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TNIP2 and MKNK1
Number of citations of the paper that reports this interaction (PMID
21988832
)
14
Data Source:
BioGRID
(two hybrid)
TNIP2
MKNK1
Gene Name
TNFAIP3 interacting protein 2
MAP kinase interacting serine/threonine kinase 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Nucleus
Cytosol
Molecular Function
Protein Binding
Protein Kinase Binding
Polyubiquitin Binding
Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Biological Process
Transcription, DNA-templated
Apoptotic Process
Inflammatory Response
I-kappaB Kinase/NF-kappaB Signaling
CD40 Signaling Pathway
Toll-like Receptor 2 Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Toll-like Receptor 9 Signaling Pathway
Positive Regulation Of Macrophage Activation
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Protein Stabilization
Positive Regulation Of B Cell Activation
Interleukin-1-mediated Signaling Pathway
Cellular Response To Lipopolysaccharide
Negative Regulation Of Endothelial Cell Apoptotic Process
Regulation Of Translational Initiation
Protein Phosphorylation
Fibroblast Growth Factor Receptor Signaling Pathway
Response To Salt Stress
Peptidyl-serine Phosphorylation
Intracellular Signal Transduction
Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways
Signaling by Interleukins
Cytokine Signaling in Immune system
Interleukin-1 signaling
Signaling by FGFR in disease
Spry regulation of FGF signaling
Signaling by FGFR
Negative regulation of FGFR signaling
Drugs
Diseases
GWAS
Protein-Protein Interactions
23 interactors:
APP
CDKN1A
CHUK
EP300
FBXO25
FLNA
IKBKG
MAP3K8
MAPK1
MKNK1
NCOR2
NFKB1
NFKB2
PDCD6IP
PSMD9
REL
RELA
SMARCD1
SRPK2
STK11
TEK
TNFAIP3
UBC
25 interactors:
APP
ATXN3
CREBBP
DDAH2
DNAJC7
EIF4E
EIF4G1
EIF4G2
EIF4G3
FANCA
HGS
HIPK2
HSP90AB1
MAPK1
MAPK14
MAPK3
MBP
PAK2
PHAX
PLA2G4A
PRKDC
RCN3
SPRY2
TNIP2
UBE2D1
Entrez ID
79155
8569
HPRD ID
18207
09468
Ensembl ID
ENSG00000168884
ENSG00000079277
Uniprot IDs
D6RGJ2
Q8NFZ5
A8K341
Q9BUB5
PDB IDs
2HW6
2Y9Q
Enriched GO Terms of Interacting Partners
?
Intracellular Signal Transduction
Toll-like Receptor 5 Signaling Pathway
Toll-like Receptor 10 Signaling Pathway
Innate Immune Response
Regulation Of Type I Interferon Production
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Toll-like Receptor 2 Signaling Pathway
Immune System Process
Toll-like Receptor 9 Signaling Pathway
TRIF-dependent Toll-like Receptor Signaling Pathway
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
MyD88-dependent Toll-like Receptor Signaling Pathway
Apoptotic Process
Activation Of Innate Immune Response
Positive Regulation Of Type I Interferon Production
Toll-like Receptor 4 Signaling Pathway
Programmed Cell Death
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Cell Death
Death
Positive Regulation Of Cellular Metabolic Process
Regulation Of Protein Metabolic Process
Positive Regulation Of Innate Immune Response
Immune Response-regulating Signaling Pathway
Positive Regulation Of Immune System Process
Toll-like Receptor Signaling Pathway
T Cell Receptor Signaling Pathway
Positive Regulation Of Metabolic Process
Response To Stress
I-kappaB Kinase/NF-kappaB Signaling
Immune Response
Positive Regulation Of Cytokine Production
Regulation Of Cytokine Production
Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Defense Response
Antigen Receptor-mediated Signaling Pathway
Regulation Of Innate Immune Response
Signal Transduction
Regulation Of Immune Response
Positive Regulation Of Immune Response
Positive Regulation Of Gene Expression
NIK/NF-kappaB Signaling
Positive Regulation Of Protein Metabolic Process
Signaling
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Protein Metabolic Process
Cellular Response To Organic Substance
Posttranscriptional Regulation Of Gene Expression
Regulation Of Cellular Protein Metabolic Process
Response To Organic Substance
Signaling
Cellular Response To Stimulus
Cell Communication
Cell Surface Receptor Signaling Pathway
Cellular Response To Heat
Enzyme Linked Receptor Protein Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Response To Stimulus
Response To Cytokine
Defense Response
Regulation Of Cellular Response To Heat
Viral Process
Response To Abiotic Stimulus
Innate Immune Response
Signal Transduction
Cellular Response To Cytokine Stimulus
Toll-like Receptor Signaling Pathway
Response To Stress
Response To Heat
Peptidyl-serine Phosphorylation
Regulation Of Innate Immune Response
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Pattern Recognition Receptor Signaling Pathway
Immune Response
Positive Regulation Of Cellular Metabolic Process
Innate Immune Response-activating Signal Transduction
Cellular Protein Metabolic Process
Regulation Of Translation
Immune Response-regulating Signaling Pathway
Immune System Process
Activation Of Innate Immune Response
Cell Cycle
Toll-like Receptor 2 Signaling Pathway
Toll-like Receptor 9 Signaling Pathway
Cell Death
Death
TRIF-dependent Toll-like Receptor Signaling Pathway
Regulation Of Protein Phosphorylation
MyD88-independent Toll-like Receptor Signaling Pathway
Positive Regulation Of Metabolic Process
Positive Regulation Of Cellular Protein Metabolic Process
Gene Expression
Cellular Response To Stress
Positive Regulation Of Transferase Activity
Positive Regulation Of Gene Expression
Tagcloud
?
4ebp1
90kda
alphas1
alphas2
casein
caseins
cows
dairy
eif4e
eif4g
export
igfbp3
igfbp5
lactating
mtorc1
nonpregnant
nucleocytoplasmic
p70
p85
parenchymal
patsearch
rps6ka1
s6k
ser209
ser2448
ser65
thr197202
thre389
thre412
Tagcloud (Difference)
?
4ebp1
90kda
alphas1
alphas2
casein
caseins
cows
dairy
eif4e
eif4g
export
igfbp3
igfbp5
lactating
mtorc1
nonpregnant
nucleocytoplasmic
p70
p85
parenchymal
patsearch
rps6ka1
s6k
ser209
ser2448
ser65
thr197202
thre389
thre412
Tagcloud (Intersection)
?