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity TBP-class Protein Binding Protein Heterodimerization Activity
	Biological Process	MRNA Processing RNA 3'-end Processing Co-transcriptional RNA 3'-end Processing, Cleavage And Polyadenylation Pathway	DNA-templated Transcription Initiation Transcription By RNA Polymerase II Transcription Initiation At RNA Polymerase II Promoter MRNA Transcription By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II
Pathways		Transport of Mature mRNA Derived from an Intronless Transcript tRNA processing in the nucleus mRNA 3'-end processing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs	HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
GWAS		Educational attainment ( 25201988)
Interacting Genes		58 interacting genes: CSTF2T GLIS2 HMOX1 IL7R INCA1 MCM2 MIR1-2 MIR106B MIR107 MIR122 MIR128-2 MIR138-1 MIR138-2 MIR143 MIR155 MIR15A MIR15B MIR16-2 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200C MIR205 MIR206 MIR20B MIR21 MIR214 MIR221 MIR29A MIR31 MIR34A MIR34B MIR7-1 MIR92A1 MIR92A2 MIR98 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7E MIRLET7F2 MIRLET7G MIRLET7I NEDD4 PAPOLA POLR2A PRRC2A REL TAF11 TAF12 TAF13 TAF5 TAF7 UBC	7 interacting genes: CPSF1 H3-4 MTUS2 TAF10 TAF11 TAF15 TBP
Entrez ID		29894	6884
HPRD ID		05823	11864
Ensembl ID		ENSG00000071894	ENSG00000197780
Uniprot IDs		Q10570	Q15543
PDB IDs		6BLY 6BM0 6DNH 6F9N 6FUW 6URG 6URO 8E3I 8E3Q 8R8R	1BH8 1BH9 6MZD 6MZL 7EDX 7EG7 7EG8 7EG9 7EGA 7EGB 7EGC 7EGD 7EGE 7EGF 7EGI 7EGJ 7ENA 7ENC 8GXQ 8GXS 8WAK 8WAL 8WAN 8WAO 8WAP 8WAQ 8WAR 8WAS
Enriched GO Terms of Interacting Partners?		RISC Complex MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Extracellular Vesicle MiRNA-mediated Gene Silencing By MRNA Destabilization Regulation Of Angiogenesis Regulation Of Gene Expression Regulation Of Vasculature Development Negative Regulation Of Cytokine Production Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Regulation Of Metabolic Process Negative Regulation Of Cell Migration Negative Regulation Of Translation Negative Regulation Of Cell Motility Negative Regulation Of Locomotion MRNA Destabilization RNA Destabilization Positive Regulation Of MRNA Catabolic Process Regulation Of Endothelial Cell Migration Negative Regulation Of Multicellular Organismal Process Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Endothelial Cell Migration Positive Regulation Of MRNA Metabolic Process Negative Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Cytokine Production Negative Regulation Of Vascular Endothelial Growth Factor Production Regulation Of Anatomical Structure Morphogenesis Negative Regulation Of Protein Metabolic Process Regulation Of MRNA Stability Negative Regulation Of Signal Transduction Regulation Of Endothelial Cell Proliferation Regulation Of Cell Migration Involved In Sprouting Angiogenesis Regulation Of RNA Stability Extracellular Space Regulation Of Translation Negative Regulation Of Cell Communication	MRNA Transcription By RNA Polymerase II Transcription Factor TFIID Complex RNA Polymerase II General Transcription Initiation Factor Activity Protein-DNA Complex Assembly RNA Polymerase II Preinitiation Complex Assembly Transcription Initiation At RNA Polymerase II Promoter MRNA Transcription Transcription Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II DNA-templated Transcription Initiation Regulation Of DNA-templated Transcription Initiation MRNA Metabolic Process Transcription By RNA Polymerase II Male Germ Cell Nucleus SAGA Complex Assembly Enzyme Binding DNA-templated Transcription Nucleoplasm Lateral Mesodermal Cell Differentiation Protein-containing Complex Assembly Nucleus RNA Metabolic Process Protein-containing Complex Organization Macromolecule Biosynthetic Process Allantois Development TFIIB-class Transcription Factor Binding Spermatogonial Cell Division RNA Polymerase Transcription Factor SL1 Complex Transcription Factor TFIIA Complex Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription RNA Polymerase II General Transcription Initiation Factor Binding Pronucleus DNA Replication-dependent Chromatin Assembly Positive Regulation Of RNA Metabolic Process Male Pronucleus Aryl Hydrocarbon Receptor Binding RNA Polymerase I Core Promoter Sequence-specific DNA Binding Nucleobase-containing Compound Biosynthetic Process RNA Polymerase I Preinitiation Complex Assembly Female Pronucleus Co-transcriptional RNA 3'-end Processing, Cleavage And Polyadenylation Pathway Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nucleic Acid Metabolic Process RNA Polymerase III General Transcription Initiation Factor Activity Transcription Preinitiation Complex Female Germ Cell Nucleus Gene Expression
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